We focused on the following aspects ; 1 ) we first assayed the expression of complement receptors and complement - associated molecules on distinct subsets of dendritic cells during their development in order to understand the physical basis of the sensitivity of dendritic cells to complement and its split products ; we next studied the effects of complement activation on the survival of dendritic cells during their development ; and finally examined the effects of the whole complement system, focusing on the ability of one of the split products of complement activation, c5a, and its first subcomponent - c1q, to influence chemotaxis of dendritic cells, as well as allo - t cell stimulatory activity of dc
我們通過免疫磁珠分離了兩種人dc前體,即髓系來源的單
核細胞( monocytes , mo )和淋巴系來源的
漿細胞樣dc ( plasmaeytoiddendriticeells , pdc ) ,對這兩個不同dc亞群進行體外誘導培養,使其處于不同的分化發育階段,然後檢測了其表達補體受體一cd35 ( cri ) 、 cd21 ( crz ) 、 cdilb ( cr3 ) 、 cdlle ( cr4 ) ,補體調控蛋白一cd46 、 cd55 、以及部分補體片斷分子受體一c3ar 、 csar 、 clqrp的水平。
Cytokinesis block micronucleus method
胞
漿阻滯微
核法
To investigate the consequence of this interaction, aes - rfp fusion protein expression vector was constructed and co - transfected into nih 3t3 cells with tle1 - gfp fusion protein expression vector. confocal microscopy observation showed that aes could interact with tle1 at the cytomembrane region. moreover, this interaction inhibited the concentration of tle1 into nucleus
在構建了紅色熒光蛋白aes表達載體后,將其與tle綠色熒尤蛋白載體共轉染細胞,共聚焦顯微鏡觀察發現這兩種分子在胞
漿中有共存現象,而且aes的表達可抑制tlei向胞
核內的聚積。
Changes in p - catenin expression or localization were found in cancer cells and tumor tissues, it had been reported that p - catenin translocated from membrane at the normal condition into the cytosol or nucleus in cancer cells. recently, p - catenin has been referred to an oncogene
研究發現,癌變的細胞中-連環蛋白的分佈發生了異常,由胞膜轉移到胞
漿和胞
核,因此,已把-連環蛋白歸為一個新的癌基因。
Translocation from endocytic compartments to the cytosol is the essential and rate - limiting step in the intoxication process of most toxins such as ricin, diphtheria toxin, shiga toxin and pseudomonas exotoxin ( pe ). a number of these toxins are transported to trans - golgi network ( tgn ), and in many cases such transport to the tgn is required for the translocation and cytotoxicity. in deed, 5 % of the ricin endocytosed by cells has been shown to reach the tgn
蓖麻毒素進入細胞的機理不甚明了,一般認為是rtb先與細胞膜受體結合,主要經過受體介導的內吞作用進入吞噬體,然後沿著內體、高爾基體、內質網等逆向分泌途徑,有序地運輸到內質網,最後從內質網轉位進入細胞
漿,在胞
漿內攻擊
核糖體,從而抑制蛋白質的合成,導致細胞死亡。
The dongming poplar floss slurry ltd., which major product is flakeboard, and chengwu senli manmade board ltd., which major product is moderate density fiberboard had became one of the ten major forest corporations. and we have brought up another 15 major forest corporations. now ten machining colony, such as tung spelling board of chao country zhuangzhai, strip willow basketry of pulianji, veneer of yuncheng huang ’ an, hub processing of juancheng shiji, furniture of zhangzhimen, decorating wood line of shanxian, hub processing of chengwu, veneer of xinxing and lizhuangji in peony borough, had formed in heze
至2003年底,全市獨立
核算的森工企業發展到2984多家,其中東明楊木絨毛
漿有限公司、定陶縣林盾木業有限公司(主要產品為刨花板) 、成武森利人造板公司(主要產品為中密度纖維板)步入了全省十大林業龍頭企業的行列,培植了十五大龍頭企業;全市形成了曹縣莊寨桐木拼板、普連集條柳編製品、鄆城黃安膠合板、鄄城什集木片加工、張志門傢具、單縣浮崗裝飾木線條,成武孫寺木片加工、牡丹區新興和李莊集膠合板等十大加工群體,林業產業化發展勢頭良好。
Abstract : large time delay exists in complicated practical processes. for example, in fccu ( fluidized catalytic cracker unit ) reactor - regenerator, the feed is preheated through heat exchanging from fractional column slurry, thus results in large time delay. a predictive control system is designed for such processes, where the kernal algorithm is dynamic matrix control. application results show that the control behavior is improved than original pid control
文摘:實際的復雜工業過程,往往具有大的時滯,例如:煉油廠催化裂化裝置的反應再生系統,其原料油預熱通過油
漿換熱實現,因此時滯特別大.本文針對這一類大的時滯過程,設計了以動態矩陣控制為
核心演算法的預測控制系統,運行實踐表明:這一控制方案比原pid控制在控制質量上有較大提高
The primary cell propagated 8 times and were small fusiform or triangle and smaller than hepatocytes with larger nucleus and less plasma ; it was 88. 2 % in the growing period of 4 ( superscript th ) generation cells and the stains of alb and ck19 were positive in immunocytochemical
所獲得的原代細胞共傳8代,細胞呈小梭形或三角形,體積較小,胞
核較大,而胞
漿較少;第4代細胞中進入生長期的細胞約佔88 . 2 % ;免疫細胞化學染色顯示細胞胞質中alb 、 ck19染色陽性。
Also the plasmutocyte is divided into trophic nucleus hematocyte and micronuclei hematocyte
其中
漿血胞可分為大
核漿血胞和小
核漿血胞兩種。
Through the study of the example of shaxi porphyry body in anhui province, the authors first figured out the storage time of plagioclase phenocrysts, then calculated the nucleation rate and growth rate of the crystals and, on such a basis, established the thermal model for cooling of the hypabyssal magmatic system
本文試圖通過對安徽沙溪斑巖體進行實例研究,先求出斜長石斑晶的存儲時間,再算得晶體成
核速率和生長速率,進而建立起淺成巖
漿體系冷卻的熱模型。
Having discussed the various special structural regions of the nucleus, there remains the nucleoplasm.
上面已討論了
核的各種特殊結構區域,但未提及
核漿。
Occasionally the cells may be small with high n : c ratios. the nuclei are irregular, enlarged and hyperchromatic
偶爾有小細胞,其核漿比例也大。細胞核增大、不規整、深染。