phosphorylation 中文意思是什麼

Effect of filamin - c on extracellular signal - regulated kinase phosphorylation mediated by 1a - adrenergic receptor in hek293 cell

腎上腺素受體介導細胞外信號調節激酶磷酸化作用的影響

According to the research of physiological and biochemical indicators or index, components of soluble proteins, substrate protein of phosphorylation and the activity of protein kinase in low - temperature stress in the leaves of brassica oleracea l., we tried to find the law of the physiological and biochemical response of brassica oleracea l. leaf to low temperature. at the same time, discussion on the signal transduction can also provide further evidences for revealing the mechanism of low - temperature stress. the results are showed as follows : malondialdehyde ( mda ), superoxide dismutase ( sod ), ascorbate peroxidase ( asp ) and peroxidase ( pod ) activities were changed greatly after 0 ~ 30min ' s treating with low temperature

本文以甘藍葉片為材料，通過對低溫5脅迫下甘藍生理生化指標、可溶性蛋白組分以及磷酸化底物蛋白、蛋白激酶活性的研究，以期找出甘藍葉片對低溫脅迫的生理生化響應規律，為甘藍露地越冬栽培防範寒害提供理論指導，同時對低溫脅迫下甘藍逆境信號傳導進行了探討，從而為徹底弄清低溫脅迫機理提供進一步的證據，研究的主要結果如下：丙二醛含量（ mda ） 、超氧化物歧化酶（ sod ） 、抗壞血酸過氧化物酶（ asp ）和過氧化物酶（ pod ）活性在低溫處理0 30min發生顯著變化，低溫處理3min后，甘藍葉片內mda含量基本沒有變化，處理5min時出現第一個峰值，達到對照的104 . 10 ， 10min出現低谷，僅為對照的86 . 27 ，隨后再次上升， 30min時超過第一峰值，為對照的113 . 93 。

Effect of cell adhesion on vasodilator - stimulated phosphoprotein phosphorylation

細胞黏附對血管擴張刺激磷蛋白磷酸化的影響

The phosphorylation of cdc2 tyr15 was increased with the age in germ cells 3. p70s6k was mainly in spermatocyte, sperm cell and sperm

3 . p70s6k主要在精母細胞、精子細胞及精子中有所表達，在不同發育階段細胞內的分佈不同。

In rat hippocampal slices, tbs induced phosphorylation of p21 - activated kinase ( pak ) and its downstream effecter cofilin, signaling proteins that enable actin filament growth

在鼠海馬切片中，短暫快速脈沖刺激導致蛋白激酶21的磷酸化，在它的下游區產生了cofilin ，一種能使肌動蛋白絲生長的信號蛋白。

The enzyme digest analysis shows that the arm repeats of c - terminal are conceivably conservative domain. in arc1 protein, there are some active sites including n - glycosylation sites, camp - and cgmp - dependent protein kinase phosphorylation sites, protein kinase c phosphorylation sites, casein kinase ii phosphorylation sites, tyrosine kinase phosphorylation sites, n - myristoylation sites, amidation sites and leucine zipper pattern. it probably take part in the signaling process of self - incompatibility

同時在arc1蛋白質中還發現了拉鏈結構和多個磷酸化位點，包括camp和cgmp依賴的蛋白激酶磷酸化位點、蛋白激酶c磷酸化位點、酪蛋白激酶磷酸化位點、酪氨酸激酶磷酸化位點、糖基化位點等，拉鏈結構為arc1蛋白之間及與其它蛋白的相互作用提供了可能，而磷酸化位點是arc1參與信號傳導過程所必需的。

Correspondingly, the egf binding affinity of surface egfr and the tyrosine auto - phosphorylation of immuno - precipitated egfr were also enhanced in gntv - s / h7721 cells and reduced in gntv - as / h7721 cells

Egfr的信號通路主要有兩條，一是ras - raf - mek一mapk經典途徑，另一條是新發現的pi一3k一pkb途徑。

The combination of meja and fc did not show significant additive effect on enzyme activity. 3. phosphorylation and dephosphorlation of pm h ^ - atpase after treatments of meja and fc 1 ) in vitro, phosphatase inhibitors, okadaic acid and cantharidin, enhanced meja - induced increase of the enzyme activity to 60 % and 50 %, respectively

Tllrase過程中可能發生的磷酸化和去磷酸化作用1 ）磷酸酶抑制劑斑螫素、崗田酸可以增強meja對酶的刺激作用，崗田酸的效應較強，而斑鰲素的作用略弱，增幅分別為60和50左右。

In thl1 gene, there are some famililar enzyme digest sites including bamh i, hind, sac i and sal i. the sequence of thl1l from brassica oleracea l. shows 99 % identity to the sequence of thll from brassica napus l. there are some phosphorylation sites and an active site of thoiredoxin h members consisting of cppc in thll protein

甘藍和油菜thl1基因序列有5個堿基的差異，而氨基酸僅有2個氨基酸的變異，同源性達99 。在thl1蛋白的氨基酸序列中發現了一個硫氧還蛋白家族的活性位點（ cppc ）和多個磷酸化位點。

Focal adhesion kinase tyrosine phosphorylation promotes rat hepatic fibrogenesis and its possible mechanism

黏著斑激酶酪氨酸磷酸化促大鼠肝纖維化形成及其可能機制

Part ii effects of gnt - v on the phosphorylation and activity of egfr signaling molecules in h7721 cells modification of the n - glycan structure and function of egfr by the transfection of different gnt - v cdnas may lead to the alterations of the phosphorylation and activity in the downstream molecules of signal transduction

Gntv一s / h7721細胞p42 / 44mapk的磷酸化也較mock細胞增強，而gntv一as艦7721細胞則減弱，表明egfr的這兩條信號通路中信號分子的磷酸化或活力都受gnt一v的影響。

