hydrophobic region 中文意思是什麼

hydrophobic region 解釋
疏水區
  • hydrophobic : 不吸水的
  • region : n. 1. 地方，地域，地帶；地區；行政區，管轄區，區；左近，鄰近；（大氣、海水等的）層，界，境。2. 【解剖學；動物學】（身體的）局部，部位。3. （學問等的）范圍，領域。4. 〈罕用語〉天空。
  1. The pocket accommodating the aromatic ring of phenylalanine is formed predominantly by hydrophobic side - chains, including those of ile10, ile13, prol50, leul75, leul79, phe209, ser211 and val221 ; whilst the amino group and carboxylate group of phenylalanine is coordinated by asp6, asp7, gln151 and ser180. the n - terminal region is found to be important to the function of arog. point mutation reveals that residue substitution of ilelo to ala10 leads to desensitization in the presence of 1 mm phenylalanine, simultaneously, exhibits a dramatic decrease in enzymatic activity

    綜合前人的研究和本研究工作的實驗數據，得出以下結論： 1 ）在arog的反饋抑制位點供苯丙氨酸結合的疏水口袋由asp6 、 asp7 、 ile10 、 ile13 、 pro150 、 gln151 、 leu175 、 leu179 、 ser180 、 phe209 、 ser211和val221等12個氨基酸殘基構成； 2 ）苯丙氨酸結合的疏水口袋分為兩個區域，與苯丙氨酸的苯環發生疏水作用的區域由ile10 、 ile13 、 pro150 、 leu175 、 leu179 、 phe209和val221的側鏈構成，而asp6 、 asp7 、 gln151和ser180的側鏈構成了與苯丙氨酸的氨基和羧基相互作用的區域。
  2. Initially, a polyclonal antibodies was used to screen the cdna expression library to isolate pf40 gene from millet. sequence analysis revealed that the pf40 gene contained an open reading frame ( orf ) encoding a protein with 75 % - 35 % sequence identity to the zips ( zinc or iron transporter proteins ) gene family. software analysis of the pf40 gene character showed that pf40 protein had a eight trans - membrane region structure, pf40 protein was also rich in leucine ( 18. 4 % ) and the protein was a hydrophobic protein

    序列分析表明該基因具有一個開放閱讀框（ openreadingframe ， orf ） : genbank中查詢該基因編碼的蛋白與zips （ zincorirontransporterproteins ，離子通道蛋白）基因家族的蛋白有75 - 35的相似性；軟體的分析結果顯示該基因編碼的蛋白為一個有8個跨膜區的跨膜蛋白； pf40蛋白為疏水蛋白，以上的特徵也許是pf40基因發揮作用的基礎。
  3. Ag + and fe2 + caused the fluorescence of trp residues in g6pd quenched ; mg2 + and edta made fluorescence intensity of g6pd increased, this indicates that they caused trp residues wrapped and came to the inner core and located in the hydrophobic area ; while zn2 + or mn2 + made fluorescence intensity of g6pd decreased, this indicates that they made the conformation of g6pd relaxed and chromophores exposed to polarity environments. in native condition and in the far circular dichroic ( cd ) region, g6pd exhibited two characteristic negative band centered at 208nm and 222nm respectively, thus it is estimated to contain about 41. 2 % a - helix, 20. 6 % - pleated sheet and 38. 2 % random coil and turn

    Ag ~ +和fe ~ （ 2 + ）引起色氨酸（ trp ）殘基的熒光淬滅； mg ~ （ 2 + ）和edta均使g6pd的熒光強度增強，說明它們使trp殘基重新包裹在分子內部而處于疏水的微環境中； zn ~ （ 2 + ）和mn ~ （ 2 + ）均使g6pd的熒光強度變小，說明它們使酶分子構象變得疏鬆，原來處在分子內部的發色團暴露在極性環境中。
  4. Hydrophobicity analysis predicted a 36 - residue hydrophobic signal peptide for secretion in the n - terminus, and no transmembrane region was present, suggesting it might be a type of secretory protein. some generic and atipical n - glycosylation sites were present in clsp, suggesting that the protein might represent a glycoprotein. the clsp protein contained one cub ( clr / cls, an embryonic sea urchin protein uegf, and bone morphogenetic protein i ) domain from 39th to 164th ammo acids, which is known to be involved in protein - protein or protein - substrate interaction, and a trypsin - like serine protease domain positioned from 244th to 483rd amino acids

    Clsp分子具有補體樣絲氨酸蛋白酶的多種結構特徵，包括36個氨基酸組成的疏水信號膚，一個cub （ clr / cls ， anembryonicseaurehinproteinuegf ， andbonemorphogeneticproteinl ）結構域和一個胰酶樣絲氨酸蛋白酶結構域（ t汀psin一likeserineproteasedomain ）和幾個保守的糖基化位點等，沒有發現有跨膜區的存在。
  5. The gene was 1668bp in length, encoding the f protein composed of 553 amino acids. sequence analysis and its secondary structure prediction showed that the f protein had three major hydrophobic regions consisting of about 25 amino acids, six potential glycosylation sites and thirteen cysteines. a sequence region of basic amino acids, rrqrrf, was found at the f, - f2 cleavage site, indicating that f4ge9 was a typical virulent strain

    序列分析和二級結構預測表明， f _ （ 48 ） e _ （ 9 ）株f蛋白含有3個分別由25個氨基酸組成的疏水區，存在6個潛在的糖基化位點， 13個半胱氨酸殘基，裂解位點區域的氨基酸序列為rrqrrf ，說明f _ （ 48 ） e _ 9株是一株典型的強毒株。
分享友人
分享到 Line

分享到臉書