ligand binding 中文意思是什麼
ligand binding
解釋
配體結合-
Recently, ldl apheresis has been applied in clinic and achieves a satisactory effect. in this dissertation, the tripeptide, serine - aspartic - glutamic acid ( sde ), which existes in the cooh - terminal end of the seven repeats in the ligand binding domain of the ldl receptor and plays an important role in identifying ldl, was synthetized and immobilized onto the polyacrylamide ( paam ) beads as a bionic adsorbent for selective removal of ldl from plasma
本論文以絲氨酰-天冬氨酰-谷氨酸（ sde ）負電性三肽（此三肽廣泛存在於ldl受體配體結合域7個重復序列的羧基末端，對ldl受體特異性識別ldl起著重要作用）作為配體固定到聚丙烯酰胺微球載體上製成仿生性ldl親和吸附劑，考察其對人血漿中ldl及hdl的吸附功效。 -
Our previous studies showed existence of apoplast cam in the plant cell and cam had many extracellular functions. so it supposed cam may be one of important extracellular polypeptides and trigger the intracellular signal transduction by binding the receptor. in this study, radiolabelled ligand is used to investigate the binding characteristic of cam and a. thaliana protoplasts. and chemical crosslinking is employed to explore binding proteins in the membrane. at first, ( 35 ) ~ s - cam was produced using ( 35 ) ~ s - labeled amino acid mixture in e. coli. sds - page and autoradiograph indicated high - purified, high - specific radioactivity ( 35 ) ~ s - cam was obtained. electrophoresis of ( 35 ) ~ s - cam is the same as that of unlabeled cam with ca ~ ( 2 + ) or egta ; a quatitive of protoplasts was prepared by enzymolysis
首先，用~ （ 35 ） s標記的氨基酸混合物喂養工程菌成功地制備了~ （ 35 ） s標記的擬南芥鈣調素（ ~ （ 35 ） s - cam ） ， ~ （ 35 ） s - cam純度高、放射活度高、 ca ~ （ 2 + ）與egta存在時的電泳行為與未標記cam相同，可作為一種高靈敏性的探針用於進行受體學分析實驗；用擬南芥種子誘導愈傷，通過酶解制備了大量原生質體。 -
Development and applications of the theory and method for polarization energy decomposition to study intermolecular interactions in condensed phases and protein - ligand binding
在研究凝聚態和蛋白質-配體連接中的分子內相互作用時，發展了極化能分解理論和方法。 -
The binding characteristics of the opioid ligand
受體激動劑對穩定轉染 -
Determination of a fine binding site of ligand to fibroblast growth factor receptor
成纖維細胞生長因子受體1配體精細結合位點的確定 -
Screening and constructional analysis of extracellular at the ligand binding domain of the vascular endothelial growth factor receptor flt
胞外配體結合域的篩選及其結構分析 -
Some albumin molecules may hae undergone steric modification or ligand binding such that the immunoreactie sites hae become obscured
某些白蛋白分子也許經歷了空間修飾或配體結合上的改變以至於其免疫反應位點被湮沒。 -
Consequent upon the structural flexibility and the ligand binding, circulating albumin exhibits chemical and physical microheterogeneity
由於其結構上的易變性和配體結合的不同，循環中的白蛋白表現出化學和物理上的微觀不均一性。 -
These can include animal - based, cell culture - based, biochemical, or ligand / receptor - binding assays
這些分析方法可以包括基於動物的，細胞培養的，生物化學的或配位體/接受體螯合的分析方法。 -
Using a computer program, a peptide was deduced from residues 256 - 265 of human fas ligand, based on the hypothesis that it should contain a specific binding site to the corresponding fas. this short peptide and fas contain 70 % of sense - antisense pairs
本研究依據ahbs理論，應用自行編寫的軟體，在fasl分子中尋找到與fas相應的反義多肽最為接近的十肽結構即fasl _ （ 256 - 265 ） （匹配度為70 ） 。 -
Prolonged uremia significantly alters the ligand - binding properties of albumin, and albumin contributes to whole blood acid - base buffering capacity
持續的尿毒癥明顯改變了白蛋白的配體結合特性，而白蛋白也與血液酸堿緩沖能力有關。 -
Notch proteins are a family of evolutionarily conserved transmembrane receptors which are involved in cell fate determination of many cell lineages. notch ligand delta is also transmembrane protein with characteristic cysteine - rich n - terminal domain responsible for notch binding
Notch基因廣泛表達于胚胎發育過程中的各種組織和各種成熟組織中具有增殖能力的細胞層，該基因編碼一個由2753個氨基酸殘基的型跨膜蛋白分子受體，其配體也是細胞膜蛋白，稱為delta 。 -
The screening on affinity ligand of heart - type fatty acid - binding protein
心肌型脂肪酸結合蛋白特異性親和配體的篩選 -
The result indicates that the mg2 + ion around the binding site is very important to stabilize the binding of the ligand to the receptor. the binding free energy estimated by the empirical function favors the system with one mg2 + ion, in which the free energy is about 5 kcal / mol less than the system with mg2 + ion
含有mg2 +離子的情況下比不含mg2 +離子的體系之間的自北京工業大學工學碩士論文一由能之差為一5kcal m ，結果說明結合位點處的mg 『 」離子對穩定配體與受體的結合起了重要作用。 -
Generally, the protein - protein docking procedure is composed of four stages : searching of the binding modes of the receptor and the ligand, filtering of docked modes to eliminate the irrational docked structures, optimizing the structures, evaluating the docked modes with the refined scoring function and ranking them to obtain the near - native structures
通常，蛋白質蛋白質分子對接包括四個階段：搜索受體與配體分子間的結合模式，過濾對接結構以排除不合理的結合模式，優化結構，用精細的打分函數評價、排序對接模式並挑選近天然構象。 -
Proteinmicroarrays can be based on any ligand - binding assay that relies on theformation of product with an immobilized capture molecule and a targetmolecule present in the solution
蛋白質晶元可以基於任何配體結合實驗，靠產品形成一個固定捕捉目前在分子和分子靶解 -
The latter plays a very important role in the study of the mechanism and dynamics of the recognition. it includes the molecular modeling, confirming the binding sites, the calculation of interactions between receptor and ligand, the docking research of the complex, the calculation of dynamic and thermodynamic properties etc. many theoretical calculation methods are involved, such as quantum chemistry, molecular mechanisms, molecular dynamics, monte carlo method and free energy calculation and so on
其中計算機模擬方法是研究分子識別機制及其動態過程的重要途徑，包括底物及受體分子模型的構建、底物及受體相互作用位點的確定、相互作用力的計算、底物及受體分子的對接及其動態過程的研究、體系熱力學及動力學性質的計算等方面內容。 -
The activation of notch by binding with notch ligand can lead to inhibition of cell differentiation
當notch受體受到配體的刺激而激活時，可以傳導分化抑制信號。
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