We also found that p1206 " 1 can be easily phosphorylated at tyrosine by epidermal growth factor ( egf ). tyrosine phosphorylation of p ! 20ctn strengthened bel - 7404 cells malignant behavior, and p120ctn translocated into nucleus

我們還發現，芒果貳有降低pi20ctn磷酸化的作用，其結果是bel一7404細胞粘附能力有所增強，遷移能力降低。

There is a relationship between catenin phosphorylation, translocation and tumoregenesis, further more, in this relationship, cell signaling cascade and mitogen and their receptors are involved. base on these evidences, people are trying to disturb the key molecules in this signaling cascade for anti - tumor purpose

表皮生長因子（ egf ）能使p120 ~ （ ctn ）酪氨酸磷酸化，磷酸化使bel - 7404細胞的粘附能力降低而遷移行為增強； p120 ~ （ ctn ）在細胞內的分佈出現明顯的核內轉位， -連環蛋白也出現相似的變化。

Jak2 regulats gene function by the phosphorylation and translocation to nuclear of its substrate stat

Jak2通過使其下游底物stat磷酸化並且轉位至胞核，發揮其對基因的調控作用。

In xenopus embryonic extracts camp concentration and pka activity also oscillations accompany with the cell cycle, low in mitosis and increased during m / g1 transition, keep high until next mitosis, and the mechanism concern with the cdc25 phosphorylation state and cyclin b concentration. mouse fertilized egg is the most simple and natural model for cell cycle that near to human, but little is know about pka on mpf also pka on mitosis

通過對非洲爪贍胚胎細胞周期的研究發現jka活性也隨細胞周期變化而波動，在m期出現時pka活性下降，而m間期轉換時pka活性達最大值，一直維持高值直到下一個m期出現，其對mpf活性調節與cdc25磷酸化狀態及周期素b表達有關。

It is divided to extracellular and intracellular part by transmembrane domain. there are 13 n - glycosylation sites, 20 protein kinase c phosphorylation sites, 28 casein kinase ii phosphorylation sites, 4 tyrosine kinase phosphorylation sites and 15 n - myristoylation sites in the extracellular part of bt - r3 protein. an integrin recognition sequences rod lies in intracellular part of bt - r3 protein

跨膜區域（ tmd ）將它分為胞內和胞外兩個部分，它的胞外有13個潛在的糖基化位點， 20個蛋白激酶c的磷酸化位點， 28個酪蛋白激酶的磷酸化位點， 4個酪氨酸酶的磷酸化位點， 15個豆蔻（十四烷基）酰化位點；它的胞內有1個整合蛋白（ integrin ）識別位點。

Hypoglycemic effects of sodium metavanadate in diabetic mice and its effect on glucose phosphorylation

偏釩酸鈉降低糖尿病小鼠血糖及其對葡萄糖磷酸化的影響

In this experiment, the inside - out configurations of patch - clamp techniques were used to study the physiological properties, phosphorylation modulation and temperature sensitivity of bkca channel in hypothalamic neurons of newborn sd rats. objective : studing the physiological properties. phosphorylation modulation and temperature sensitivity of calcium - activated potassium channels ( bkca ) in hypothalamic neurons of newborn sd rats in order to elucidate the role of bicca channel in temperature regulation

本實驗研究了sd乳鼠下丘腦神經元大電導鈣激活鉀通道（ large - conductanceca ~ （ 2 + ） - activatedpotassiumchannels ， bk _ （ ca ） ）特性的溫度依賴性及磷酸化對其溫度依賴性的影響，以求為體溫調節機制的最終闡明提供重要的理論依據。

Huangyal4 was complete nucleotide sequence of 1 854 bp with a nucleotide orf ( 1575 bp ), which encoded a protein consisting of 524 aa with molecular weight of 62. 2 kda and pi of 8. 96. strongly basic ( + ) amino acids, strongly acidic ( - ) amino acids, hydrophobic amino acids and polar amino acids of the protein were 13. 74 %, 11. 64 %, 36. 45 % and 22. 70 % respectively, and predicted secondary structure of the protein revealed many conserved domains such as n - glycosylation site, protein kinase c phosphorylation site, casein kinase ii phosphorylation site, n - myristoylation site, camp - and cgmp - dependent protein kinase phosphorylation site, tyrosine kinase phosphorylation site and a cytochrome p450 cysteine heme - iron ligand signature which was typical of cytochrome p450. a - helix and b - sheet of the protein is 47. 7 %, 45. 0 % respectively

Huangya14 ）為材料分離克隆到一個細胞色素p450基因，命名為bccyp86mf5 ， cdna全長1854bp ，含1575bp的完整開放閱讀框，編碼524個氨基酸，其編碼蛋白質的分子量為61 . 2kda 、等電點為8 . 96 ；堿性氨基酸、酸性氨基酸、疏水氨基酸和極性氨基酸分別占總氨基酸的13 . 74 、 11 . 64 、 36 . 45和22 . 70 ；二級結構預測包括n -糖基化位點、依賴于camp和cgmp的蛋白激酶磷酸化位點、蛋白激酶c磷酸化位點、酪蛋白激酶磷酸化位點、酪氨基酸激酶磷酸化位點、 n -豆蔻酰化位點和細胞色素p450的典型區域，半胱氨酸亞鐵血紅素配體信號區等， -螺旋和-折疊分別佔47 . 7 、 45 . 0 ；與bccyp86mf1基因的氨基酸序列同源性達到95 . 2 ，與擬南芥cyp86c4的達到85 . 9 。

Changes of phosphorylation states of cx43 protein in chinese hamster lung cells induced by sio

二氧化硅致肺成纖維細胞連接蛋白43磷酸化改變的研究