jak-stat 中文意思是什麼
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Jak2 is one of the janus kinase family. it participates in the jak - stat signal transduction and plays roles in signal transduction of many cytokins and growth factors such as growth hormone, il and gm - csf. it plays essential roles in cellular functions, i. e. cell proliferation and differentiation
Jak2是janus激酶家族中的一員,參與jak - stat信號通路,介導諸如生長激素、白細胞介素、 gm - csf等細胞因子和生長因子的信號傳導,在細胞的增殖、分化等活動中起重要作用。 -
12 yamada s, shiono s, joo a, yoshimura a. control mechanism of jak stat signal transduction pathway. febs lett., 2003, 534 : 190 - 196
另外我們還模擬了單個信號蛋白的初始濃度的變化對系統輸出的影響,從而可以看出一些關鍵蛋白組分對系統變化的貢獻。 -
Stat proteins are activated by g - protein coupled receptors, while it has not been reported whether cck receptors, a kind of g - protein coupled receptors, can activate jak / stat pathway
Stat蛋白可被g蛋白偶聯受體激活,而cck受體作為一種g蛋白偶聯受體,是否對jak stat通路具有直接激活作用,尚未見報道。 -
10 o shea j j, gadina m, schreiber r d. cytokine signaling in 2002 : new surprises in the jak stat pathway. cell, 2002, 109 suppl : s121 - s131. 11 boehm u, klamp t, groot m, howard j c. cellular responses to interferon - gamma
魯棒性的結論表明jak - stat信號通路的「信號時間」 signal time和「信號持續時間」 signal duration對外界擾動比較魯棒,而「信號幅度」 signal amplitude則對外界擾動比較敏感。 -
Robustness analysis of the ifn - induced jak - stat signaling pathway
干擾素誘導的jak - stat信號通路的魯棒性分析 -
Here, the issue of robustness analysis of cell jak - stat signal transduction networks is addressed
因此我們有必要研究細胞在不同生理狀況下的變化情況。 -
This is investigated upon a mathematical model of ifn - induced jak - stat signaling pathway by applying robustness analysis which is based on a broad range of simultaneous and systematical parameters variation
我們對細胞的jak - stat信號建立了數學模型,同時系統地改變模型中的動力學參數反應速率參數,然後進行大量的數值模擬實驗。 -
The effects of the variations of the initial signal proteins concentrations on the output of this system are also studied. the study demonstrates that the jak - stat signaling pathway is robust with respect to its signal time and signal duration, but sensitive with respect to its signal amplitude
我們主要考察了細胞信號轉導過程中三個重要的特徵量的變化,即「信號時間」 signal time 「信號持續時間」 signal duration以及信號幅度signal amplitude 。 -
Jak stat signaling paradigmjak stat
信號發送典範
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