signal transduction of the cell 中文意思是什麼

signal transduction of the cell 解釋
細胞的信號轉導
  • signal : n 1 信號，暗號；信號器。2 動機，導火線 （for）。3 預兆，徵象。adj 1 暗號的，作信號用的。2 顯著的...
  • transduction : n. 1. 【物理學】能量轉換。2. 【生物學】轉導（作用）。
  • of : OF ＝Old French 古法語。
  • the : 〈代表用法〉…那樣的東西，…那種東西。1 〈用單數普通名詞代表它的一類時（所謂代表的單數）〉 （a） 〈...
  • cell : n 1 小室，單室；隔間，艙；〈詩〉茅舍；（單個的）蜂窩，蜂房。2 〈詩〉墓穴，墓。3 （大修道院附屬的...
  1. Our previous studies showed existence of apoplast cam in the plant cell and cam had many extracellular functions. so it supposed cam may be one of important extracellular polypeptides and trigger the intracellular signal transduction by binding the receptor. in this study, radiolabelled ligand is used to investigate the binding characteristic of cam and a. thaliana protoplasts. and chemical crosslinking is employed to explore binding proteins in the membrane. at first, ( 35 ) ~ s - cam was produced using ( 35 ) ~ s - labeled amino acid mixture in e. coli. sds - page and autoradiograph indicated high - purified, high - specific radioactivity ( 35 ) ~ s - cam was obtained. electrophoresis of ( 35 ) ~ s - cam is the same as that of unlabeled cam with ca ~ ( 2 + ) or egta ; a quatitive of protoplasts was prepared by enzymolysis

    首先，用~ （ 35 ） s標記的氨基酸混合物喂養工程菌成功地制備了~ （ 35 ） s標記的擬南芥鈣調素（ ~ （ 35 ） s - cam ） ， ~ （ 35 ） s - cam純度高、放射活度高、 ca ~ （ 2 + ）與egta存在時的電泳行為與未標記cam相同，可作為一種高靈敏性的探針用於進行受體學分析實驗；用擬南芥種子誘導愈傷，通過酶解制備了大量原生質體。
  2. Protein kinase a is camp - dependent kinase, one of the most important signal transduction pathways, plays a pivotal role in growth, differentiation, tumor occur, cell cycle control, etc. pka activators such as camp, 8 - br - camp or phosphodiesterase ( pde ) inhibitor isomethyl butyl xanthine ( imbx ) or purified pka catalytic subunit all can inhibit germinal vesicle breakdown ( gvbd ) and meiotic maturation in mouse oocytes, also in xenopus oocytes

    蛋白激酶a （ proteinkinasea ， pka ）是依賴于camp的絲蘇氨酸蛋白激酶，是重要的信號傳導途徑之一，廣泛參與許多生命過程，包括生長、分化、腫瘤發生、細胞凋亡、細胞周期調控等。以小鼠卵母細胞為實驗對象，給予pka激動劑camp 、 8 - br - camp或磷酸二酯酶抑制劑imbx （ isomethylbutylxanthine ）均可抑制小鼠卵母細胞的胚泡破裂及減數分裂成熟。
  3. Jak2 is one of the janus kinase family. it participates in the jak - stat signal transduction and plays roles in signal transduction of many cytokins and growth factors such as growth hormone, il and gm - csf. it plays essential roles in cellular functions, i. e. cell proliferation and differentiation

    Jak2是janus激酶家族中的一員，參與jak - stat信號通路，介導諸如生長激素、白細胞介素、 gm - csf等細胞因子和生長因子的信號傳導，在細胞的增殖、分化等活動中起重要作用。
  4. Curcumin has been shown to induce a wide variety of tumor cells by several mechanisms, mainly including modulation of the expression of oncogenes and cancer suppressor genes, down - regulation the activation of transcription factors, via many signal transduction pathways, and the modulation of cell cycle. provides an overview of domestic and international apoptosis mechanisms of malign tumor cells induced by curcumin in order to better explore and open up new avenues of cancer treatment

    姜黃素能夠誘導多種腫瘤細胞系凋亡，其機制主要是調控癌基因和抑癌基因，下調多個轉錄因子活性，通過多種信號轉導途徑，誘發細胞周期停滯而誘導細胞凋亡.對近年來姜黃素誘導細胞凋亡的機制進行綜述，以便更好地探求和開辟治療惡性腫瘤的新途徑。
  5. In the presented study, using h7721 human hepatocarcinoma cell line transfected with sense or antisense cdna of gnt - v, the effects of gnt - v on signal transduction an d its mechanism as well as the alteration of gene expression were investigated. we expected to elucidate whether and how the transfected glycosyltransferase modulate the cell signal transduction and gene expression

    本文以穩定轉染gnt - v正義或反義cdna質粒的h7721人肝癌細胞為材料，從下列四個方面對gnt - v影響信號轉導及其機制以及引起基因表達的變化進行了研究，企圖闡明糖基轉移酶轉染是怎樣調節細胞信號轉導的
  6. To study the biologic effects and the underlying mechanism of secretory phospholipase a 2 ( spla 2 ) and ceramide, we firstly investigated the relationship between certain lipid signalingmolecules - mediated signal transduction and the spla - induced cell death

