phage peptide library 中文意思是什麼

phage peptide library 解釋
噬菌體肽庫
  • phage : n. 【醫學】噬菌體(= bacteriophage)。
  • peptide : n. 【生物化學】肽;縮氨酸。
  • library : n. 1. 圖書館,圖庫;藏書樓;藏書。2. 叢書,文庫。
  1. Then the biotin - labelled n - peptide interacted with the phage antibody library

    對其研究可能有助於了解成癮機制和有臨床應用價值。
  2. Screening of mimicry peptide of japanese encephalitis virus e protein from phage 15 - mer peptide library

    從噬菌體15肽庫中篩選乙腦病毒糖蛋白模擬肽
  3. One n - peptide - binding scfv clone was selected from the phage antibody library using affinity panning. the target antigen, n - peptide was biotinylated using photobiotin first

    N -肽是一種新發現的神經肽,其n端與阿片肽高度同源,可與阿片肽受體相互作用。
  4. Screening of tnf - mimotopes from c7c phage display peptide library

    表位模擬肽的研究
  5. Methods : a set of oligonucleotide primers were designed and used to amplify the vh and vl gene from anti - hbsag fab antibodies screened from phage antibody library. the products were cloned into puc19 vector and their sequences were analysed. the vh and vl gene fragments were tethered by a peptide linker and a leader sequence coding region, with the leader sequence added at 5 " terminus of each gene ( l - vh - linker - vl ) and designated as l - scfv

    方法以從噬菌體抗體庫中篩選獲得的抗hbsag的fab抗體基因為模板,分別擴增出其輕、重鏈可變區( v _ l 、 v _ h )基因,通過重組pcr方法將輕、重鏈可變區基因用連接肽( gly _ 4ser ) _ 3的編碼序列連接,並引入前導肽編碼序列,構建具有l - v _ h - linker - v _ l結構的單鏈抗體基因。
  6. Construction of murine phage antibody library and selection of n - peptide - binding single - chain antibodies

    小鼠噬菌體抗體庫的構建和n -肽結合單鏈抗體的篩選
  7. In the present paper the application of dna library, phage display random peptide library, phage antibody library, etc. in the research of serodiagnostic reagents and their special values were reviewed

    本文綜述了基因文庫、噬菌體展示肽庫及噬菌體抗體庫技術在血清學診斷試劑研製中的應用及其各自的優點。
  8. On account of vaccination purpose, the neutralizing protection of anti - ns5 antibodies should be tested. ( 3 ) screening antagonistic peptide of ns5 protein a library of phage - displayed disulfide - constrained random peptides was incubated with a plate coated with the recombinant ns5 protein

    ( 3 ) nss蛋白小分子結合膚的篩選:以活性表達的nss蛋白為配基,從噬菌體展示的構象約束性隨機膚庫中篩選相應的配體分子,共進行了4輪篩選。
  9. In this study we screen the phage - epitope library in attempt to predict the receptor recognition site on vegf, identify peptide able to block the interaction of vegf - kdr and find a potent vaccine against tumor angiogenesis by targeting vegf

    [方法]以兩個具有中和vegf活性的抗- vegf單克隆抗體jh121 、 vg189為目標,分別對噬菌體隨機7肽、 12肽庫進行篩選。
  10. Part ii screening of tnfa mimotopes from phage display peptide library : based on the results of screening tnfa binding - peptides, we have tried to use neutral tnfa mcab j1d9 as target to screen tnfa mimotopes from c7c phage display peptide library, which may be another form of antagonist for tnfa, and the mimotopes were identified by sandwich elisa. after 3 rounds of screening, we got 9 phage clones identified as positive clones which can bind with mcab j1d9. we also identified the binding between mimotopes and tnf receptor by competitive elisa, and the results showed strongly binding. the amino acid sequence results shown three different sequences : c - rrpaqsg - c - nkhnrki - c and c - rgmsrki - c

