nmda 中文意思是什麼

nmda 解釋
n-甲基-d-天冬氨酸
  1. Nmda receptors contribute to synaptic transmission in anterior cingulate cortex of adult mice

    受體參與小鼠的前額扣帶回的神經突觸傳遞
  2. Forebrain nmda receptors contribute to neuronal spike responses in adult mice

    成年小鼠前腦nmda受體參與神經元的動作電位發放
  3. The change of the gene expression of nmda receptor subunits in rat hippocampus after scalding

    天冬氨酸受體亞型基因表達的變化
  4. But people with schizophrenia do not respond this way, which implies that their brain circuits reliant on nmda receptors are out of kilter

    不過精神分裂癥患者的反應就不同,顯示他們腦中依賴nmda受體的線路處于不正常狀態。
  5. Pka agonist 8 - br - camp ( l0 # moi / l ) had no effect on lnmda and b ( 10 - ' momi ) suppression of nmda - evoked current

    即rp七amps也具有抑制inmda峰值和翻轉b對inmda快速抑制效應的作用。
  6. Many laboratories have demonstrated that nmda - receptor blockade reduces infarct volume in both lissencephalic and gyrencephalic animal models of transient or permanent focal ischemia

    許多實驗室都證明阻斷了nmda受體能降低短暫或永久性局灶性缺血模型的梗死面積。
  7. Dr kalev said a " very important " brain receptor, called an nmda receptor, appeared to be necessary for the process

    卡萊弗博士說大腦中的「門冬氨酸受體」在這一過程中起了「十分重要」的作用。
  8. Dr kalev said a & quot; very important & quot; brain receptor, called an nmda receptor, appeared to be necessary for the process

    卡萊弗博士說大腦中的「門冬氨酸受體」在這一過程中起了「十分重要」的作用。
  9. " pathways by which memory is laid down are unclear, but nmda receptor is critical in this process, " dr kalev said

    卡萊弗博士說: 「目前有關記憶儲存的『路徑』尚不清楚,但門冬氨酸受體在這一過程中起了關鍵性作用。 」
  10. A c a2 + / calmo dul in - dep endent pro te in kinas e i i ( c amkii ) antagoni st kn - 6 2 ( 5x l0 - ' mol / l ) presented in the intemal solution had no significan effect on the current peaks induced by extracellular nmda ( l0 # mol / l ), but prevented the inhibitory effect of b on inmda " these results indicate that gcs have rapid, reversible idebitory effects on lnmda intracellular application of b thiough microelectrode had no effect on inmda, howevet, extracellular application of b or b - bsa suppressed peaks of inmda : all these denote b exerts its influence on nmda receptor by cytoplasm membrane mechansms, which is naxnely rapid, nongenomic mechhasms

    加有快速、可逆的。非濃度依賴性抑制作用。通過微電極將b直接導入細胞內, inmda不受影響,而胞外給予b或besa , inmda減小,提示b對nmda受體的調控通過膜機制產生,這種作用與經典的基因組機制不同;因為廣譜激酶抑制劑和特異的pka抑制劑均可翻轉b的抑制效應, camk11抑制劑也可阻斷b的效應,而這些激酶抑制劑本身對inmda即有強烈的抑制作用: pka激動劑本身對inmda無明顯作用,也不影響b對l 。
  11. Thus, nmda receptor dysfunction, by itself, can explain both negative and cognitive symptoms of schizophrenia as well as the dopamine abnormalities at the root of the positive symptoms

    因此, nmda受體本身功能的缺失,就能解釋精神分裂的負性以及認知方面的癥狀,同時也能解釋造成正性癥狀的多巴胺失調。
  12. Resent studies demonstrate that, such as gabaar1 subunit of gaba receptor, ka2 and glur6 subunit of ka receptor, there are some functional regions in that of c terminus which can regulate these subunits targeting to the cell membrane surface. while little was known whether nmda receptor ' s nr2b subunit has the similar domains

