核輔助因子 的英文怎麼說
中文拼音 [héfǔzhùyīnzi]
核輔助因子
英文
nuclear accesory factor- 核 : 核構詞成分。
- 輔 : Ⅰ動詞(輔助) assist; complement; help Ⅱ形容詞(輔助) subsidiary Ⅲ名詞1 (車輪外旁增縛夾轂的兩條...
- 助 : 動詞(幫助; 協助) help; assist; aid; support
- 因 : Ⅰ動詞[書面語] (沿襲) follow; carry on Ⅱ介詞1 [書面語] (憑借; 根據) on the basis of; in accord...
- 子 : 子Ⅰ名詞1 (兒子) son 2 (人的通稱) person 3 (古代特指有學問的男人) ancient title of respect f...
- 輔助 : 1. (從旁幫助) assist 2. (非主要的) supplementary; auxiliary; subsidiary
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Fmn ( flavin mononucleotide ) a derivative of riboflavin that is a coenzyme in electron - transfer reactions
黃素單核苷酸( fmn ) :核黃素的衍生物,在電子傳遞反應中是一種輔酶,作為多種脫氫酶的輔助因子起作用。To target this mitochondrial enzyme into chloroplast, the cdna sequence of mnsod was fused to a chloroplast transit peptide from a pea rubisco small subunit gene, whereas expression of the chimeric gene was driven by the camv 35s promoter
Pchlsod質粒含有煙草mnsod基因的cdna序列,與豌豆核糖體小亞基葉綠體引物肽( tp )的編碼基因序列構成融合基因,由35s啟動子調控。 npt基因為選擇標記基因, pgv2260為輔助質粒。To search proteins that associate with the mouse mint protein and regulate notch signaling in nuclei, and to study the function and mechanism of mint - mediated transcription repression, yeast two - hybrid assay was used to screen proteins that interact with a fragment of mint ( f5, amino acids 2226 - 2959 ). from 4x106 yeast clones transformed with the bait plasmid and a cdna library of 9 dpc mouse embryo, fifty - one were positive for nutritional screening and p - galactosidase assay. restriction digestion identified 10 independent positive clones and these were analyzed by dna sequencing these clones represent 3 correctly fused cdna fragments, which are mint, alpha a - crystallin - binding protein i ( alphaa - crybpl ), and nuclear receptor co - repressor 1 ( n - corl ), respectively
鑒于mwt基因編碼區較長,共有10799個堿基,故此我們將mint分為六段,分別命名為fi一f6 ,本研究以其中的f5 ( 222e959 )和f6 ( 296s576 )片段為研究對象,將h者分別插入pgb盯7載體中,結果顯示: mintfs可與核受體輔助抑制因子1階cori ) , o晶狀體蛋白結合蛋白1hlphatcrybp入及mw加互作用,而f6可與igm的重鏈恆定區、泛素結合酶2l6和一個未知功能的新的蛋白基因進行結合。Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion
T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用, t細胞在發揮抗瘤效應(分泌細胞因子和直接殺傷)之前必須先經過活化,體內專職抗原提呈細胞( apc )細胞並使其活化,樹突狀細胞( dendriticcell , dc )為t細胞的激活提供雙重信號, t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后,通過tcr - cd3復合體傳遞抗原特異性識別信號(第一信號) ,以cd28為主的t細胞表面輔佐分子識別dc表面b7分子,傳遞非特異性協同刺激信號(第二信號) ,在機體抗腫瘤免疫應答中處于核心地位。分享友人