protein kinase a 中文意思是什麼

protein kinase a 解釋
蛋白激酶a
  • protein : n. 【化學】朊，蛋白（質）。
  • kinase : n. 【生物化學】激酶。
  • a : an 用在以母音音素開始的詞前〉 indefinite art 1 〈普通可數名詞第一次提到時，冠以不定冠詞主要表示類...
  1. Bovine sperm extract or sr2 + - induced ca2 + oscillations in mii oocytes and distribution of protein kinase c a ( pkc a ) in both mil oocytes and early embryos were not differed between young and old mice. electrofusion rates were equivalent among 9 types of gv - cytoplast complexes constructed by gv exchange between 6 - 8 - week - old mice and 6 - 8 - week - old, 3 - month - old, 6 - month - old, 9 - month - old and 12 - month - old mice respectively

    6 - 8周齡小鼠gv期卵母細胞分別與6 - 8周齡、 3月齡、 6月齡、 9月齡和12月齡小鼠gv期卵母細胞進行gv互換所形成的9種gv -胞質體復合體的融合率和9種重組卵母細胞的成熟率並不因小鼠年齡的增長而有所改變。
  2. Protein kinase a is camp - dependent kinase, one of the most important signal transduction pathways, plays a pivotal role in growth, differentiation, tumor occur, cell cycle control, etc. pka activators such as camp, 8 - br - camp or phosphodiesterase ( pde ) inhibitor isomethyl butyl xanthine ( imbx ) or purified pka catalytic subunit all can inhibit germinal vesicle breakdown ( gvbd ) and meiotic maturation in mouse oocytes, also in xenopus oocytes

    蛋白激酶a （ proteinkinasea ， pka ）是依賴于camp的絲蘇氨酸蛋白激酶，是重要的信號傳導途徑之一，廣泛參與許多生命過程，包括生長、分化、腫瘤發生、細胞凋亡、細胞周期調控等。以小鼠卵母細胞為實驗對象，給予pka激動劑camp 、 8 - br - camp或磷酸二酯酶抑制劑imbx （ isomethylbutylxanthine ）均可抑制小鼠卵母細胞的胚泡破裂及減數分裂成熟。
  3. These include phototropism, light - driven chloroplast movements and stomatal movements. the phot i gene of arabidopsis encodes an autophosphosphorylating protein kinase that functions as a photoreceptor for phototropism in response to low - intensity bl. up to now

    在高等植物中，藍光調控多個重要生理反應過程，其中包括下胚軸的向光反應、葉綠體在光下的重新分佈和氣孔的開放等。
  4. Molecular cloning and expression analysis of a serine threonine protein kinase gene in upland cotton

    蘇氨酸激酶蛋白基因的克隆與表達分析
  5. Introduction wnk ( with no lysine kinase ) kinases belong to a novel serine / threonine protein kinase family

    前言wnk激酶是一個新的蛋白激酶家族，是withnolysinekinase的縮寫。
  6. Protein kinase b ( pkb, also named kinase akt ) is newly found as a ser - ine / threonine protein kinase

    Pkb akt2在卵巢癌、胰腺癌細胞中過表達， pkb akt3在大腦和睪丸中表達。
  7. The elicitor of this pathway is ca2 +, ca2 + binds to sos3, which leads to interaction with sos2, a ser / thr protein kinase of 446 amino acids, and activated the kinase. the transcription and post - transcription of sosl, an putative na + / h + antiporter on the membrane is controlled by the sos3 - sos2 complex

    這條途徑的起始為外界高鹽刺激使細胞內ca ~ （ 2 + ）水平發生變化， ca ~ （ 2 + ）作為第二信使與sos3結合，然後導致sos3與sos2相互作用激活sos2的激酶活性，形成sos2 - sos3激酶復合體。
  8. Predicted tertiary structure showed that thl2 protein possessed a domain, and the srk - binding site cppc is located in tertiary structure surface, which provided the spacial foundation for thl2 binding srk kinase

    預測的thl2蛋白質高級結構中有一個結構，並且其與srk結合的活性位點cppc位於蛋白質的表面，這為thl2蛋白與srk激酶結合提供了空間上的基礎。
  9. A study on the regulating self - incompatibility of brassica oleracea l. by inhibitor or activitor of protein kinase

    利用蛋白激酶抑制劑和激活劑調控甘藍自交不親和性
  10. They demonstrate that under hypoxic conditions mif activates the cellular stress response enzyme amp - activated protein kinase ( ampk ), which in turn is a key regulator of metabolism protecting against ischemic damage

    他們證實，在缺氧環境下mif激活細胞內應激反應酶腺苷酸活化蛋白激酶（ ampk ） ，它是隨后抗缺血損傷代謝調控的重要元素。
  11. Huangyal4 was complete nucleotide sequence of 1 854 bp with a nucleotide orf ( 1575 bp ), which encoded a protein consisting of 524 aa with molecular weight of 62. 2 kda and pi of 8. 96. strongly basic ( + ) amino acids, strongly acidic ( - ) amino acids, hydrophobic amino acids and polar amino acids of the protein were 13. 74 %, 11. 64 %, 36. 45 % and 22. 70 % respectively, and predicted secondary structure of the protein revealed many conserved domains such as n - glycosylation site, protein kinase c phosphorylation site, casein kinase ii phosphorylation site, n - myristoylation site, camp - and cgmp - dependent protein kinase phosphorylation site, tyrosine kinase phosphorylation site and a cytochrome p450 cysteine heme - iron ligand signature which was typical of cytochrome p450. a - helix and b - sheet of the protein is 47. 7 %, 45. 0 % respectively