    最近有一些研究報道,許多突觸受體如gaba ( b )受體rl亞單位、 ka受體的kaz和glur6亞單位以及孤兒受體腿亞單位的胞內區,存在有影響受體運輸到細胞膜的功能區,但是尚未有對于nmda受體的nrz亞單位膜運輸的報道。
  13. In vitro injury models of brain slice ( ogd and nmda insult ) and primary neuronal cultures ( nmda insult ) oxygen / glucose deprivation ( ogd ) - induced injury of rat hippocampal slice in vitro the rat hippocampal slices prepared were allowed to recover in the normal artificial cerebrospinal fluid ( acsf ) bubbled with gas mixture of 95 % o2 + 5 % co2 for 1 h, then they were thansfered to glucose - free nacsf which was bubbled with gas mixture of 95 % n2 + 5 % co2. after treatment with ogd, the slices were placed into 2 % ttc solution in dark and incubated at 37 * cfor 1h. the slices were weighted and a 50 : 50 mixture of ethanol / dimethyl sulfoxide was then added to extract the formazan in dark for 24 h

    離體腦片損傷模型( ogd和nmda )及原代培養神經元nmda損傷大鼠離體海馬腦片缺氧缺糖( ogd )損傷大鼠離體海馬腦片制備后,在通氧混合氣的正常腦脊液( nacsf )中恢復60min ,然後移入通氮混合氣的無糖腦脊液(吵化sf )中缺氧缺糖,取出腦片與2 ttc避光37 』 c溫浴60dll ,染色后根據每克濕重加入20ml抽提液(乙醇:二甲亞礬一50 : 50 ) ,在密閉容器內避光置24h ,測量前搖勻后取200pi至96孔板,在490urn波長,酶標儀測定各孔od值。
  14. Krystal, j. h., et al. " nmda agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders. " harvard rev. psychiatry 7 ( 1999 ) : 125 - 143

    《哈佛評論精神病學》 7 , ( 1999 ) : 125 - 143 ,用於腦病變癥候群中的氨酸鹽能官能障礙和藥物療法的探測劑, n -甲基- d -天冬胺酸酯促效劑和拮抗劑
  15. More precisely, they block the action of a form of glutamate receptor known as the nmda receptor, which plays a critical role in brain development, learning, memory and neural processing in general

    說得更精確些,這些藥物阻斷了一種叫做nmda型的麩胺酸受體,該受體對于大腦的發育、學習、記憶以及一般的神經活動都扮演著舉足輕重的角色。
  16. Yu sp, yeh ch, strasser u, et al. nmda receptor mediated k + efflux and neuronal apoptosis j. science, 1999, 284 : 336

    張錦華,張曉琴,章軍建.迷走神經刺激對戊四氮致癇大鼠丘腦網狀核谷氨酸受體的影響j .中國神經免疫學和神經病學雜志2002 , 9 ( 3 ) : 125
  17. A change in functional properties of the nmda receptors has been invoked as a potential mechanism contributing to the loss of synaptic plasticity during brain maturation. from this, it is important to well understand the structural and functional diversity of nmda receptors in relation to nmda receptor subunit composition and spatial distribution at excitatory synaptic sites during development

    近幾年來,在哺乳動物中樞神經系統中,對離子型谷氨酸受體如何定位到興浙江大學醫學院碩士論文nrzb亞單位的c末端胞內區影響n協da受體裝配、運鈞以及表面表達的分子機制奮性突觸的研究有了長足的發展。
  18. If reduced nmda receptor activity prompts schizophrenia ' s symptoms, what then causes this reduction

    如果說nmda受體活性的下降促成了精神分裂的癥狀,那麼又是什麼原因造成了這種活性下降?
  19. They expressed two kinds of channel activities : burst and cluster, the bigger conductance channels show more cluster opening than cluster opening. the effects of the incitants and agonist on the nmda receptors of the marginal division in the rat striatum is different ( p < 0. 05 )

    2在對青壯年sd大鼠腹腔注射nm [ da受體阻滯劑的實驗條件下,設計並製做了邊緣區毀損( n行d組) 、海馬傘離斷( ff組)等試驗動物模型,並在m 。
  20. Reporting at first time the long - term potentiation ( ltp ) of c - fiber evoked field potentials in spinal dorsal horn and discovering that activation of spinal nmda, nk1 and nk2 receptors is essential for the induction of the spinal ltp

    C纖維誘發電位的長時程增強( ltp ) 。發現激動nmda 、 nk1和nk2受體是誘導ltp的必要條件;自然痛刺激可引起c纖維誘發電位的ltp ,但在正常情況下受到下行抑制系統的抑制。
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