signal transduction mechanism 中文意思是什麼

signal transduction mechanism 解釋
細胞信號轉導機制
  • signal : n 1 信號，暗號；信號器。2 動機，導火線 （for）。3 預兆，徵象。adj 1 暗號的，作信號用的。2 顯著的...
  • transduction : n. 1. 【物理學】能量轉換。2. 【生物學】轉導（作用）。
  • mechanism : n 1 （機械）結構；機械裝置[作用]；（故事的）結構。2 【哲學】機械論 （opp vitalism）。 3 【文藝】...
  1. According to the research of physiological and biochemical indicators or index, components of soluble proteins, substrate protein of phosphorylation and the activity of protein kinase in low - temperature stress in the leaves of brassica oleracea l., we tried to find the law of the physiological and biochemical response of brassica oleracea l. leaf to low temperature. at the same time, discussion on the signal transduction can also provide further evidences for revealing the mechanism of low - temperature stress. the results are showed as follows : malondialdehyde ( mda ), superoxide dismutase ( sod ), ascorbate peroxidase ( asp ) and peroxidase ( pod ) activities were changed greatly after 0 ~ 30min ' s treating with low temperature

    本文以甘藍葉片為材料，通過對低溫5脅迫下甘藍生理生化指標、可溶性蛋白組分以及磷酸化底物蛋白、蛋白激酶活性的研究，以期找出甘藍葉片對低溫脅迫的生理生化響應規律，為甘藍露地越冬栽培防範寒害提供理論指導，同時對低溫脅迫下甘藍逆境信號傳導進行了探討，從而為徹底弄清低溫脅迫機理提供進一步的證據，研究的主要結果如下：丙二醛含量（ mda ） 、超氧化物歧化酶（ sod ） 、抗壞血酸過氧化物酶（ asp ）和過氧化物酶（ pod ）活性在低溫處理0 30min發生顯著變化，低溫處理3min后，甘藍葉片內mda含量基本沒有變化，處理5min時出現第一個峰值，達到對照的104 . 10 ， 10min出現低谷，僅為對照的86 . 27 ，隨后再次上升， 30min時超過第一峰值，為對照的113 . 93 。
  2. The degradation of i k b and dissociation from nf - k b complex are essential process for activation of nf - k b. there is no report about whether cck - 8 inhibits nf - k b activity through inhibiting lps - induced degradation of i k b. the present study was designed to observe the regulatory effect of cck - 8 on changes of immune functions induced by lps, the receptor mechanism and signal transduction mechanism involving mapk, stat3 and i k b at different levels including in vivo and in vitro, in order to study its immunomodulatory effect on reversing es and its molecular mechanisms

    Ikb的降解、並從w兒b復合物上解離是w4b激活的必需過程。 ccks是否通過抑制lps誘導的ikb降解，從而抑制nf幾b激活尚未見報道。本研究在整體、細胞及分子水平，觀察了ccke對lps引起的免疫功能改變的調節作用，研究了其受體機制及mapk 、 stat3和ikb的信號轉導機制，以探討cck七抗es時的免疫調節作用及其分子機制。
  3. 12 yamada s, shiono s, joo a, yoshimura a. control mechanism of jak stat signal transduction pathway. febs lett., 2003, 534 : 190 - 196

    另外我們還模擬了單個信號蛋白的初始濃度的變化對系統輸出的影響，從而可以看出一些關鍵蛋白組分對系統變化的貢獻。
  4. Signal transduction mechanism of plant heat shock response

    植物熱激反應的信號轉導機理
  5. Abstract : in recent years, great progress has been made in the research field of plant hormone ethylene. this review focuses on the advances in the molecular biological research areas of ethylene biosynthesis pathway, ethylene signal transduction pathway and the mechanism of ethylene responese

    文摘:本文對植物激素乙烯的生物合成、乙烯傳號信導途徑、乙烯反應作用機制等方面的分子生物學進行了評述。
  6. The mechanism and significance of cellular signal transduction in kidney glomerular mesangial cells of rat with obstructive jaundice

    阻塞性黃疸腎臟系膜細胞內信號傳導的機制及其意義
  7. So the related mechanism studies of the cellular signal transduction have advantages for investigating biological effects of ele - emf

    對極低頻電磁場信號轉導過程的研究，有利於揭示其生物效應的機制。
  8. A series of 5 experiments were conducted to investigate the extraction, structure, immunomodulating effects of three chinese traditional herbal polysaccharides and approach the mechanism from view of cellular signal transduction

    本研究通過5個試驗研究了三種植物多糖牛膝多糖、蘆薈多糖和黃芪多糖的提取、化學結構及其對肉雞免疫功能的影響並從細胞信息傳導角度探討其作用機制。
  9. Signal transduction mechanism of inhibition of elemene on proliferation induced by recombinant human epidermal growth factor in lens epithelial cell

