細胞劑量 的英文怎麼說
中文拼音 [xìbāojìliáng]
細胞劑量
英文
cytolytic dose- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 劑 : Ⅰ名詞1 (藥劑; 制劑) a pharmaceutical or other chemical preparation 2 (某些有化學作用的物品) a...
- 量 : 量動1. (度量) measure 2. (估量) estimate; size up
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
- 劑量 : [物理學] [醫學] dosage; dose; dosis劑量槽 dosage bunker; 劑量測定(法) dosimetry; health work; ...
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Methods the milk volume, morphology of mammary gland, serum prolactin level and pituitary acidophil number in lactation rats and the growth improvement in suckling mice were observed after administrating various dosages of maidang rutong granules to lactation rats by gastric gavage
方法哺乳期大鼠灌胃給予不同劑量的麥當乳通顆粒后,觀察其泌乳量、乳腺組織形態、血清泌乳素水平和垂體嗜酸性細胞數量的變化,以及對乳鼠生長的促進作用。Comprehensive cellular responses was found in human amnion fl cells following exposure to low concentration of mnng, such as the lowering of dna replication fidelity resulted from alteration of dna polymerase profile ; activation of a lot of transcription factors, such as api, creb, nf - kb etc ; clustering of egfr ( epidermal growth factor receptor ) and tnfr ( tumor necrosis factor receptor ) and activation of camp - pka - creb and jnk / sapk signal pathways
我們發現,低劑量mnng處理后的人羊膜fl細胞有廣泛的細胞反應,並有多個信號轉導通路的激活和基因表達的改變。例如dna復制保真度下降, dna聚合酶譜發生改變,應用報告基因技術和底物磷酸化檢出技術證明細胞一系列轉錄因子如ap1 、 creb 、 nf b等被激活,細胞表面受體如表皮生長因子受體、腫瘤壞死因子受體發生聚簇,細胞信號轉導通路camp - pka - creb和jnk sapk被激活。Effects of low - dose capsaicin on l - type calcium current in guinea pig ventricular myocytes
小劑量辣椒素對豚鼠心室肌細胞l -型鈣電流的影響At very high doses of radiation, neutrophils failed to respond significantly to chemotactic stimuli
很高輻射劑量時,中性粒細胞對趨化刺激物無明顯反應。Abstract : the anti - inflammatory effect of n - butanol extract of xanthocerassorbifolia bunge ( bex ) was studied in this paper. the ear edema resulted from dimethyl benzene, paw edema induced by carrageenin, the increase of vascular permeability caused by acetic acid, the chemotaxis of wbc induced by cmc and the weight of cotton granuloma in mice and hind paw edema induced by fresh egg white in rats were inhibited significantly by ig bex daily for 7 days, respectively. the carrageenin - induced paw edema was also inhibited markedly in adrenal - ectomiced mice. no changes in weight of adrenal and the concentration of vitamin c were observed, indicating that the anti - inflammatory effect of bex was not related to pituitary - adrenal system
文摘:文冠木正丁醇提取物對二甲苯致小鼠耳腫脹、蛋清致大鼠足腫脹、角叉菜膠致小鼠足腫脹、醋酸致小鼠腹腔毛細血管通透性增加、小鼠羧甲基纖維素囊中白細胞遊走、小鼠棉球肉芽腫生長均有顯著的抑制作用,同樣劑量下,文冠木正丁醇提取物對角叉菜膠致去雙側腎上腺小鼠足腫脹仍有顯著的抑制作用,且對小鼠腎上腺重量及腎上腺中維生素c的含量沒有明顯影響。Radiation protection - performance criteria for service laboratories performing biological dosimetry by cytogenetics
輻射防護.進行細胞遺傳學生物劑量測定的工作實驗室的性能標準While in hepatocirrhosis tissues, the molecule expressed both at membrane and in cytosol, and the membrane expression increased, it suggested a compensative mechanism
結果發現,芒果貳對bel一7404人肝癌細胞的增殖有明顯抑制作用,且其作用隨劑量的增大和作用時間的延長而增強。Effects of low dose fractionated irradiation on spleen on function of cellular immune in patients with esophageal carcinoma with radiotherapy
低劑量分次照射脾臟對食管癌放療患者細胞免疫功能的影響Generally speaking, less dosage will be relatively safe as compared with large dosage, which may induce pathological changes in the cells tissue and the hemal system
