multiple sequence alignment 中文意思是什麼
multiple sequence alignment
解釋
多重序列比對-
To deal with the question that how we can guarantee the dna sequences which are stored in the personal dna database are anonymous, that no one can find out whom a special dna sequence is collected from, this paper get a new method ? savior, by improve dnala ( dna lattice anonymization ), which is a method settling this question. savior replaces the multiple alignment in dnala with pairwise alignment between every tow sequences, and replaces the greedy algorithm in dnala with stochastic hill - climbing. for doing this, it can save the time for data pretreatment, and add the precision of classing
針對個人dna數據的隱私保護問題，即:如何保證無法將存儲在數據庫中的dna序列信息與其提供者的個人身份信息（如:姓名，身份證號碼等）聯系起來，本文對一種新近開發的隱私保護方法? dnala （ dnalatticeanonymization ）進行了改進，在數據預處理階段，用兩兩雙序列比對代替了原演算法中的多序列比對，在不降低處理精度的情況下減少了數據預處理所耗費的時間;用隨機爬山法代替了原演算法中的貪心策略，增加了演算法後期處理的精度，從而形成了一種新的演算法? savior 。 -
Gfral was high expressed in e. coli after iptg induction. by ni2 + chelation affinity chromatography, the purified recombinant gfral protein were obtained. based on the evolutionary trace method, multiple sequence alignment and dendrogram construction were then carried out by the clustalx program and constructed a phylogenetic tree from a multiple sequence alignment for a protein family
2 . gdnf的表達及其對pc12基因工程細胞的影響用本教研室已構建好的表達質粒pet一gdnf轉化大腸桿菌bl21 （ de3 ） ，經lmmipto誘導gdnf表達，並在niz氣nta柱上進行純化，稀釋復性后，純度達90 %以上。 -
In this dissertation, the following experiments are conducted : firstly, cloning of hpab - gene, i ) the amino acids sequences of 23 animal - peptide antibiotics were analyzed by multiple sequences alignment method and a pair of degenerated primers were designed according to the consensus sequence derived from mature peptides of some beta peptide antibiotics
人源肽抗生素hpab -的基因克隆：對動物23種型肽抗生素的氨基酸序列進行對比，選擇部分相似性較高的序列，分析其成熟肽的結構特點，抽提型肽抗生素的一級結構特徵，並以此為基礎設計簡並引物。 -
Solving the multiple sequence alignment problem based on simulated annealing algorithm
多序列聯配問題的模擬退火求解 -
Among these tools, multiple sequence alignment ( msa ) is the most important because msa is central to most bioinformatics techniques
因為其它的許多生信息學工具都是以多序列對齊為基礎的。 -
Pairwise and multiple sequence alignment algorithms of bioinformaics are studied in this paper. the main contents and production can be briefly summarized as follows : 1
本文研究了生物信息學中的雙序列和多序列比對演算法，主要研究內容和取得的成果如下： 1 -
5. in biology field, clustal is one of the most popular multiple sequence alignment software. when large numbers of sequences are aligned at one time, the time complexity of clustal algorithm is very big and it is not suit for vast sequences
Clustal程序是生物學界通用的多序列比對軟體之一，隨著同時進行比對的序列數據量的增加，其時間復雜度急劇增加，該程序無法滿足大規模的序列數據比對。 -
A solution applying genetic algorithm to multiple sequence alignment was presentd after multiple sequence alignment research actuality was analysized. in this solution, some genetic strategies was designed for multiple sequence alignment problem. for example, coding, initial population, fitness function and the operations of natural selection, crossover and mutation
基於多序列比對研究現狀的分析，提出一種基於遺傳演算法的多序列比對解決方法，設計並實現了序列比對問題的遺傳編碼，初始群體生成方式，適應度函數計算以及選擇、交叉和變異三種重要遺傳操作的方式。 -
4. because genetic algorithm obtains local optimal solution at times, an approach was advanced that incorporates simulated annealing into genetic algorithm to improve the performance of genetic algorithm. an annealing operation is added and can improve the convergence rate evidently in multiple sequence alignment
針對遺傳演算法容易陷入局部最優解的缺點，提出模擬退火演算法與遺傳演算法相結合的思想，在遺傳操作中加入退火操作，可明顯提高多序列比對進化後期的收斂速度。
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