    欖香烯抑製表皮生長因子誘導的晶狀體上皮細胞增殖的信號轉導機制
  10. In the presented study, using h7721 human hepatocarcinoma cell line transfected with sense or antisense cdna of gnt - v, the effects of gnt - v on signal transduction an d its mechanism as well as the alteration of gene expression were investigated. we expected to elucidate whether and how the transfected glycosyltransferase modulate the cell signal transduction and gene expression

    本文以穩定轉染gnt - v正義或反義cdna質粒的h7721人肝癌細胞為材料，從下列四個方面對gnt - v影響信號轉導及其機制以及引起基因表達的變化進行了研究，企圖闡明糖基轉移酶轉染是怎樣調節細胞信號轉導的
  11. To study the biologic effects and the underlying mechanism of secretory phospholipase a 2 ( spla 2 ) and ceramide, we firstly investigated the relationship between certain lipid signalingmolecules - mediated signal transduction and the spla - induced cell death

    為了研究分泌型磷脂酶a2和神經酰胺對細胞產生的生物學效應及其機制，我們首先探討了某些脂類活性分子介導的信號傳導與分泌型磷脂酶a誘導的細2胞死亡之間的關系。
  12. Our previous work verified that heterotrimeric g protein was involved in regulation of pollen germination, tube growth and in the transmembrane mechanism of extracellular cam signal. in the present study, we provide further evidence that plc signaling pathway was presented in lily pollen and involved in extracellular cam signal transduction mechanism in pollen by molecular, biochemical and physiological approaches. these evidence included : the pip _ ( 2 ) - dependent plc activity was also detected in purified lily pollen protoplasts

    為了給上述信號轉導過程提供進一步的證據，本文以百合花粉為材料，從plc活性的測定、 plc基因的克隆及其與花粉萌發的關系、以及plc活性被g蛋白和cam調控等方面，為肌醇磷脂系統參與花粉萌發和細胞外鈣調素的信號轉導過程進一步提供了分子生物學和生物化學的證據。
  13. Abstract : plant responses to salt stress via a complex mechanism, including sensing and transducing the stress signal, activating the transcription factors and the corresponding metabolizing genes. since the whole mechanism is still unclear, this review emphasize the biochemical events during the plant adaptation to salt stress referring to an index of importance : the homeostasis in cytoplasm, the biosynthesis of osmolytes and the transport of water. most of these biochemical events were elucidated by study of halophyte and salt - sensitive mutations, also many important genes involved were cloned and used to generate stress - tolerance phenotypes in transgenic plants. on the other hand, about the molecular mechanism in signal transduction, the research of arabidopsis mutations and yeast functional complementation provided helpful traces but not full pathway

    摘要植物對鹽脅迫的耐受反應是個復雜的過程，在分子水平上它包括對外界鹽信號的感應和傳遞，特異轉錄因子的激活和下游控制生理生化應答的效應基因的表達.在生化應答中，本文著重討論負責維持和重建離子平衡的膜轉運蛋白、滲調劑的生物合成和功能及水分控制.這些生理生化應答最終使得液泡中離子濃度升高和滲調劑在胞質中積累.近年來，通過對各種鹽生植物或鹽敏感突變株的研究，闡明了許多鹽應答的離子轉運途徑、水通道和物種特異的滲調劑代謝途徑，克隆了其相關基因並能在轉基因淡水植物中產生耐鹽表型;另一方面，在擬南芥突變體及利用酵母鹽敏感突變株功能互補篩選得到一些編碼信號傳遞蛋白的基因，這些都有助於闡明植物鹽脅迫應答的分子機制。
  14. There are still many questions remain unanswered, including the mechanisms that specify oligochitosan recognition, the participation of additional molecules in transmembrane signaling, and the repertoire of downstream pathways activated by oligochitosan. it was also observed that pdtc did not totally block no production, which gave us another evidence that there must be some other signal transduction pathways ( perhaps mapk, pkc, ca2 + dependent signaling ) involved in the activation, so further investigation is necessary to clarify molecular mechanism of oligochitosan inducing immunological en

    Westemblot結果顯示100林歲ml劑量的殼寡糖作用於raw264 . 7細胞（ 4x105個細胞/ ml ） 4h ，胞核內p65的含量明顯增加， 6h時達到高峰， 10h時恢復到基礎表達量，這就提示在殼寡糖對巨噬細胞的激活過程中nf一kb活化狀態可以持續6個小時。
  15. In addition, the well retained stability and integrity of cell membrane of boea leaves might also be an important mechanism which make them resurrect well. by using mrna differential display, 5 desiccation sensitive cdnas, 52 desiccation - induced cdnas, 21 up - regulated cdnas, 14 down - regulated cdnas and 16 phosphate induced cdnas were obtained. the cloning, sequencing, homological blasting and northern blotting results of 5 desiccation - induced cdnas and 3 phosphate induced cdnas implied that signal transduction induced by desiccation, regulatory gene cascades and functional genes such as g protein, protein kinase, vp3 - and mad3 - like genes might be involved in dehydration in the resurrection plant boea hygrometrica

