phosphodiesterase 中文意思是什麼
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Protein kinase a is camp - dependent kinase, one of the most important signal transduction pathways, plays a pivotal role in growth, differentiation, tumor occur, cell cycle control, etc. pka activators such as camp, 8 - br - camp or phosphodiesterase ( pde ) inhibitor isomethyl butyl xanthine ( imbx ) or purified pka catalytic subunit all can inhibit germinal vesicle breakdown ( gvbd ) and meiotic maturation in mouse oocytes, also in xenopus oocytes
蛋白激酶a （ proteinkinasea ， pka ）是依賴于camp的絲蘇氨酸蛋白激酶，是重要的信號傳導途徑之一，廣泛參與許多生命過程，包括生長、分化、腫瘤發生、細胞凋亡、細胞周期調控等。以小鼠卵母細胞為實驗對象，給予pka激動劑camp 、 8 - br - camp或磷酸二酯酶抑制劑imbx （ isomethylbutylxanthine ）均可抑制小鼠卵母細胞的胚泡破裂及減數分裂成熟。 -
" the concept is that systemic sclerosis, which is a severe disease characterized by systemic fibrosis, is at the beginning mainly a vascular disease, and we hypothesize that using major vascular drugs ( calcium channel blockers, endothelin antagonists, prostacyclins, phosphodiesterase inhibitors, etc. ) from the beginning and at appropriate dosage may interfere with the fibrotic process which seems secondary, " dr
「從概念上講，系統性硬化是一種以系統性的纖維化變性為特徵的嚴重疾病，早期主要表現在血管性的病變，因此我們推測早期、適量地應用主要作用於血管的藥物（如鈣離子阻斷劑，內皮素拮抗劑，前列環素，磷酸二酯酶抑制劑等）可能可以干預似乎是繼發發生的纖維化過程。 」 -
" the concept is that systemic sclerosis, which is a seere disease characterized by systemic fibrosis, is at the beginning mainly a ascular disease, and we hypothesize that using major ascular drugs ( calcium channel blockers, endothelin antagonists, prostacyclins, phosphodiesterase inhibitors, etc. ) from the beginning and at appropriate dosage may interfere with the fibrotic process which seems secondary, " dr
「從概念上講，系統性硬化是一種以系統性的纖維化變性為特徵的嚴重疾病，早期主要表現在血管性的病變，因此我們推測早期、適量地應用主要作用於血管的藥物（如鈣離子阻斷劑，內皮素拮抗劑，前列環素，磷酸二酯酶抑制劑等）可能可以干預似乎是繼發發生的纖維化過程。 」
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