嵌合分子 的英文怎麼說
中文拼音 [qiàngěfēnzi]
嵌合分子
英文
chimeric molecule-
Based on the structure and function analysis of hirudin, a potent thrombin inhibitor, and some platelet aggregation inhibitors, which contain the recognition sequence argglyasp as their functional motif, two chimeric antithrombotic molecules were designed by introducing rgd sequence to hirudin cterminus. these chimera genes were constructed by pcr and inserted into the expression vector pet21a, the constructs were confirmed by restriction enzyme digestion and dna sequence analysis. these recombinant plasmids were transformed into
經限制酶消化和dna序列分析,證明兩種重組質粒與設計完全一致。由於rgd -水蛭素嵌合基因上游連接了金黃色葡萄球菌蛋白a spa的信號肽序列,在iptg誘導下兩種嵌合分子都獲得了分泌表達,表達產物主要集中在細胞周質空間。Strain bl21, and gene expression was induced by iptg. the target proteins were directed into the periplasmic space by the staphylococcal protein a signal sequence preceding the rgd - hirudin gene. using ion exchange chromatography and gel filtration chromatography, the chimera proteins were purified, and both of them showed a single band in tricine - sds - page. the results of activity analysis suggested that these two chimera proteins not only have antithrombin activities, but gain platelet aggregation inhibitory activities as well
通過離子交換層析和凝膠過濾層分別對兩種嵌合體蛋白進行純化,純化產物在tricine - sds - page中都顯示為單一條帶。活性分析結果表明兩種嵌合體蛋白在保留水蛭素抗凝血酶活力的同時,還呈現抗血小板聚集活性。After completing the mctf using db2 wavelet, it is well integrated with discrete wavelet transform ( dwt ) and embedded zero tree wavelet. it uses atom structure to organize the coded bit - stream to achieve the brilliant combination of three scalabilities : temporal, spatial and psnr scalabilities. and the software platform is based on vc + + 6. 0
在基於db2小波的運動補償時域濾波方法實現之後,本文將之和離散小波變換( dwt ) 、嵌入式零樹編碼進行有機結合,並採用基於基本原子粒的數據流組織結構將分層后的數據流有效地組織起來,實現了具有時間、空間、質量三方面的完整可伸縮性的編解碼系統,系統的軟體平臺基於vc + + 6 . 0實現。The enthalpy change on dsc curve suggests that the transition is one from low - ordered state to a higher - ordered state. a stacking mood that the 4 - trifluoro - methyl - 2, 3, 5, 6 - tetrafluorophenylmserts in between two perylene - macrocycles is confirmed by theoretical quantum calculation, such an insertion effect leads to the inversion of ( 0, 0 ) and ( 0, 1 ) absorption features under low temperature and the dramatic decrease of exciton coupling, which contributes to the spectral similarity in solution and the solid state
量子化學的計算結果支持氟取代的苯環嵌入兩個相鄰的?環之間的分子堆砌方式,使得在常溫到150左右f - ptcdi固體薄膜的紫外-可見吸收光譜的( 0 , 0 )和( 0 , 1 )性狀的強度對比發生「反轉」 ;氟取代苯環的嵌入大大降低激子耦合,使固體吸收光譜性狀與溶液類似。Different amount of copies in different tissues attribute to the different density of positive signals. the result of the experiment suggested that the transgenic animals can be produced by spermatozoa - mediated gene transfer after the entrapment of liposome. and because the exogenous dna occurs losing the segments. partly integration, or existin g outside of genome dna, the rate of chimerism is relatively high
結果表明: ( 1 )脂質體包裹外源基因轉染精子的方法,可將外源基因導入受精卵中,能夠獲得轉基因動物,並得到了較高的轉基因陽性率; ( 2 )精子攜帶的外源dna的整合過程是隨機的,在受精過程和胚胎早期分化過程中可能發生了片段丟失、不完全整合或游離于基因組存在而產生嵌合體。Layered and pillared material are a kind of multifunctional material which were developed in recent years, much attention has been paid to this kind of material for its application in ion - exchange catalysts solid state proton conductivity, nonlinear optics and physic. a lot of literature have reported the intercalation behavior of a - zirconium phosphate ( abbreviated as a - zrp ), different guest molecules inserted into a - zrp have been studied in detail, those guest molecules include amine, alcohok amino acid protein, enzyme coornadiate compound and coronal compound. the intercalation guest is restricted by their size and basicity