    為了研究分泌型磷脂酶a2和神經酰胺對細胞產生的生物學效應及其機制，我們首先探討了某些脂類活性分子介導的信號傳導與分泌型磷脂酶a誘導的細2胞死亡之間的關系。
  7. In addition, the well retained stability and integrity of cell membrane of boea leaves might also be an important mechanism which make them resurrect well. by using mrna differential display, 5 desiccation sensitive cdnas, 52 desiccation - induced cdnas, 21 up - regulated cdnas, 14 down - regulated cdnas and 16 phosphate induced cdnas were obtained. the cloning, sequencing, homological blasting and northern blotting results of 5 desiccation - induced cdnas and 3 phosphate induced cdnas implied that signal transduction induced by desiccation, regulatory gene cascades and functional genes such as g protein, protein kinase, vp3 - and mad3 - like genes might be involved in dehydration in the resurrection plant boea hygrometrica

    對其中5個脫水特異誘導表達牛耳草光合作廠j的脫水保護和復甦機理的cdna （包括可能與復甦能力有關的cdna ）和3個磷酸鹽處理誘導表達的cdna進行克險測序、同源性探測和northern雜交檢測表明，牛耳草脫水過程中誘導表達的基因可能涉及到脫水脅迫的信號轉導「蛋白、蛋白激酶等） 、調節基因的級聯作用（ vp3 ， mad3樣基因等） 、結構基因產物調節細胞結構（包括細胞質膜）在脫水脅迫中的穩定性等。
  8. In brief, our courses will explore life phenomena at various angles including ( 1 ) global interactions of different biological communities ; ( 2 ) whole organism structures, development, physiology and functions ; ( 3 ) individual cell, cellular components and functions, and the signal transduction therein ; and ( 4 ) biochemical, genetic, and molecular basis of life

    簡而言之，本系的學科嘗試從不同的角度去了解生命現象，包括（ 1 ）生物社群間的宏觀相互作用; （ 2 ）生物個體結構、發育、生理及功能； （ 3 ）個別細胞，細胞成份與其功能，以及其間的訊號傳導; （ 4 ）生命的生化、遺傳和分子基礎。
  9. Effective activation of antigen - specific t cells not only requires the first signal transduction through t - cell receptor ( tcr ) binding with peptide - mhc complex on the antigen presenting cell ( apc ), but also needs the second signal, termed costimulation. costimulation critical to the degree and consequence of t cell activation is provided by interaction between soluble factors or cell - surface molecules on the t cell and on the apc

    而t細胞的活化除需要t細胞受體（ tcr ）與抗原呈遞細胞（ antigenpresentingcell ， apc ）表面的抗原肽- mhc復合物結合所形成的第一信號外，還需要t細胞和apc表面的其它膜分子結合所提供的共刺激信號（亦稱第二信號或輔助刺激信號， costimulatorysignal ）的參與。
  10. Objective to investigate the change of signal transduction genes in human transitional cell carcinoma ( tcc )

    摘要目的探討人膀胱移行細胞癌信號轉導相關基因的表達變化。
  11. The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation, such as zinc finger 198, 263, 14, 224, zf6, novel protein similar to transcriptional represser ctcf, and kruppel - like zinc finger protein ; two members of the adams ( a disintegrin and metalloprotease domain ) family ; two members of integrin family ; several proteins involved in the signal transduction, cell - cycle control, chromatin remodeling and transcription repression ; and also some proteins of cell skeleton and some with unknown functions

    鑒定出的蛋白包括多個與轉錄調控相關的鋅指蛋白，如鋅指蛋白198 、 263 、 14 、 224 、 zf6 、轉錄抑制因子ctcf樣蛋白、幻肚pple樣鋅指蛋白等:兩個含金屬蛋白酶結構域和整合素結合結構域的家族成員adam28和adam17 ;兩個整合素家族成員pz整合素和含十個egf樣結構域的整合素（ tied ） ;與細胞信號轉導通路有關的蛋白;與細胞周期調控有關的蛋白;與染色體重塑和基因轉錄抑制有關的蛋白;細胞骨架蛋白以及其他功能未明的蛋白等。
  12. Phopholipase c - 1 ( plc - 1 ) is widely known to play an important role in regulating cell proliferation and differentiation, development of the organisms, cell transformation and oxidative stress. till now, the mechanism how phopholipase c - 1 acts can not be thoroughly illustrated, nor has the interaction between plc - 1 pathway and other signal pathways been systematically reported. this research chose 2 - de + ms as the basic method from all kinds of proteomics strategies and compared the total protein expression map of mef genetically deficient in plc - 1 ( plc - 1 - / - ) to that of wild type mef ( plc - l + / + ) aimed to find some protein spots differentially expressed, thus we can discuss the impact of knockout of plc - 1 on signal transduction initiated by growth factors such as egf comprehensively. in this way, we can study the biological function of plc - 1 and mechanism of plc - 1 pathway indirectly, which will contribute a lot to further analysis