    Huangya14 ）為材料分離克隆到一個細胞色素p450基因，命名為bccyp86mf5 ， cdna全長1854bp ，含1575bp的完整開放閱讀框，編碼524個氨基酸，其編碼蛋白質的分子量為61 . 2kda 、等電點為8 . 96 ；堿性氨基酸、酸性氨基酸、疏水氨基酸和極性氨基酸分別占總氨基酸的13 . 74 、 11 . 64 、 36 . 45和22 . 70 ；二級結構預測包括n -糖基化位點、依賴于camp和cgmp的蛋白激酶磷酸化位點、蛋白激酶c磷酸化位點、酪蛋白激酶磷酸化位點、酪氨基酸激酶磷酸化位點、 n -豆蔻酰化位點和細胞色素p450的典型區域，半胱氨酸亞鐵血紅素配體信號區等， -螺旋和-折疊分別佔47 . 7 、 45 . 0 ；與bccyp86mf1基因的氨基酸序列同源性達到95 . 2 ，與擬南芥cyp86c4的達到85 . 9 。
  12. Introduction protein kinase c ( pkc ) is a number of serine / threonine kinase family which play central regulatory roles in a multitude of cellular processes, including cell proliferation, cell cycle progression, differentiation, apoptosis. increasing evidence from studies using in vitro and in vivo systems suggests that pkc is a key regulator of critical cell cycle transitions, including cell cycle entry and exit and the gl and g2 checkpoint

    前言細胞周期是細胞增殖、分化的一個重要過程，它的啟動與進程受到嚴格調控，參與調控的因子不僅包含起正調控作用的細胞周期素（ cyclins ） 、細胞周期蛋白依賴性激酶（ cyclin - dependentkinase ， cdk ） 、還有起負調控作用的cdk抑制因子（ cyclin - dependentkinaseinhibitor ， cki ） 。
  13. Effects of sodium tanshinone a sulfonate on angiotensin - induced cardiomyocyte hypertrophy and expressions of phosphorylated jnk and mitogen - activated protein kinase phosphatase

    和絲裂原活化蛋白激酶磷酸酶1的表達
  14. In n terminal, 3 conserved sequences, wxixgmxgxgkttla, l ( i / v ) ( v / l ) lddv ( w / d ) and sriixttrd xxv are in term of p - loop, kinase 2 and kinase 3a. those are highly identical to the homologous of human ( apaf - 1 ) and namenode ( ced - 4 ). it revealed that tm - 22 encodes a membrane protein with a receptor structure and kinase property and may function in ion flow, phosphorylation and proteins interaction

    Tm一夕基因的編碼蛋白在該區與tm一2有32個氨基酸的差異，主要集中在第10 、 11和12個亮氨酸重復序列中，與tm一2有兩個氨基酸的差異，僅僅是位於第12個亮氨酸重復序列中的767和769兩個位點，這表明:第一， lrr是tm一22基因和tm一2基因編碼蛋白對病毒識別的特異區段;第二， 767和769兩個位點的差異氨基酸是tm一22基因和tm一2基因編碼蛋白對病毒識別的特異位點。
  15. Mpf is a complex that consists of the protein kinase p34cdc2 and the regulatory protein cycli b ; the protein kinase activity of p34cdc2 is strictly dependent on its association with cyclinb. in xenopus laevis eggs the absent of cyclin b, mpf will not be activited

    Ca卜活化p34 」擬的機制第一步是結合cycinb ，並且處于磷酸化狀態，即thr14 、 tyrls和tlirl61都處于磷酸化狀態；第二步是cdc25磷酸酶通過是thr14 、 tyr15脫磷酸化而激活p34 」擬。
  16. Cortactin, a novel member of filament actin binding protein family and the main substrate of non - receptor src protein kinase, plays an important role in the dynamic organization of cell cortex cytoskeleton

    皮層蛋白（ cortactin ）是一種微絲肌動蛋白結合蛋白，它與肌動蛋白纖絲的側面相結合，並直接參與皮層細胞骨架的組建。
  17. C - kit is a receptor tyrosine protein kinase on the cellular membrane, while c - myc is a transcription regulatory factor in the nucleus

    Kit是位於細胞膜上的受體酪氨酸蛋白激酶， myc是位於細胞核內的轉錄調節因子。
  18. The term protein kinase c ( pkc ) stands for a group of at least twelve serine / threconine kinases that are characterized by a high degree of similarity in their catalytic kinase domains and cysteine - rich regions

    前言蛋白激酶c （ pkc ）是一組絲蘇氨酸蛋白激酶，參與多種信號傳導系統。包括細胞分化、生長調控、腫瘤發生和細胞凋亡。
  19. Many cell signal transduction pathways have been discovered in the regulation of apoptotic induction and reduction. mito - gen - activated protein kinase ( mapk ) is a group of particular ser / thr protein kinases which are activated when its conservative thr and tyr residues are both phosphorylated by upstream mapk kinases

    絲裂原活化蛋白激酶（ mapk ）是一群特殊的絲蘇氨酸蛋白激酶，它通過其上游mapkk使其保守的蘇氨酸和酪氨酸殘基雙磷酸化而活化，活化的mapk可轉移到核內，參與基因表達調控。
  20. It possess high homology with those of ck2 ( casein kinase 2 ) a subunits from various species. it is now well established that protein kinase ck2 is a pleiotropic and abiquitous serine or threonine kinase, which is highly conserved during evolution. we obtained the complete cdna sequence of ck2 a via 5 " race

    酪蛋白激酶ck2是目前發現的普遍存在於真核生物中的絲氨酸蘇氨酸型蛋白激酶，進化上具有高度的保守性並參與了多種生理功能的調控，因而克隆它的基因具有重要意義。
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