層柱材料是近年來發展起來的一類多功能材料,由於其在離子交換、催化、固態質子導體、非線性光學以及醫學等方面的廣泛應用而受到國內外研究者的重視,大量文獻報道了-磷酸氫鋯zr ( hpo _ 4 ) _ 2 ? h _ 2o ( - zirconiumphosphate ,縮寫為- zrp )的超分子插層化合物及插層性能,其中對不同的客體分子對磷酸鋯的嵌入做了詳細的報道,客體分子的種類包括氨、醇、氨基酸、蛋白質、酶、配合物、冠狀化合物等。The calculation of surface energy of metals al, cu and ni by using the molecular dynamics combining the eam potential, we calculated the surface energy of some high miller index surfaces belong to the ( 001 ) to ( 111 ) and ( 001 ) to ( 110 ) in al, cu and ni
金屬表面的表面能的計算基於半經驗嵌入原子勢( eam )的分子動力學方法,對al 、 cu 、 ni三種金屬位於[ 001 ]晶帶和[ - 110 ]晶帶的高密勒指數表面的表面能進行了分子動力學模擬計算,計算結果同已有的實驗結果相符合。The omt after its suspension treated with ultrasonic wave was inserted with poly ( styrene - butyl acrylate ) emulsion. xrd test found the layers of omt particles were dispersed partly in the composite ; extraction experiment of nano - omt / pba - st composite indicated a great amount of macromolecule has inserted into the interlayer of omt. dta analysis showed the decompose temperature of composite has improved by 73 at 4 % omt
將omt的水懸浮液經超聲波處理,與苯丙乳液復合, omt p ( ba - st )復合物的萃取和xrd試驗證明乳液的大分子已經大量嵌入omt層間,使大部分omt以納米級均勻分散於苯丙乳液之中; dta分析結果說明添加4 omt苯丙復合材料的分解溫度升高了73 。The group established r d center, with very powerful technical backup, mainly exploits and manufactures products of xinfa brand, including polyurethane sieve - plates pu sieve - plates, polyurethane roller pu roller, pu slice, pu bar, pu piece, pu elastic web gears and other polyurethane elastomer
鑫發聚氨酯篩板是使用高分子聚合材料聚氨酯,部分內嵌金屬骨架構成。聚氨酯是一種高分子聚合材料又稱「橡膠之王」 ,以前大部分篩板篩網是由不銹鋼金屬絲多孔板高彈線和傳統橡膠製成。Abstract : a new approach, gate - capacitance - shift ( gcs ) approach, is described for compact modeling. this approach is piecewise for various physical effects and comprises the gate - bias - dependent nature of corrections in the nanoscale regime. additionally, an approximate - analytical solution to the quantum mechanical ( qm ) effects in polysilicon ( poly ) - gates is obtained based on the density gradient model. it is then combined with the gcs approach to develop a compact model for these effects. the model results tally well with numerical simulation. both the model results and simulation results indicate that the qm effects in poly - gates of nanoscale mosfets are non - negligible and have an opposite influence on the device characteristics as the poly - depletion ( pd ) effects do
文摘:提出了一種新的建立集約模型的方法,即柵電容修正法.此方法考慮了新型效應對柵電壓的依賴關系,且可以對各種效應相對獨立地建模並分別嵌入模型中.另外,利用該方法和密度梯度模型建立了一個多晶區內量子效應的集約模型.該模型與數值模擬結果吻合.模型結果和模擬結果均表明,多晶區內的量子效應不可忽略,且它對器件特性的影響與多晶耗盡效應相反The thermodynamic and mechanical properties are calculated, it shows the melting point reduce in nizr alloy nano material. further we study the microstructure of them by the reverse monte carlo simulation, obtain the a series of information about bond angle - coordinate and so on
Dft結合實驗數據導出的嵌入原子勢用於納米nizr合金熱力學性質的分子動力學模擬,模擬結果證實了納米合金材料由於界面結構原子分佈比較混亂,與常規合金相比體系嫡較大,熔點降低,得到與實驗一致的結果。Objectives to improve the effect of a single mtb8. 4 dna vaccine, we constructed a chimeric mtb8. 4 / hil - 12 eukaryotic plasmid by linkage of mycobacterium tuberculosis mtb8. 4 gene to human il12 gene with a simple linker ( gly4 - ser ) 3. we analyzed the immunogenicity of chimeric dna vaccine and investigated the immune responses elicited when mtb8. 4 / hil12 was presented as endogenous ag
目的:以il - 12作為分子佐劑,與結核桿菌新抗原mtb8 . 4基因連接形成嵌合分子,將其克隆到真核表達質粒中,構建成嵌合dna疫苗,研究其在小鼠體內誘導細胞免疫應答的效果及對c57bl 6n小鼠的免疫保護作用,為尋求安全、有效、廉價的結核病新疫苗打下基礎。High resolution digital smps becomes the hotspot in the power supply field. more and more attention has beed payed to how to realize high resolution digital smps, and it has already taken a long step develop. improving the resolution of digital smps by new techniques becomes a forever topic. under the learning of the status and develping trend of smps, considering the practical requirement of task, a control system of smps implemented by microcontroller with high resolution, high speed, high integration is carried out. by combining the embedded system and power electronics, it is discussed that a high resolution smps ’ s output voltage with 0. 01 % resolution pwm wave output, in the basis of microcontroller, and the pwm wave double modulation arithmetic
