s-allele 中文意思是什麼
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In addition to avermectins, s. avermitilis produces oligomycin, a strongly toxic compound. gene deletion vector pxl05 was used to disrupt oligomycin polyketide synthase ( pks ) encoding genes ( olma ) in streptomyces avermitilis cz8 - 73, the producer of anthelmintic avermectins b and the cell growth inhibitor oligomycin. olma gene cluster in the chromosome was displaced by deletion allele on the plasmid via double crossover
本研究以產阿維菌素b和寡黴素的阿維鏈黴菌cz8 - 73為出發菌株，構建了基因缺失載體pxl05 ，並將其轉入cz8 - 73中，通過缺失載體和染色體之間的同源雙交換，對染色體上長達90kb的寡黴素聚酮合酶（ pks ）基因簇（ olma ）進行了缺失。 -
Apoe2 binds poorly to the ldlr, and homozygous inheritance of the apoe2 allele is strongly associated with type iii dyslipoproteinemia. apoe2 and apoe4 are associated with hypercholesterolemia and atherosclerosis ( as ). the apoe4 is also associated with higher incidence and earlier age of onset of late onset familial alzheimer ' s disease ( ad ), whereas apoe2 may have the opposite effect
Apoe _ 2與ldlr結合能力很差，與型高脂血癥關聯。 apoe _ 2和apoe _ 4與高膽固醇血癥、動脈粥樣硬化（ as ）等疾病有關， apoe _ 4還是老年癡呆（ ad ）的高發風險因子，而apoe _ 2則對預防老年癡呆病的發生具有積極作用。 -
Our results showed as follows : 1 ) the spl and rsal polymorphisms of the collagen type 1 alpha 1 ( col1 al ) gene, the - 174g / c promoter polymorphism of the interleukin - 6 ( il - 6 ) gene, the asn363ser polymorphism of the glucocorticoid receptor ( gr ) gene, and the t ? c polymorphism in intron 5 of the transforming growth factor pi ( tgf - p ! ) gene are absent or too rare in chinese. compared the polymorphisms of these five markers with other populations using % 2 test and fisher ' s exact two - tailed test, significant differences of allele and genotype frequency distributions were observed at these polymorphisms ( p < 0. 001 )
結果表明： 1 ）白介素6 （ il ? 6 ）基因的? 174g c多態性、型膠原蛋白_ 1 （ col1a1 ）基因的sp1和rsa多態性、轉化生長因子_ （ tgf - _ 1 ）基因的內含子5t c多態性和糖皮質激素受體（ gr ）基因的asn363ser的多態性在中國人群中均未發現或者多態性很低； x ~ 2檢測和fisher精確（雙尾）檢驗比較這些多態性的頻率，發現在中國人群與其它種群或人群中，等位基因和基因型存在顯著的差異（ p 0 . 001 ） 。
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