proximal region 中文意思是什麼
proximal region
解釋
近側區-
The predicated amino acid sequences contain two conserved functional domains : a dna - binding domain ( hmg - box ) and a transactivation domain. the conserved motif of group b homology lies immediate adjacent to c - proximal region of the hmg - box. similar structure and identity of sox2 gene among mammals, birds, amphibians and reptiles suggest that sox2 gene have evolutionary conserved roles
進一步分析表明，已巴灘2編碼的238個氨基酸多膚鏈含有兩個保守的功能區域:位於n端的hmg盒區（ 1一78aa ）和位於c端的轉錄激活區（ 131一236aa ） ，以及一個保守的特徵性b亞族同源區域（ 79一90aa ）與hmg盒區的c端相連。 -
In ovx rats, not only bone mineral density ( bmd ) of lumbar vertebrae in vivo and vitro, but also bmd of femora ( except for r3 region ) and proximal metaphysis ( r1 region ) in vitro decreased obviously ( p < 0. 01 ) ， whose bone loss rates of l5 and l6 were the highest and achieved 13 % ; the trabeculae of ovx rats were few ， fine, and discontinued and there were lacunae on the surface ; in ovx rats, both compressive strength of vertebral bodies and the mechanical properties of femora decreased ; the falling degree of the former was greater ; the maximal compressive power of lumbar vertebrae decreased with 33. 32 %
結果顯示：大鼠卵巢切除后，活體、離體腰椎以及股骨（除r3區） 、脛骨近端干骺端（ r1區）的離體骨密度顯著下降（ p < 0 . 01 ） ，離體l5和l6的骨丟失率最大，達13 % ；骨小梁減少、變細，連接中斷，骨小梁表面有吸收陷窩；腰椎壓縮強度和股骨力學性能均下降，前者更明顯，腰椎最大壓縮力下降率達33 . 32 % 。 -
Trka, the high affinity ngf receptor, contains an intracellular domain with tyrosine kinase activity and an extracellular domain with three tandem leucine - rich motifs flanked by two cysteine clusters in their amino termini and two immunoglobulin - like domains in the more membrane - proximal region
膜外域含有8個亮氨酸的重復區域，其前後分別串聯著一組半胱氨酸殘基，緊挨細胞膜的是兩個c2 -型免疫球蛋白樣區ig和ig ；膜內域為酪氨酸激酶催化活性區。 -
By yeast two - hybrid assay, aes was found to interact with gp130 intracellular region through its conserved q domain. results from the yeast two - hybrid assay, gluthione s - transferase fusion protein pull - down assay and immuno - co - precipitation assay indicated that the q domain of tle1 is capable of binding gp130 intracellular domain, and the intracellular membrane proximal region of gp130 containing conserved boxl and box2 motifs seemed essential for this interaction. to investigate the consequence of this interaction, tle1 - gfp fusion protein expression vector was constructed and co - transfected into nih 3t3 cells with gp130 expression vector
在通過酵母雙雜交分析確定aes通過q結構域與sp130分子胞漿區結合的基礎上，為確定tle1分子是否也能通過保守的q結構域與gp130分子胞漿區結合，我們通過pcr擴增編碼gp130胞漿區與tleq分子不同結構域的cdna ，構建了含有這些不同結構域的酵母雙雜交載體，通過酵母雙雜交分析證實： tle1分子通過其氨基端的q結構域與gp130分子胞漿區近膜段結合。 -
The proximal femur has been amputated and cut in half to reveal an irregular dark red - black hemorrhagic mass in the epiphyseal region
近端股骨已被截肢並切成兩半而在干骺端顯露出一暗紅黑色血腫。
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