transcription regulation 中文意思是什麼

transcription regulation 解釋
轉錄調節
  • transcription : n 謄寫，抄寫；轉錄；抄本，繕本，副本；轉寫，翻譯；【音樂】樂曲改作；【無線電】錄音；錄音廣播；（...
  • regulation : n 1 規則，規程，規章，條例。2 控制，管理，限制，（情慾等的）節制。3 調整，調節，整頓。4 校準；穩...
  1. The insulin - like growth factor - 2 ( igf - 2 ) and igf conjugated protein - 6 ( igfbp - 6 ) mrna level in rat calvaria bone tissue and mc - 3t3 - el cells were detected by northern blotting analyses and reverse transcription polymerase chain reaction. the estrogen responsive element ( ere ) in igfbp - 6 gene promoter was identified and involved in tcdd - reduced regulation of the gene expression by electromobility shift assays ( emsa )

    正常胎鼠頭蓋骨組織igf一2mrna呈高水平表達狀態，而igfbp一6mrna的水平較低; ccf胎鼠頭蓋骨骨組織內igf一2mrna的表達較正常胎鼠降低， igfbp一6mrna的表達則明顯升高; atra和e :聯合應用時， atra可以抑制雌激素對細胞內igf一2和igfbp一6的這種調節作用。
  2. The tumor cells transfected with restin are arrested in gl phase and the cell proliferation is inhibited. it implies that restin may be correlated to cell cycle regulation. other data showed that the necdin, a homolog of restin, could suppress cell growth by interacting with transcription factor e2f1 and p53

    而與restin的同源蛋白的necdin ，可以與細胞周期促進蛋白sv40大t抗原、腺病毒eia 、轉錄因子ezfi等相互作用，抑制細胞生長;也可以和轉錄因子p53作用參與生長抑制和抑制p53誘導的細胞凋亡。
  3. Promotor, in broad sense, consists of transcription start site, binding site of rna polymerase ( promoter in narrow sense ) and upstream regulation sequence

    廣義的啟動子（ promotor ）包含有轉錄起始部位、 rna聚合酶與dna結合部位（也就是狹義的啟動子）以及上游調控序列。
  4. Curcumin has been shown to induce a wide variety of tumor cells by several mechanisms, mainly including modulation of the expression of oncogenes and cancer suppressor genes, down - regulation the activation of transcription factors, via many signal transduction pathways, and the modulation of cell cycle. provides an overview of domestic and international apoptosis mechanisms of malign tumor cells induced by curcumin in order to better explore and open up new avenues of cancer treatment

    姜黃素能夠誘導多種腫瘤細胞系凋亡，其機制主要是調控癌基因和抑癌基因，下調多個轉錄因子活性，通過多種信號轉導途徑，誘發細胞周期停滯而誘導細胞凋亡.對近年來姜黃素誘導細胞凋亡的機制進行綜述，以便更好地探求和開辟治療惡性腫瘤的新途徑。
  5. In summary, we constructed and characterized a bac library of silky, a unique chinese native breed of chicken. the library has high genome coverage ( 13 - fold ), chimerism ( 6 % ) and overlapped bacs, which made it a valuable resource to complete chicken physical map, study functional genes and construct bac contigs. we analyzed the whole genomic sequence and snps of tyrp1 and found that silky tyrp1 is different with other breeds both in microsatellite and transcription regulation site

    中國農業人學博卜學位論文摘要本研究構建了中國特有雞種絲羽鳥骨雞基因組bac文庫並進行了文庫質量鑒定，它所具有的13倍高基因組覆蓋率、 6 %的嵌合率和部分重疊的克隆使其成為完善雞的基因組圖譜、研究基因功能和構建bac重疊群的優質資源。
  6. It is a good model for the study on the regulation of eukaryotic gene transcription. in eukaryotes, the acetylation of histones was discovered many years ago