    在對噬菌體環七肽庫進行三輪親和性篩選后,隨機挑選20個噬菌體克隆, elisa鑒定出9個陽性克隆,經dna測序推出三種氨基酸序列: c - rrpaqsg - c 、 c - nkhnrki - c和c - rgmsrki - c ,其中優勢克隆序列為c - rrpaqsg - c ;鑒定結果顯示陽性克隆能夠與tnf受體結合,並且能夠阻斷tnf與受體的結合,提示篩選得到的環七肽克隆展示肽具有tnf的抗原性及與tnf受體結第一軍醫大學顧士學位論文合的特性,為tnfa表位模擬肽。
  11. Our research can be divided into the following four parts : part i screening of tnfa - binding peptide from phage display peptide library : the tnfa binding - peptides were screened from c7c phage display peptide library by using rhtnfa as target protein and identified by sandwich elisa, for exploring whether the binding - peptides can be used as antagonist of tnfa or not

    篩選tnf小分子模擬肽及結合肽對于tnf研究具有重要的意義。本研究包括以下四個方面: 1 、 tnf結合肽的研究:以rhtnf為靶對噬菌體環七肽庫進行篩選,以尋求可拮抗tnf活性的小分子短肽。
  12. Immunoscreening of phage random peptide library with sera from patients with schistosomiasis japonica

    日本血吸蟲病患者血清對噬菌體隨機7肽庫的免疫篩選
  13. Identification of the epitope of prrsv n protein monoclonal antibody with phage displayed random peptide library

    蛋白單克隆抗體識別的表位
  14. Identification of epitope recognized by monoclonal antibody with phage - displayed random peptide library

    噬菌體隨機肽庫在確定單抗識別表位中的應用
  15. Advancement phage display peptide library technology

    噬菌體展示肽庫技術應用的研究進展
  16. Construction and application of phage display random peptide library

    噬菌體隨機展示肽庫及其應用
  17. Radiolabeling of filamentous phage peptide library with 99mtc and its biodistribution in normal mice

    標記絲狀噬菌體肽庫及其在正常小鼠體內的分佈
  18. These phage display peptides may be the tnfa mimotopes. part iii specific c7c tnfa mimotope phage clone as target for screening of tnfa specific binding - peptides from 12mer phage display peptide library : by using the specific c7c tnfa mimotope as target, we developed a novel approach for screening phage peptide library targeting specific phage display peptides. we used c7c tnfa mimotope phage clone lcs - 7 ( c - rrpaqsg - c ) as target to screen 12mer phage peptide library and identify the positive clones by phage elisa

    3 、以特異性噬菌體克隆為靶篩選肽庫的研究? ?一種肽庫篩選新方法的建立:為了深入研究細胞因於與配基(受體或抗體)相互作用的關鍵殘基及其空間構象,在上述研究基礎上,我們以tnfa表位模擬肽克隆為靶篩選噬菌體十二肽庫,找尋與之結合的tnfa結合肽噬菌體克隆;並以此拓寬了噬菌體肽庫的應用范圍。
  19. Phage display random peptide library is a kind of polypeptide library developed by filamentous bacteriophages

    摘要噬菌體隨機展示肽庫是一類利用絲狀噬菌體發展起來的多肽文庫。
  20. After 3 rounds of screening, 10 of 20 clones were identified as positive clones and all the 10 phage clones sharing the same amino acid sequence : ehmaltypfrpp, and these positive 12mer phage clone peptide can bind with tnfa specifically. the results suggests that this method is very specific and simple for screening of binding epitope to small peptide molecule from phage display peptide library

    在以噬菌體環七肽tnfa模擬肽克隆刁k naqsoc )為靶對噬菌體隨機十二肽庫進行h輪篩選后,挑取20個克隆,經elisa鑒定有10個克隆均與t 』 nfa結合,測序結果顯示它們均為同一氨基酸序列: ehmaltypfrpp 。
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