transforming growth factor (tgf) 中文意思是什麼

transforming growth factor (tgf) 解釋
轉化生長因子
  • transforming : 重排
  • growth : n. 1. 生長，成長，發育，發展。2. 栽培，培養。3. 生長物，產物；【醫學】瘤，贅生物。4. 【經濟學】（資本價值與收益的）預期增長。
  • factor : n 1 〈英國〉經銷人；（代客買賣收取傭金的）經紀人；代理商；代辦人；〈蘇格蘭語〉 土地經管人。2 要素...
  • tgf : 神降
  1. Pulmonary fibrosis was induced in the model group by intranasal instillation of bleomycin 5 mg kg. hxd were given via gastrogavage to the hxd prevention group and treatment group respectively at 48 h before and 14 days after they were modeled with the same method, and the groups of ligustrazin and prednisone, treatment and prevention, were managed the same as for hxd groups, but with ligustazin and prednisone instead of hxd respectively. bronchoalveolar lavage fluid balf and lung tissue of animals were gathered on day 28 cellular ultrastructural changes of lung was examined under electron microscope by he, masson stain ; content of hydroxyproline in lung tissue was assessed by acidolysis method ; and concentration of transforming growth factor 1 tgf 1 in balf was assessed by elisa

    方法68周雄性icr小鼠分8組，模型組bm組經鼻滴入博萊黴素blm 5 mg kg建立肺間質纖維化模型，化纖湯預防治療組pht組于滴入blm前48 h予化纖湯灌胃，化纖湯治療組ht組于滴入blm后第14天用化纖湯灌胃，同時設立丹參預防治療組pdst組及丹參治療組dst組，地塞米松預防治療組pdt組及地塞米松治療組dt組，並與正常小鼠nc組進行對照。
  2. Follistatin, a kind of secreted protein, is known to antagonise the function of several members of the tgf - beta ( transforming growth factor - beta ) superfamily including myostatin, the most powerful inhibitor of muscle growth characterised to date

    卵泡抑素（ follistatin ）是一種分泌蛋白，它可以拮抗tgf - beta （ transforminggrowthfactor ，轉化生長因子）超家族中幾種成員的功能，包括myostatin 。
  3. Transforming growth factor, tgf

    目的明確大腸癌細胞在轉化生長因子
  4. In order to further investigate the role of axudl in human tumor carcinogenesis and the potential association between the axudl gene expression status and the stimulation of transforming growth factor beta in human cancers, the present study was performed in three aspects as follows : ( 1 ) cloning full length enconding region cdna of axudl and construction of eukaryotic vector that expression the fusion protein of axud1 and influenza virus hemagglutin ha epitope tag ; ( 2 ) exploring the time and dose effects of tgf - 1 on the expression - of axudl gene in hepg2 hepatoma cells and spc - a1 lung carcinomas cells, and studying the effects of overexpression of axud1 on the expression of cell cycle and apoptosis related protein in hepg2 hepatoma cells ; ( 3 ) construction and expression of human axudl in e. coli m15. the following main results and conclusions can be obtained from the present study : 1. the full length ecnoding region of human axudl cdna from human peripheral blood lymphocytes was successfully cloned using one step rt - pcr method, and constructed into a eukaryotic expression vector which can be expressed a ha - axud1 fusion protein with axud1 and influenza virus hemagglutin ha epitope tag. the recombinant plasmid was identified by polymerase chain reaction, restriction endonuclease maping and sequencing, this expression vector might be instrumental to further study the function of axud1 protein in tumor cells

    為了進一步研究axud1在人類腫瘤發生中的作用及axud1基因的表達狀況與tgf -介導的信號通路的關系，本實驗研究分為三個部分： （ 1 ） axud1基因cdna全長編碼區的克隆和ha表位標記的axud1基因表達載體的構建； （ 2 ）探討肝癌細胞hepg2和肺腺癌spc - a1細胞中tgf - 1誘導的axud1基因表達的時間、劑量效應以及誘導表達的可能機理，並研究axud1的過表達對細胞周期和細胞凋亡相關蛋白表達的影響； （ 3 ） axud1原核表達載體的構建及其在大腸桿菌中的表達。本實驗的主要結果和結論如下： 1利用一步法rt - pcr成功地從人類外周血淋巴細胞中克隆出axud1基因編碼區cdna ，並將其構建入真核表達載體中，編碼的ha - axud1融合蛋白帶有流感病毒凝血素ha的表位標記肽段。
  5. Materials : in this study, bone marrow stromal cells ( bmscs ) were used as seed cells of chondrocyte tissue engineering after transfected transforming growth factor ( tgf ) - ft, gene by lipofectamine. then the biological characters of the transfected bmscs were investigated by many methods

    本研究以骨髓基質幹細胞（ bmscs ）作為靶細胞， tgf _ 1基因片段作為目的基因，經lipofectamine轉染目的基因與靶細胞中，觀察bmscs經基因轉染后的生物學特性。
  6. Our results showed as follows : 1 ) the spl and rsal polymorphisms of the collagen type 1 alpha 1 ( col1 al ) gene, the - 174g / c promoter polymorphism of the interleukin - 6 ( il - 6 ) gene, the asn363ser polymorphism of the glucocorticoid receptor ( gr ) gene, and the t ? c polymorphism in intron 5 of the transforming growth factor pi ( tgf - p ! ) gene are absent or too rare in chinese. compared the polymorphisms of these five markers with other populations using % 2 test and fisher ' s exact two - tailed test, significant differences of allele and genotype frequency distributions were observed at these polymorphisms ( p < 0. 001 )

    結果表明： 1 ）白介素6 （ il ? 6 ）基因的? 174g c多態性、型膠原蛋白_ 1 （ col1a1 ）基因的sp1和rsa多態性、轉化生長因子_ （ tgf - _ 1 ）基因的內含子5t c多態性和糖皮質激素受體（ gr ）基因的asn363ser的多態性在中國人群中均未發現或者多態性很低； x ~ 2檢測和fisher精確（雙尾）檢驗比較這些多態性的頻率，發現在中國人群與其它種群或人群中，等位基因和基因型存在顯著的差異（ p 0 . 001 ） 。
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