mapk 中文意思是什麼

mapk 解釋
促分裂原活化蛋白激酶
  1. Especially, at the site of implantation of day 5, 6, uterine stroma cell apposing the preimplantation blastocyst changed into the decidual cells and displayed a distinct immunostaining of phospho mapk. western - blot results showed p44 express stronger than p42 did, with both their peak expression were observed on day 5, during the period of uterine decidualization

    上述結果表明， ma衛k的激活與子宮內膜的接受性及蛻膜的形成有密切關系，推測mapk級聯通路激活對蛻膜化十分重要，蛻膜化可能與egf尼gfr直接或間接激活erk有關。
  2. The degradation of i k b and dissociation from nf - k b complex are essential process for activation of nf - k b. there is no report about whether cck - 8 inhibits nf - k b activity through inhibiting lps - induced degradation of i k b. the present study was designed to observe the regulatory effect of cck - 8 on changes of immune functions induced by lps, the receptor mechanism and signal transduction mechanism involving mapk, stat3 and i k b at different levels including in vivo and in vitro, in order to study its immunomodulatory effect on reversing es and its molecular mechanisms

    Ikb的降解、並從w兒b復合物上解離是w4b激活的必需過程。 ccks是否通過抑制lps誘導的ikb降解，從而抑制nf幾b激活尚未見報道。本研究在整體、細胞及分子水平，觀察了ccke對lps引起的免疫功能改變的調節作用，研究了其受體機制及mapk 、 stat3和ikb的信號轉導機制，以探討cck七抗es時的免疫調節作用及其分子機制。
  3. Interestingly, inhibition of p38 mapk activation ( but not erk activation ) by its inhibitors or by expression of a dominant negative mutant of p38 mapk could effectively block the chemotactic effect of ( - arrestin2

    P38mapk上游激酶ask1的顯性失活突變體也可以阻斷- arrestin2對趨化的增強作用。這說明是p38mapk而不是erk信號通路與- arrestin2對趨化的增強作用相關。
  4. Taken together, our study suggests that ( - arrestin2 can function not only as a regulator of cxcr4 signaling but also as a mediator of sdf - 1 ( - induced chemotaxis and this is probably via the ask1 / p38 mapk pathway

    綜上所述， - arrestin2參與介導了cxcr4引起的趨化作用，這種作用可能是通過調節p38mapk / ask1信號通路來實現的。
  5. Further analysis reveals that expression of ( - arrestin2 strengthened cxcr4 - mediated activation of both p38 mapk and erk and the suppression of ( - arrestin2 expression blocked the activation of two kinases

    進一步的研究發現， - arrestin2可以增強cxcr4介導的erk及p38mapk的激活，但只有p38mapk的特異性抑制劑及顯性失活突變體才可以阻斷- arrestin2對趨化的增強作用。
  6. Study on function of mapk and mpf in mitosis of mouse fertilized eggs

    對小鼠受精卵有絲分裂期作用
  7. Cck activates mapk in pancreatic acinar cells

    在胰腺腺泡細胞cck可激活mapk 。
  8. Mapk signal transduction path and psoriasis

    信號轉導通路與銀屑病
  9. There are still many questions remain unanswered, including the mechanisms that specify oligochitosan recognition, the participation of additional molecules in transmembrane signaling, and the repertoire of downstream pathways activated by oligochitosan. it was also observed that pdtc did not totally block no production, which gave us another evidence that there must be some other signal transduction pathways ( perhaps mapk, pkc, ca2 + dependent signaling ) involved in the activation, so further investigation is necessary to clarify molecular mechanism of oligochitosan inducing immunological en

    Westemblot結果顯示100林歲ml劑量的殼寡糖作用於raw264 . 7細胞（ 4x105個細胞/ ml ） 4h ，胞核內p65的含量明顯增加， 6h時達到高峰， 10h時恢復到基礎表達量，這就提示在殼寡糖對巨噬細胞的激活過程中nf一kb活化狀態可以持續6個小時。
  10. In plants, mapk module can be used for the transmission of multiple signals, including osmotic and oxidative stress

    植物中map激酶信號轉導途徑參與多種脅迫信號的傳遞，包括滲透脅迫和氧化脅迫等。
  11. Cck may play immunomodulatory role in es by activating stat through p38 mapk and regulating gene transcription

    Cck也可能通過激活p38mapk進而激活stat ，調控基因轉錄，發揮對es的免疫調節作用。
  12. Inhibitory effects of antisense oligonucleotides targeting mitogen - activated protein kinase mapk mrna on neonatal rat cardiac fibroblast proliferation induced by ang and egf

    反義mapk寡核苷酸對ang及egf誘導的心肌成纖維細胞增殖的抑制效應
  13. There are two egfr signaling pathways, one is the classical ras / raf / mek / mapk pathway and the other is pi - 3 - k / pkb pathway. in this part, the phosphorylation and / or activity of some key molecules in these two signaling pathways in differently transfected h7721 cells were investigated. by means of specific antibodies combined with weste

    Egf刺激后不同轉染細胞中的pkb活性、 p42 / 44mapk和mek磷酸化都明顯增加，其中gntv一s / h7721細胞pkb比活性、 p42 / 44mapk和mek磷酸化程度較mock細胞增加明顯，而gntv一as / h7721細胞中上述指標的增加程度則不及mock細胞。
  14. Mitogen activated protein kinase, mapk

    及絲裂原活化蛋白激酶
  15. Mitogen - activated protein kinase, mapk

    絲裂原活化蛋白激酶
  16. In both cell lines ex - pressing sh2a gene, the cytoplasm pkc activity decreased 40 %, but no apparent alteration was found in mapk, tpk and membrane pkc activity. the proliferation index of transfected cells exhibited an decline in cytometry detection

    L sh的肝癌bel7402細胞及cos7細胞胞漿蛋白中的pkc活性均下降達40 ，胞膜pkc 、胞漿mapk ， 』 fpk活性未見明顯改變，轉染細胞經流式細胞儀檢測增殖指數有所下降。
  17. The protection of p38 mapk inhibitor against hepatic injury in septic rats

    抑制劑對膿毒癥大鼠肝損傷的保護作用
  18. Most of mapk upstream molecules are the molecular marker of the receptivity of endometrium during implantation period, for instance, evidence suggests egf and its receptor egfr may play a role in rendering the endometrium receptive to embryo implantation. the temporal and spatial expression of ley oligosaccharide in the uterus suggests that this factor may be involved in cell - cell communication between the uterus and blastocyst during implantation period

    在植入期的子宮內膜， mapks的上游信號分子大多是其接受態的標志分子，如egf及其受體egfr ，可作為胚泡與子宮內膜間的信息傳遞物質，代替雌激素促進子宮上皮細胞分化、增生，誘導胚胎著床。
  19. Protecting effects of p44 42 mapk signal transduction pathway on hepatocytes in ischemic preconditioning

    絲裂原激活蛋白激酶信號通路在肝臟缺血預處理細胞保護效應中的作用
  20. However, there are limitied documents about receptor signal transduction within uterine endometrium during implantation. the factors regulating endometrial receptivity remain poorly understood. the objective of this dessert is to investigate mapk ' s expression and location in differnt days of pregnancy, as more important, we try to elucidate the relation of mapk and the receptivity of endometrium

    本課題組經研究還發現lewis ~ y寡糖在植入中呈階段特異性表達，可影響其他如lif 、 egf 、 fn （纖連蛋白）和mmps （基質金屬蛋白酶）等因子的表達，推測其可能作為一種信息分子經某種轉導途徑（例如mapk ）而發揮作用。
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