glial derived neurotrophic factor 中文意思是什麼
glial derived neurotrophic factor
解釋
膠質細胞衍生的神經營養因子- glial : 神經膠質的
- derived : 導生的
- neurotrophic : 神經營養的
- factor : n 1 〈英國〉經銷人；（代客買賣收取傭金的）經紀人；代理商；代辦人；〈蘇格蘭語〉 土地經管人。2 要素...
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Glial cell line - derived neurotrophic factor ( gdnf ) was originally isolated based on its potent and specific ability to promote the survival and morphological differentiation of dopaminergic neurons and motoneurons in embryonic midbrain cultures. in addition, gdnf also support the survival and regulate the differentiation of many peripheral neurons, including sympathetic, parasympathetic, sensory and enteric neurons. gdnf also plays a crucial role outside the nervous system, as a morphogenetic factor in kidney development and as a regulator of spermatogonia differentiation
Gfr 1與gdnf結合位點的研究膠質細胞源性神經營養因子（ gdnf ）對多巴胺能神經元、運動神經元、感覺神經元、腸道神經元等多種神經元具有促進存活及保護作用，它還能促進腎臟的發育和精原細胞的成熟，因此，極有希望用於治療神經損傷和神經系統退行性病變。 -
Effects of glial derived neurotrophic factor on focal cerebral ischmia in rats
膠質細胞源性神經營養因子對大鼠局灶腦缺血損傷的作用 -
A pilot study of the role of glial cell line derived neurotrophic factor in the pain regulation
膠質細胞源性神經營養因子對中小型神經元痛溫覺調控研究 -
Protective effects of exogenous glial cell line - derived neurotrophic factor on spinal motor neurons in rats with peripheral nerve injury
外源性膠質細胞源性神經營養因子對周圍神經損傷大鼠脊髓運動神經元的保護作用 -
Construction of recombinant adeno - associated virus vector expressing glial cell line - derived neurotrophic factor labeled by green fluorescent protein
綠色熒光蛋白標記的大鼠膠質細胞源性神經營養因子重組腺病毒載體的構建及其表達 -
In the present experiment studies, an acute traumatic model of lateral cortical impact was employed to study expressive changes of microtubule associated protein - 2 ( map - 2 ), cyclooxygenase - 2 ( cox - 2 ), glial cell line - derived neurotrophic factor ( gdnf ), caspase - 3 mrna and protein after brain injury in rats. immunocytochemical staining, western blotting, nucleic acid in situ hybridization with an oligonucleotide probe and computer image analysis were used to detect the dynamic changes of map - 2 mrna, cox - 2 mrna, gdnf mrna, and caspase - 3 mrna in the cortex after moderate traumatic brain injury ( tbi )
本實驗從自行設計大鼠腦損傷落體打擊器開始，先行建立了一個便於觀察和施加處理因素、控制性好、重復性好的動物模型，選用30g擊錘從25cm高處下落，沖擊應力d為355 . 09kpa ，打擊大鼠右頂部，造成中等程度的閉合性腦損傷，從病理形態學、組織超微結構觀察及微管相關蛋白- 2 （ microtubuleassociatedprotein2 ， map - 2 ） 、環氧合酶- 2 （ cyclooxygenase2 ， cox - 2 ） 、膠質源性神經營養因子（ glialcellline - derivedneutrophicfactor ， gdnf ） 、 caspase - 3基因及蛋白表達的時間性變化，詳盡系統地闡述腦損傷后各指標變化的時間規律性及表達差異可能的形成機制。
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