    對其中5個脫水特異誘導表達牛耳草光合作廠j的脫水保護和復甦機理的cdna （包括可能與復甦能力有關的cdna ）和3個磷酸鹽處理誘導表達的cdna進行克險測序、同源性探測和northern雜交檢測表明，牛耳草脫水過程中誘導表達的基因可能涉及到脫水脅迫的信號轉導「蛋白、蛋白激酶等） 、調節基因的級聯作用（ vp3 ， mad3樣基因等） 、結構基因產物調節細胞結構（包括細胞質膜）在脫水脅迫中的穩定性等。
  16. Despite intensive investgation on the detection. localization, biological roles and signal transduction pathway of extracellular cam in plants, the mechanism by which extrallular cam is activated by ca2 + has been unclear, manily because of specific of extrallular milieu

    已經證實，植物體普遍存在胞外鈣調素，它可能作為一種廣譜性多肽第一信使在細胞外產生多種生物學功能，並具有跨膜及胞內信號轉導機制。
  17. Phopholipase c - 1 ( plc - 1 ) is widely known to play an important role in regulating cell proliferation and differentiation, development of the organisms, cell transformation and oxidative stress. till now, the mechanism how phopholipase c - 1 acts can not be thoroughly illustrated, nor has the interaction between plc - 1 pathway and other signal pathways been systematically reported. this research chose 2 - de + ms as the basic method from all kinds of proteomics strategies and compared the total protein expression map of mef genetically deficient in plc - 1 ( plc - 1 - / - ) to that of wild type mef ( plc - l + / + ) aimed to find some protein spots differentially expressed, thus we can discuss the impact of knockout of plc - 1 on signal transduction initiated by growth factors such as egf comprehensively. in this way, we can study the biological function of plc - 1 and mechanism of plc - 1 pathway indirectly, which will contribute a lot to further analysis

    鑒于plc - 1發揮上述作用的機制尚未完全闡明， plc - 1通路與其他信號通路間的交聯和代償尚無系統報道，又因為以往的研究方法不夠全面，本研究以野生型小鼠胚胎成纖維細胞（ plc - 1 ~ （ + / + ） ）和缺失磷脂酶c - 1的小鼠胚胎成纖維細胞（ plc - 1 ~ （ - / - ） ）為研究模型，在眾多蛋白組學策略中選擇了雙向電泳+質譜（ 2 - de + ms ）作為研究手段，通過對比表皮生長因子（ egf ）刺激24小時後上述兩種細胞的總蛋白質表達差異，全面地探討敲除plc - 1對生長因子誘導的信號傳遞的影響，從而間接研究plc - 1生物學作用、信號傳遞機制及其代償情況，為后續的深入研究打下基礎。
  18. The following research areas will be involved in the project : ( 1 ) mechanism of hereditic factors and its function in chinese type 2 diabetes ; ( 2 ) metabolomics on the cell stress and its nutrition intervention in the type 2 diabetes ; ( 3 ) mechanisms of metabolic nuclear receptors in the process of insulin resistance and type 2 diabetes onset ; ( 4 ) roles of signal transduction molecules, lipid metabolic disorder to insulin resistance ; ( 5 ) type 2 diabetes development and role of pathological changes of blood vessels ; ( 6 ) abnormal insulin secretion, apoptosis and type 2 diabetes ; ( 7 ) function of molecular network of type 2 diabetes progression

    本項目擬開展以下研究工作： （ 1 ）中國人2型糖尿病發生過程中遺傳因素的發現及其作用機制； （ 2 ）細胞應激在中國人2型糖尿病發生過程中的作用機制及其營養干預的代謝組學； （ 3 ）代謝性核受體在胰島素抵抗和2型糖尿病發病中的作用機制； （ 4 ）細胞信號轉導分子、脂代謝紊亂與胰島素抵抗的關系； （ 5 ） 2型糖尿病發展過程與血管病變； （ 6 ）胰島素分泌異常、細胞凋亡與2型糖尿病； （ 7 ） 2型糖尿病發生過程中的分子網路與作用機制。
  19. His research interests are involved in the mechanism of pain and acupuncture analgesia, signal transduction and the study of neurodegenerative diseases

    和北京市自然科學基金委重點項目等有關「帕金森病的發病機制和防治基礎」研究的負責人，現任
  20. The cyclic gmp system represents the principal signal transduction mechanism by which no elicits many of its physiological effects in the mammalian species

    一氧化氮影響著哺乳類動物中的眾多生理作用，而環鳥?磷酸系統便擔當這些過程中的主要訊號轉導機制。
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