一般來說,小劑量對人體無大損害,而大劑量可導致組織細胞破壞及血液系統等發生病變。Bha cell differential agent is prepared with japanese macromolecular - energy plant extracting technology, which is edible and quite good at differentiating melanocytes
Bha細胞分化劑,由日本高分子能量植物提取技術方法提取,可食用的產品,有極強的分化黑色素細胞能力Method of peripheral lymphocydte micronucleus assay for estimating doses exposed
淋巴細胞微核估算受照劑量方法Sp2 / 0 myeloma cells are fused with spleen cells of balb / c mice ( the ratio is 1 : 10 ) immunized with at - by routine method. positive clones are detected by elisa
Sp2 / 0細胞和免疫脾細胞按1 : 10比例融合,融合劑peg分子量為1500 ,陽性克隆篩選採用三步進行。It uses a combination of a photosensitizing agent silicon - pathalocyanine, pc4 and strong visible light. first of all, the photosensitive pc4 is loaded into the cancer cells. when the pc4 is exposed to bright light, it increases the production of no and other oxidative species such as oh and o2 inside the cells, which leads to cell apoptosis disintegration and even cell death
首先,將光敏感性的pc4注入病人身體內,由於pc4染劑非常容易和不健康的細胞結合,這些不健康的細胞例如癌癥細胞在結合pc4活化性染劑后且又曝露在亮光下時,細胞內一氧化氮no及其它氧化物如氫氧離子oh -或過氧離子o2 -在細胞內的產生量會增加,因而導至此不健康的細胞萎縮,甚至死亡2 。Mdr1 express product p - glycoprotein was detected by immunocytochemical method and flowcytometry. the cytotoxicity and multidrug resistance reversion effect of tea polyphenol was examined by mtt assay in mcf - 7 and mcf - 7 adr carcinoma cell lines, and compared with pgp inhibitor quinidine. the pgp expression of mcf - 7 adr was strongly positive, the positive rate was 15 % ; the pgp expression of mcf - 7 was negative, the positive rate was 1. 8 %. ic50 of tea polyphenol to mcf - 7 and mcf - 7 adr is 115. 2g ml and 207. 6g ml respectively. ic50 of quinidine to mcf - 7 and mcf - 7 adr is 129. 8mol l 42. 1g ml and 94. 1mol l 30. 5g ml respectively. tea polyphenol and quinidine changed little toxicity of adriamycin to mcf - 7, but tea polyphenol and quinidine improved the sensitivity of mcf - 7adr to adriamycin significantly. immunocytochemistry and flow cytometry can detect p - glycoprotein expression level qualitatively and quantitatively. tea polyphenol is not only an anti - tumor agent, but also a multidrug resistant modulator similar as quinidine. tea polyphenol is advantageous for its little toxicity in tumor treatment
用免疫組化法和流式細胞儀對腫瘤細胞系mcf - 7和mcf - 7 adr的p -糖蛋白表達水平進行定性定量研究。用噻唑藍比色法mtt研究茶多酚的細胞毒性及其對耐藥性的逆轉作用,並與pgp抑制劑奎尼定進行了比較。免疫組化法檢測p -糖蛋白表達水平, mcf - 7 adr呈強陽性,而mcf - 7呈陰性流式細胞儀定量檢測結果mcf - 7 adr細胞系細胞陽性率為15 % , mcf - 7細胞系細胞陽性率為1 . 8 % 。Our previous studies demonstrated that agmatine not only reduced the amplitude of action potential ( apa ), maximal rate of depolarization ( vmax ), velocity of diastolic ( phase 4 ) depolarization ( vdd ), and rate of pacemaker firing ( rpf ), but also prolonged 90 % duration of action potential ( apd90 ) in a concentration - dependent manner
