intracellular binding 中文意思是什麼

intracellular binding 解釋
細胞內接合
  • intracellular : adj. 細胞內的；發生於個體細胞內的。
  • binding : adj 1 縛[捆、綁]…的；黏合的；系連的，連結的。2 有束縛力的，有拘束力的，附有義務的。3 〈口語〉引起...
  1. Subsequently. it has been found in all normal cells examined so far except the kidney cells. tctp homologues among the species are highly conserved, which suggest that the protein might have an essential function in cell. lt was reported that tctp caused the release of histamine from ige + basophils and was capable of various functions including calcium binding. metal homeostasis, intracellular signaling and reacting with antimalarial drugs

    從植物到動物的各類細胞中， tctp都有廣泛的高度同源性和高度保守性，提示tctp在細胞中有重要的生物學功能。雖然報道認為tctp具有鈣結合、金屬內環境穩定、細胞內信號傳導、作為ige依賴性組胺釋放因子等功能，但其具體生物學功能尚待進一步研究闡明。
  2. Our previous studies showed existence of apoplast cam in the plant cell and cam had many extracellular functions. so it supposed cam may be one of important extracellular polypeptides and trigger the intracellular signal transduction by binding the receptor. in this study, radiolabelled ligand is used to investigate the binding characteristic of cam and a. thaliana protoplasts. and chemical crosslinking is employed to explore binding proteins in the membrane. at first, ( 35 ) ~ s - cam was produced using ( 35 ) ~ s - labeled amino acid mixture in e. coli. sds - page and autoradiograph indicated high - purified, high - specific radioactivity ( 35 ) ~ s - cam was obtained. electrophoresis of ( 35 ) ~ s - cam is the same as that of unlabeled cam with ca ~ ( 2 + ) or egta ; a quatitive of protoplasts was prepared by enzymolysis

    首先，用~ （ 35 ） s標記的氨基酸混合物喂養工程菌成功地制備了~ （ 35 ） s標記的擬南芥鈣調素（ ~ （ 35 ） s - cam ） ， ~ （ 35 ） s - cam純度高、放射活度高、 ca ~ （ 2 + ）與egta存在時的電泳行為與未標記cam相同，可作為一種高靈敏性的探針用於進行受體學分析實驗；用擬南芥種子誘導愈傷，通過酶解制備了大量原生質體。
  3. For example, the signal transduction of g protein - coupled receptor is mediated by g protein and can generate intracellular messages ; there exist some transmembrane proteins in the membrane of endoplasmic reticulum, and some of them are related with the synthesis and transportation of some proteins, while others are related with substance metablism, such as glucose - 6 - phosphatase ( g6pase ). in addition, after binding with the 7 - tm receptors affiliated to frizzled protein family, wnt can activated disheveled protein in cytoplasm which is essential to embryonic development

    如g蛋白偶聯受體通過g蛋白介導產生胞內信使（ camp ， cgmp ， dg ， ip _ 3 ）將胞外信號傳遞到胞內，從而引起生物學效應；內質網上也存在著一些跨膜蛋白，其中一些與蛋白質的合成及運輸有關，一些與物質代謝有關，如葡萄糖- 6 -磷酸酶。
  4. Calbindin d - 28k ( cb ) is an important member of calcium - binding protein family and has a high affinity for binding ca - ", one of the important intracellular messengers. the cb has been regarded as a selective mark er of some neuronal populations especially of projection neurons in various regions of the central nervous system

    Calbindind - 28k （ cb ）是生物體內一種與鈣離子具有較高親合力的蛋白質，作為中樞神經系統一些部位內神經元特別是投射神經元的特異性標識物被廣泛應用。
  5. The npr - c is a membrane - bound receptor that lacks the intracellular guanylate cyclase domains of the biologically active receptors and is therefore uncoupled with cgmp. npr - c functions as a clearance receptor by binding with and internalizing natriuretic peptides. nprs are widely and differently distributed in most tissues and can be up - or down - regulated in many pathological processes, which indicates that they have different effects on different tissue and participate in the regulation of their physiological and pathological process

    正常情況下，三種受體在體內均廣泛分佈，但在不同組織中的分佈有很大差異，而且在不同病理條件下鈉尿肽受體數目還可發生上調和下調，提示鈉尿肽家族及其受體對不同組織器官的作用不同，並參與它們的生理和病理過程的調節。
  6. In order to get some functional clues from their structures, the upstream regulation region of ndrgl gene and second structure of ndrg2 protein are performed bioinformatics analysis ; we found that there are several binding sequences of some diffirent transcription factors, their functions include regulating tissue - specific gene expression, regulating expression of genes related to growth and early development of cells, besides this, regulating expression of genes under some stimulated conditions, and so on. predict in protein fold classification shows that ndrg2 belongs to alpha / beta hydrolase fold family, and there are high similarity between ndrg2 and epoxide hydrolase from bacteria, this suggests that ndrg2 protein may has enzymatic functions associated with resisting the oxidative stress, maintaining the balance of cell redox potential, involving in the metabolism process of xenobiotics or intracellular toxic molecules

    研究發現呷基因的調控區存在多種轉錄因子結合位點，功能主要涉及組織特異性表達調控，細胞生長發育相關基因的表達調控，刺激反應基因的表達調控等； ndrgz蛋白在結構上屬于a小水解酶類折疊，折疊分類預測表明ndrg2與其中的的細菌環氧化物水解酶的二級結構極為相似，提示ndrgz蛋白具有一定酶活性，可能參與細胞抗氧化應激反應，維持細， an ） armtbffiofbfochmilsyn ） mdafblechmrbfobo4第四軍醫大學碩士學位論文胞內氧還電勢平衡，參與內外源有毒物質的代謝等。
  7. By yeast two - hybrid assay, aes was found to interact with gp130 intracellular region through its conserved q domain. results from the yeast two - hybrid assay, gluthione s - transferase fusion protein pull - down assay and immuno - co - precipitation assay indicated that the q domain of tle1 is capable of binding gp130 intracellular domain, and the intracellular membrane proximal region of gp130 containing conserved boxl and box2 motifs seemed essential for this interaction. to investigate the consequence of this interaction, tle1 - gfp fusion protein expression vector was constructed and co - transfected into nih 3t3 cells with gp130 expression vector

    在通過酵母雙雜交分析確定aes通過q結構域與sp130分子胞漿區結合的基礎上，為確定tle1分子是否也能通過保守的q結構域與gp130分子胞漿區結合，我們通過pcr擴增編碼gp130胞漿區與tleq分子不同結構域的cdna ，構建了含有這些不同結構域的酵母雙雜交載體，通過酵母雙雜交分析證實： tle1分子通過其氨基端的q結構域與gp130分子胞漿區近膜段結合。
  8. 2. we use the novel copper binding protein as antigen, prepared rabbit anti rat copper binding protein polyclonal antibody. discussion recently, a number of proteins, that play significant roles in intracellular copper homeostasis, were identified in various species, ranging from bacteria to humans

    討論近年來的研究發現了多種在不同生物種系維持細胞內鋼平衡的蛋白，這些蛋白分佈較廣，從噬菌體到人類都存在具有這種功能的蛋白質，分為銅伴侶和銅轉運體兩種。
  9. The intracellular region of notchl transactivates genes by interacting with a dna binding protein rbp - j, which plays an important role in notch signaling

    人們將該途徑稱為notch途徑， notch途徑中最核心的信號分子之一為rbp - j 。
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