protein isoform 中文意思是什麼
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An unusual rice calmodulin isoform, oscam61, was first obtained in our lab, which contains an n - terminal cam domain and a c - terminal basic extension with a potential prenylation site. in vitro activity assays confirm oscam61 as a functional calmodulin. using the green fluorescent protein ( gfp ) as a visual marker, we further studied subcellular localization of oscam61 in stably transformed tobacco cells
利用綠色熒光蛋白（ greenfluorescentprotein ， gfp ）作為標記，研究了oscam61在煙草細胞中的定位， gfp - oscam61融合蛋白（具有開放的異戊烯化修飾位點）定位於細胞質膜和細胞器膜上，而oscam61 - gfp （異戊烯化修飾位點被gfp封閉）定位於細胞核的核質中。 -
It may have a preventional function from alzheimer ' s disease. molecular biological studies are shown that apoe isoform has a isoform - specific role to neurodegeneration. apoe3 and apoei aid to sustain the stabilization of cytoskeleton protein tau, while apoe4hyperphosphorylates tau to destabilize the microtubule protein, which will make neurocyte easy to form neurofibrillary tangles in ad
分子生物學研究發現， apoe異構體對神經細胞退化表現出異構體特異作用， apoe _ 3和apoe _ 2有助於維持微管的穩定性，而apoe _ 4則使tau蛋白超磷酸化，破壞微管的穩定性，使神經細胞易於形成神經纖維纏結。 -
The newly identified gene, nyd - sp27 has structural similarity to an isoform of phospholipase c. nyd - sp27 was expressed endogenously in human pancreatic - duct cells and upregulated in cystic fibrosis. researchers has proved that suppression of the gene resulted in augmentation of phospholipase - c - coupled calcium - ion release and protein kinase c activity, improvement in the amount of mutated cftr reaching the plasma membrane, and thus restoration of pancreatic anion secretion
Nyd - sp27內源性表達在人體的胰腺導管上皮細胞，並在囊性纖維化時表達增高，顯示該基因可能與病變有關。研究人員發現通過抑制該基因在人體囊性纖維化胰腺導管細胞中的表達，可以糾正缺陷的胰腺陰離子分泌。 -
Construction and expression of a new human growth hormone isoform - gst fusion protein
人新的生長激素異形體基因的克隆及其在大腸桿菌中的表達
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