不斷用新技術手段實現數字開關電源的高精度是一個永恆的話題。經過了解國內外開關電源的發展現狀和發展趨勢,結合實際課題的要求,提出了使用高精度、高速度、高集成度的微控制器組成開關電源的控制系統。討論了將嵌入式系統與電力電子結合,在微控制器硬體基礎上通過軟體pwm波雙調制演算法輸出高精度pwm波,實現開關電源輸出電壓的萬分之一精度的方法。The research respecting to ec based on xml data exchange is still in the initial phase in china. this dissertation aim to research and design an b2c e - commerce platform based on xml data exchange, mainly to solve how to imbed a xml document in a asp program, to produce xml documents involving different data sources by using asp dynamic situation, to screen the structure differences of every data sources and offer the customer a unified inquiry method and inquiry interface, and also solve how to real ize the separation of data content and display format using extensible stylesheet language ( xsl ), and finally to realize the personalized display
我們國家在基於xml數據交換的電子商務方面的研究還處于剛剛起步階段,因此本文就基於xml數據交換的b2c電子商務系統開發作了一些有益的研究,主要解決在結合xml與asp開發電子商務系統中,如何將xml文檔嵌入asp程序,利用asp動態生成包含多數據源的xml文檔,屏蔽各種數據源結構上差異,為用戶提供一個統一的查詢手段和查詢界面;如何利用xml的可擴展樣式語言xsl實現數據內容與顯示格式的分離,從而達到個性化顯示的目的。Medical instruments ; uterine scissors, straight, type sims without carbide inserts
醫療儀器.第1部分:無鑲嵌硬質合金的西姆斯氏直形子宮In the paper, li5mn4o83 + li5mn12o24 -, li5mn16o32 +, li17mn16o329 + clusters selected by " seed atoms " were calculated theoretically by means of the quantum chemical dv - xa calculation method. form the angle of electronic structure, the status of lithium ion and the electrochemical properties of lixmn2o4 were discussed preliminarily according to different conditions ( x = l, 2 ). based on calculation results, it ' s found that the jahn - teller distortion, which was thought to lead to poor cyclability, occurred during the discharge of lixmn204, and we also confirmed the formation of a novel phase with low energy after overdischarge ( x = 2 )
為了從微觀上認識錳系正極材料的結構和電化學性能之間的關系,本文提出了採用量子化學離散變分x (方法,對結合「種子原子法」選取的li5mn4o83 + 、 li5mn12o24 - 、 li5mn16o32 + 、 li17mn16o329 +等錳系正極材料的原子團簇進行了理論計算,從電子結構上初步探討了鋰離子嵌入正極材料后的存在形式以及鋰離子的嵌入對電極材料電化學性能的影響,同時還從結構上對鋰離子電池的循環性能和容量進行了初步的討論。Synthesis and mesophase characterization of block molecules with different topologies
不同拓撲構型嵌段液晶分子的合成與相變行為In order to prove hwtx - i that can be used as one of natural scaffolds for protein engineering. we have synthesized two multiple mutants : hw - ma and rgd - ma and natural co - conotoxin mviia by using solid phase method with fmoc chemistry on peptide synthesizer and by hand respectively
為了證明hwtx -可以作為蛋白質工程研究的一種天然的骨架分子,本文運用fmoc化學,用手工和固相合成儀合成了兩個hwtx -的多個位點的嵌合體: hw - ma及rgd - hw ,以及合成了天然- conotoxinmviia 。Based on the basic principles of polymer material and tribology the comprehensive investigation on the tribology behavior of polymer - matrix composite material has been made about solid lubricant used in the embedded bearing for hydraulic generator
本研究論文以摩擦學、高分子材料基本理論為指導,以水輪發電機鑲嵌軸承用固體潤滑劑為研究對象,進行高分子基復合材料的摩擦學行為的全面研究。Furthermore, by inserting " anther box " element to the mutated area of two site - mutation promoters, another two promoters, ipmas and ipmal, were created. in order to study the chemical - inducible capacity of wild and modified pr - la promoters, a coding sequence of gus ( | 3 - glucuronidase ) gene was fused to their downstre am, and the chimeric genes were cloned into pbin ! 9 - based plant expression vector
為了檢測得到的啟動子驅動效率及誘導活性,將所得到的啟動子、定點突變啟動子和插入花藥盒的啟動子與gus基因連接,構建了6個植物表達載體,同時分別構建包含ipl barnase 、 ipml barnase 、 ipmal barnase嵌合基因的植物表達載體。分享友人