    其基因表達包括基礎水平表達和誘導表達兩個層次，代表了一類轉錄調控方式，是研究真核基因轉錄調控的一個很好模型。
  7. Design : induced by administration of den solution, we got the rat liver cancers model to observe the regulation effects of invigorating spleen and regulating qi to genetic transcription, which is relevant to the transcription and signal transduction in genome of rats - liver - cancer tissues, controlled treatments about chemotherapy of medicine - ftorafurum, and the two tcm treatments including expelling toxin by cooling and promoting blood circulation to remove blood stasis

    方法：以den誘導大鼠肝癌形成為模型，以西藥喃氟啶化療、中醫清熱解毒、活血化瘀治法為對照治療，採用基因晶元技術，觀察健脾理氣法對大鼠肝癌組織基因組轉錄水平及信號轉導相關基因轉錄的調控作用。
  8. The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation, such as zinc finger 198, 263, 14, 224, zf6, novel protein similar to transcriptional represser ctcf, and kruppel - like zinc finger protein ; two members of the adams ( a disintegrin and metalloprotease domain ) family ; two members of integrin family ; several proteins involved in the signal transduction, cell - cycle control, chromatin remodeling and transcription repression ; and also some proteins of cell skeleton and some with unknown functions

    鑒定出的蛋白包括多個與轉錄調控相關的鋅指蛋白，如鋅指蛋白198 、 263 、 14 、 224 、 zf6 、轉錄抑制因子ctcf樣蛋白、幻肚pple樣鋅指蛋白等:兩個含金屬蛋白酶結構域和整合素結合結構域的家族成員adam28和adam17 ;兩個整合素家族成員pz整合素和含十個egf樣結構域的整合素（ tied ） ;與細胞信號轉導通路有關的蛋白;與細胞周期調控有關的蛋白;與染色體重塑和基因轉錄抑制有關的蛋白;細胞骨架蛋白以及其他功能未明的蛋白等。
  9. It was indicated that regulation of 20ahsd activity was not due to post - translational modification by either phosphorylation cycle or glycosylation, but rather at the transcription level of 20ahsd gene expression in previous research papers

    以往研究表明20 hsd活性的調節不是通過糖基化、磷酸化或去磷酸化等翻譯后修飾實現的，而是以轉錄水平的調節為主。
  10. The most efficient regulation of gene occurs at transcription level by regulating the interaction between transcription factors and upstream regulation sequence. thus, to investigate promoter of a target gene will be helpful to predicate the principle of molecule regulation, biological function of molecule and even involving pathogenesis of some diseases

    轉錄水平是調控蛋白質表達效率最高的環節，通過影響相應的轉錄因子與啟動子和上游調控序列的相互作用調控目的基因的表達，因此研究基因的啟動子對于了解基因的表達調控規律、闡明分子的結構和生物學功能乃至疾病的發生都有重要的意義。
  11. The aim of this study was to investigate the differential expression of mpges and cpges in mouse uterus during early pregnancy and its regulation under different conditions by in situ hybridization and immunohistochemistry. mpges expression in the preimplantation mouse embryos was also performed by reverse transcription pcr ( rt - pcr )

    本實驗首先利用原位雜交和免疫細胞化學的方法，檢測小鼠正常妊娠1 - 8天子宮中mpges和cpges的表達情況，並利用假孕、延遲著床和人工誘導蛻膜化等模型研究mpges和cpges的表達及其調節。
  12. Its well established pkb play an important role in cellular processes such as glucose metabolism, cell proliferation, apoptosis, and transcription and cell migration. there are recent indications that pkb could have a wide spread function in cell cycle regulation, but little is known about the effect of pkb on the regulation of mammalian cell cycle, especially the mouse fertilized eggs

