receptor complex 中文意思是什麼
receptor complex
解釋
受體復合物-
The degradation of i k b and dissociation from nf - k b complex are essential process for activation of nf - k b. there is no report about whether cck - 8 inhibits nf - k b activity through inhibiting lps - induced degradation of i k b. the present study was designed to observe the regulatory effect of cck - 8 on changes of immune functions induced by lps, the receptor mechanism and signal transduction mechanism involving mapk, stat3 and i k b at different levels including in vivo and in vitro, in order to study its immunomodulatory effect on reversing es and its molecular mechanisms
Ikb的降解、並從w兒b復合物上解離是w4b激活的必需過程。 ccks是否通過抑制lps誘導的ikb降解，從而抑制nf幾b激活尚未見報道。本研究在整體、細胞及分子水平，觀察了ccke對lps引起的免疫功能改變的調節作用，研究了其受體機制及mapk 、 stat3和ikb的信號轉導機制，以探討cck七抗es時的免疫調節作用及其分子機制。 -
The matter that causes constipation of esophagus cancer patient is relatively complex, it is the patient takes food as a result of deglutition difficulty or ache above all decrease, especially the food intake with cellulose high content decreases, food is gender, chemical to the machinery of gastric bowel gender and temperature stimulation are abate, the receptor of gastric bowel mucous membrane is stimulant reduce, peristalsis decreases
造成食道癌患者便秘的原因較為復雜，首先是病人由於吞咽困難或疼痛而進食減少，尤其是纖維素含量高的食物攝入減少，食物對胃腸的機械性、化學性及溫度刺激減弱，胃腸粘膜的感受器興奮性降低，蠕動減少。 -
An array of regulatory proteins have been found, which inhibit the formation of central enzymes involved in early stages of the complement activation pathway. these include membrane cofactor protein ( mcp cd46 ), decay - accelerating factor protein ( daf cd5 5 ), complement receptor 1 ( cr1, cd35 ), as well as cd59, which inhibits formation of the membrane attack complex during later stages. these regulatory factors are widely expressed and abundant on many cells, and in fluids of reproductive system
目前發現，機體多種細胞以及生殖系統的體液中表達和分泌豐富的補體調控蛋白，包括作用於補體活化早期階段的cd55 、 cd46 、 cd35和作用於補體活化終末階段的cd59 ，它們分別通過抑制補體活化過程中關鍵的c3 、 c5轉化酶和抑制形成膜攻擊單位，抵抗補體對自身組織細胞的攻擊。 -
Effective activation of antigen - specific t cells not only requires the first signal transduction through t - cell receptor ( tcr ) binding with peptide - mhc complex on the antigen presenting cell ( apc ), but also needs the second signal, termed costimulation. costimulation critical to the degree and consequence of t cell activation is provided by interaction between soluble factors or cell - surface molecules on the t cell and on the apc
而t細胞的活化除需要t細胞受體（ tcr ）與抗原呈遞細胞（ antigenpresentingcell ， apc ）表面的抗原肽- mhc復合物結合所形成的第一信號外，還需要t細胞和apc表面的其它膜分子結合所提供的共刺激信號（亦稱第二信號或輔助刺激信號， costimulatorysignal ）的參與。 -
Accumulating evidence indicates that nmda receptors are involved in many complex physiological and neuropathological mechanisms, such as neuronal developmental plasticity, long - term potentiation ( ltp ), learning and memory, excitotoxicity and neurodegenerative diseases etc. three gene families that encode nmda receptor subunits have been identified : nr1, nr2a - d, and nr3 subunit
已知nmda受體與許多復雜的生理和病理機制有關，如突觸的可塑性、長時程增強作用（ ltp ） 、學習和記憶、興奮性神經毒性、神經退行性變性疾病等。已克隆到3個編碼nmda受體亞單位蛋白的基因家族，即nr1 、 nr2和nr3 。 -
Complex interactions between classical cytokines and opioids have been found in the nervous system. the neural effects of opioids can be changed by cytokines, while the effects of cytokines can be modulated by opioids. in pha - stimulated human lymphocytes, the opioid receptor antagonist, naloxone, blunted the effect of il - 2
（ 2 ） 200u mlil 2對心肌細胞作用5min即有明顯效應，引起dl dtmax 、 dl和dl dtlnax降低，舒張末期細胞長度縮短，隨作用時間延長，其對心室肌細胞的抑制作用增強。 -
The neurotrophic and morphogenic activities of gdnf are mediated by its interaction with a multicomponent receptor complex formed by the ret receptor tyrosine kinase and a glycosylphosphatidylinositol ( gpi ) - anchored " accessory " receptor, gdnf family receptor alpha - 1 ( gfral )
Gdnf的神經營養作用主要是通過兩類受體亞基介導，即膠質細胞源性神經營養因子受體alpha （ gfr s ）亞基和受體酪氨酸激酶ret亞基。 -
The members of src family are non - receptor tyrosine kinases. their make an important function in a complex network of intracellular signals, such as cell growth, proliferation, transformation, apoptosis, and cell adhesion, migration. the fact that src was discovered as an oncogene suggests that src could closely involvement in cancer
而今， src已發展成為包括九個成員在內的激酶家族，隸屬于非受體酪氨酸激酶，是細胞信號轉導途徑中一類重要的信號分子，調控細胞的生長，增殖，凋亡，細胞黏附與遷移等一系列功能。 -
The latter plays a very important role in the study of the mechanism and dynamics of the recognition. it includes the molecular modeling, confirming the binding sites, the calculation of interactions between receptor and ligand, the docking research of the complex, the calculation of dynamic and thermodynamic properties etc. many theoretical calculation methods are involved, such as quantum chemistry, molecular mechanisms, molecular dynamics, monte carlo method and free energy calculation and so on
其中計算機模擬方法是研究分子識別機制及其動態過程的重要途徑，包括底物及受體分子模型的構建、底物及受體相互作用位點的確定、相互作用力的計算、底物及受體分子的對接及其動態過程的研究、體系熱力學及動力學性質的計算等方面內容。 -
The superfical layers of the cerebral cortex, piriform cortex, dorsal hippocampus, amygdal complex, reticular formation of the brainstem contained some neurons with nk3 receptor - li
在大腦皮質的淺層、梨狀皮質、背側海馬、杏仁核、腦干網狀結構等核團內也含有一定數量的陽性神經元。 -
Because the large conformational changes occurring upon complex formation are frequently confined to the protein surface, especially for the side chains of flexible amino acids arg, lys, asp, glu and met, the locations of the mass centers and the values of radii of these residues are modified for modeling protein surface. this tolerates overlap in some degree between the amino acid side chains on the surfaces of the receptor and the ligand
由於蛋白質表面氨基酸殘基arg 、 lys 、 asp 、 glu和met具有較大的柔性，因此，北京工業大學工學博士學位論文一我們對蛋白質分子表面的這五種氨基酸模型作了修正，調整了殘基球心的位置和半徑的數值，使分子表面的氨基酸殘基在對接時具有一定程度的可交疊性。
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