mammalian toxicity 中文意思是什麼
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So the results indicate that the two mutants have no significant difference in the toxicity of inhibiting mammal neuron sodium channels, and ala20 or ser20 was not the key residue. the two peptide neurontoxins inhibite mammalian voltage - gated sodium channels through a novel mechanism distinct from other known spider toxins such as 5 - actxs, - agatoxins i - vi which banded receptor site 3 to slow the inactive time course of sodium channels. we suggest that hntx - v maybe target the site 1 of sodium channels in a similar manner to - conotoxins and ttx
同時兩種海南捕鳥蛛毒素從影響ttx一s鈉通道的方式上來看，與其它已知膚類蜘蛛毒素如6一actxs等通過作用於位點3引起延緩鈉通道的失活時間存在明顯不同，我們推測hntx一iv和iintx一v可能是以一種新的不同於其它蜘蛛毒素的方式來影響鈉通道的，而ttx一s鈉通道位點1則很有可能便是它們的作用位點，與ttx和林一eonotoxins相似。 -
Mutated plasmid was transformed into e. coli tg1 cells to produce engineered peptide, then the peptide was purified by cm sepharose ion - exchange column. in vitro bactericidal assay and drug withdrawal were used to identify the bioactivity of the engineered peptide. the planar lipid bilayer membrane was used to assay the electrophysiology of the engineered peptide. toxicity studies on mammalian cells were used to assay the toxicity of the engineered peptide
將重組質粒轉化入大腸桿菌tgi工程菌中，生產構建的工程多膚，離子交換純化后獲得工程多膚初步純化產物，體外抗菌試驗、藥物撤離試驗檢測工程多膚的抗菌活性，在人工脂質膜上測定其形成離子通道的特性以初步研究抗菌機理， ?並觀察其對真核細胞的毒性作用。 -
Standard test method for mammalian acute percutaneous toxicity
哺乳動物急性經皮毒性的試驗方法
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