    Pkb akt的氨基酸序列測定揭示了它的c末端1 - 147位是調節區，稱為ah結構域，其中1 - 106位是ph結構域，這個區域包含約100個氨基酸，是血小板中pkc底物同源序列，且在pkb akt ， rasgtp ， msos和- spectrin中均被發現。
  13. In order to get some functional clues from their structures, the upstream regulation region of ndrgl gene and second structure of ndrg2 protein are performed bioinformatics analysis ; we found that there are several binding sequences of some diffirent transcription factors, their functions include regulating tissue - specific gene expression, regulating expression of genes related to growth and early development of cells, besides this, regulating expression of genes under some stimulated conditions, and so on. predict in protein fold classification shows that ndrg2 belongs to alpha / beta hydrolase fold family, and there are high similarity between ndrg2 and epoxide hydrolase from bacteria, this suggests that ndrg2 protein may has enzymatic functions associated with resisting the oxidative stress, maintaining the balance of cell redox potential, involving in the metabolism process of xenobiotics or intracellular toxic molecules

    研究發現呷基因的調控區存在多種轉錄因子結合位點，功能主要涉及組織特異性表達調控，細胞生長發育相關基因的表達調控，刺激反應基因的表達調控等； ndrgz蛋白在結構上屬于a小水解酶類折疊，折疊分類預測表明ndrg2與其中的的細菌環氧化物水解酶的二級結構極為相似，提示ndrgz蛋白具有一定酶活性，可能參與細胞抗氧化應激反應，維持細， an ） armtbffiofbfochmilsyn ） mdafblechmrbfobo4第四軍醫大學碩士學位論文胞內氧還電勢平衡，參與內外源有毒物質的代謝等。
  14. In the recent decade, more and more attention has been paid to the roles of acetylation in transcription regulation

    尤其是近十多年來，乙酰化在真核生物基因表達調控中的作用日益受到人們的關注。
  15. Combined with the results of histone deactylase inhibitor, it is suggested that histone acetylation plays an important role in hsp gene transcription regulation

    結合以上去乙酞化酶抑制劑的實驗結果，我們認為組蛋白乙酞化修飾參與了熱休克基因的表達調控。
  16. The mechanisms of acetylation in transcription regulation are unclear, and the role of the acetylation in hsp gene transcription regulation is still a disputed issue

    一直以來，乙酰化是否參與熱休克基因表達調控以及乙酰化在基因調控中的作用機制都存在爭議。
  17. The study on the relationship between the acetylation and hsp gene transcription regulation will help us in understanding the mechanisms of eukaryotic transcription regulation

    因此，對乙酰化與熱休克蛋白基因表達調控關系的深入研究，將有助於我們對乙酰化參與的真核生物基因表達調控的理解。
  18. Promoter prediction is an essential task in the research of transcription regulation, but computational prediction of promoters has been one of the most elusive problems despite considerable effort devoted to the study

    摘要啟動子預測是研究基因轉錄調控的重要環節，但現有演算法的預測正確率偏低。
  19. In this thesis, we studied the effects of acetylation on hsp gene transcription regulation in drosophila melanogaster, in an attempt to disclose the mechanisms of the acetylation in hsp gene inducible transcription, at both the molecular and the chromosomal levels. the main results and conclusions are as followings

    本文以黑腹果蠅為實驗材料，從不同角度研究了乙酰化修飾與熱休克基因表達調控的關系，並對乙酰化修飾在熱休克基因的誘導表達中的作用機制進行了探討，建立了分子水平與染色體水平上的聯系。
  20. Aes contains a glutamine - rich ( q ) domain in its n - terminal, which sharing high homology with the amino terminal region of groucho / tle ( transducin like enhancer of split ). the function of aes is not clear yet, while groucho / tle were found to be a family of transcription co - repressor and play impo rtant roles in notch signaling, wnt - 0 catenin signaling and other transcription regulation events

    Aes的n -末端約130個氨基酸中富含谷氨酰眩（ q ）殘基，形成一個q結構域，與轉錄協同抑制分子tle （ transducinlikeenhancerofsplit ）的氨基端高度同源。
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