    鑒于plc - 1發揮上述作用的機制尚未完全闡明， plc - 1通路與其他信號通路間的交聯和代償尚無系統報道，又因為以往的研究方法不夠全面，本研究以野生型小鼠胚胎成纖維細胞（ plc - 1 ~ （ + / + ） ）和缺失磷脂酶c - 1的小鼠胚胎成纖維細胞（ plc - 1 ~ （ - / - ） ）為研究模型，在眾多蛋白組學策略中選擇了雙向電泳+質譜（ 2 - de + ms ）作為研究手段，通過對比表皮生長因子（ egf ）刺激24小時後上述兩種細胞的總蛋白質表達差異，全面地探討敲除plc - 1對生長因子誘導的信號傳遞的影響，從而間接研究plc - 1生物學作用、信號傳遞機制及其代償情況，為后續的深入研究打下基礎。
  13. The following research areas will be involved in the project : ( 1 ) mechanism of hereditic factors and its function in chinese type 2 diabetes ; ( 2 ) metabolomics on the cell stress and its nutrition intervention in the type 2 diabetes ; ( 3 ) mechanisms of metabolic nuclear receptors in the process of insulin resistance and type 2 diabetes onset ; ( 4 ) roles of signal transduction molecules, lipid metabolic disorder to insulin resistance ; ( 5 ) type 2 diabetes development and role of pathological changes of blood vessels ; ( 6 ) abnormal insulin secretion, apoptosis and type 2 diabetes ; ( 7 ) function of molecular network of type 2 diabetes progression

    本項目擬開展以下研究工作： （ 1 ）中國人2型糖尿病發生過程中遺傳因素的發現及其作用機制； （ 2 ）細胞應激在中國人2型糖尿病發生過程中的作用機制及其營養干預的代謝組學； （ 3 ）代謝性核受體在胰島素抵抗和2型糖尿病發病中的作用機制； （ 4 ）細胞信號轉導分子、脂代謝紊亂與胰島素抵抗的關系； （ 5 ） 2型糖尿病發展過程與血管病變； （ 6 ）胰島素分泌異常、細胞凋亡與2型糖尿病； （ 7 ） 2型糖尿病發生過程中的分子網路與作用機制。
  14. The experiment purpose is to confirm that there exist il - 2rand er in c6 glioma cell line whether at protein level or mrna level, and explore the effects of il - 2 and estradiol on the cells as well as the possible mechnism of signal transduction of them

    本次研究擬從基因與蛋白水平系統的證實c6大鼠神經膠質細胞有il zr與er表達，並分別初步探討ilz與雌激素對該細胞基本生理活動的影響，及其可能的信號轉導途徑。
  15. In conclusion, exposure of healthy subjects to traffic - related air pollution resulted in a lower airway inflammatory response with cell migration, together with signs of an initiated signal transduction in the bronchial epithelium

    總之，讓健康個體暴露于車輛廢氣中會降低有細胞遷移的氣道炎癥反應，同時也有跡象顯示啟動了支氣管上皮的信號傳導。
  16. Among sequenced 16 positive clones randomly selected, two represent novel expression tag sequences, two are homologous to two unknown proteins in genbank ; the rest are homologous to known or putative proteins or enzymes with definite functions by searching the genbank through blast program, which are involved in various life activities of cell such as regulation of gene expression, plant secondary metabolism, signal transduction, adversity resistance, stress response and defense reaction. significant changes of quantities of these gene fragments were observed before and after ssh, which indicated they were enriched after ssh

    隨機挑選了16個差異表達的克隆進行序列測定，經與genbank數據庫相關數據比較分析，發現有2個新的cdna片段（ ets ） ，有12序列與genbank中已知蛋白或推測蛋白質（ putativeprotein ）序列有高低不同的同源性，它們參與基因的表達調控、植物的次生代謝、信號傳導、抗逆、應激及防禦反應等細胞生命活動過程。
  17. Many cell signal transduction pathways have been discovered in the regulation of apoptotic induction and reduction. mito - gen - activated protein kinase ( mapk ) is a group of particular ser / thr protein kinases which are activated when its conservative thr and tyr residues are both phosphorylated by upstream mapk kinases

    絲裂原活化蛋白激酶（ mapk ）是一群特殊的絲蘇氨酸蛋白激酶，它通過其上游mapkk使其保守的蘇氨酸和酪氨酸殘基雙磷酸化而活化，活化的mapk可轉移到核內，參與基因表達調控。
  18. The effect of sh2a gene in cell signal transduction : sh2a is a novel member of sh2 signaling protein family

    討論一3h基因對細胞信號轉導的影響sh基因是sh 。信號蛋白家族成員之一。
  19. It is possible that they may modify the existing signal transduction procession in cell membrane, thus producing both transduction and biochemical amplification of the effects of the field itself

    因此一般認為電磁場可能通過作用於細胞膜上業已存在的信號轉導途徑，將物理信號轉化成生物信號，進而經過信號轉導及生物級聯放大，最終產生生物效應。
  20. The cell signal transduction of cervical intervertebral disc of rat and the regulating effects of yiqihuayu fang

    椎間盤細胞信號傳導及益氣化瘀方調控機理的研究
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