我們先前的實驗證明,胍了胺可劑量依賴性地抑制兔竇房結起搏細胞的0相最大上升速度( v _ ( max ) ) ,動作電位幅度( apa )和舒張期除極化速度( vdd ) ,起搏細胞放電頻率( rpf ) ,而且能延長90動作電位時程( apd _ ( 90 ) ) 。The characteristics of this method are : a, directly counting cell number without the influence of the metabolic state of the cells ; b, discrimination of target cells from effector cells in cell - mediated cytotoxicity assay ; c, less treatment step, and free - radioactivity ; d, high sensitivity and reliability. 2, using the above assay, immunofluorescent labeled technique, and flow cytometry, the pbmc proliferation, apoptosis, necrosis, cell cycle, activation, cytokines and membrane marker were detected. the results showed that the number of pbmc reduced, but the activity of pbmc increased dose - dependently ; the reduction of cell number resulted from necrosis and apoptosis ; the supernatant of k562 cell lines were not able to block the cell cycle, but to promote it ; the ratio of t cell subset and the expression of thl and th2 cytokines increased
結合以上創建的方法和免疫熒光流式細胞術,用k562細胞株可溶性分泌物(上清)對外周血單個核細胞( pbmc )進行培養以模擬體內微環境,然後分別從細胞增殖、凋亡、壞死、細胞周期、活性、細胞因子和表面抗原表達等方面進行研究,結果發現用腫瘤上清培養的pbmc細胞數量下降明顯,但同時對其有激活作用,且呈劑量依賴性;細胞數的下降主要是由細胞壞死和凋亡引起的,腫瘤上清對細胞周期沒有阻斷作用,反而略有促進作用; t細胞亞群比例增加,並促進表達th1 、 th2細胞因子。The results showed that in the beef cattle fed with chinese medicine additive, daily gain, number of lymphocyies and glucose and calcium concentrations in the blood were significantly increased, while npn content was decreased, some indexes, such as number of leucocyte, feed conversion rate and digestive rate of nutrients, had a tendency to rise, but there were no significant differences between treatment and control groups
結果表明,肉牛日糧中添加中藥飼料添加劑,可顯著提高日增重、血液中淋巴細胞數量、血糖和血鈣含量,非蛋白氮含量顯著下降;血液中白細胞、分葉細胞、採食量、飼料轉化率、各養分消化率均有上升趨勢,但組間無顯著差異。The present studies aimed to find the responses of neurons and glias in the target and other brain areas of the linear accelerator - irradiated rats. in the first experiment, time - dependent neurons changes in the brain after hemispheric irradiation at an single - fraction maximal dose of 20 gy were observed by investigating the expression of an immediate early gene, fos protein. the results shown : compared with that of the un - radiated rats, the expression of fos protein in the irradiated brain decreased distinctly 24 hours and 1 week after irradiation
首先,利用即刻早期基因fos的表達,做了同一照射劑量( 20gy )照射大鼠半腦后不同存活期間( 1d , 7d , 14d , 2ld , 28d )大鼠全腦神經元動態變化的觀察,發現:受照射后1d 、 7d大鼠腦內各部位fos蛋白表達均明顯減少,隨著時間的延長,其fos免疫反應性細胞數量逐漸增加,照射后28d ,延髓、第四軍醫大學碩士學位論文腦橋內hs免疫陽性細胞數量恢復並超過正常對照組水平,但中腦、間腦及端腦內未恢復到正常對照組水平。The originalities of this paper are : 1, development of a a flow cytometry - based assay for quantitative analysis of cellular proliferation and cytotoxicity in vitro ; 2, the soluble secretion of k. 562 cell lines reduce the number of pbmc, but promote the activity of pbmc in dose - dependent manner ; 3, soluble secretion of k562 cell lines can induce the no production by pbmc, but no only plays a part of the role of soluble secretion of k562 cell lines ; 4, establishing a in vitro model and giving some parameters for sreening and appraising anti - tumor medicine
本研究的創新點在於: l 、建立了用流式細胞術定量測定細胞增殖和細胞毒性的直接檢測技術; 2發現k562可溶性分泌物劑量依賴性地使pbmc細胞數量減少但活性增加; 3 、 k562可溶性分泌物能誘導pbmc產生no ,但是no的作用並不等同於腫瘤上清的全部作用。 4 、為抗腫瘤藥物篩選提供了一個體外模型,並明確了一些篩選指標。On the basi s of these results, time - dependent glias changes in the brain were observed with the same model by investigating the expression of s - 100 protein, a specific marker for glias, mainly for astrocytes. our results shown : compared with those of the unradiated rats, the number of s - 100 protein immunoreactive positive glial cells in the brains of the irradiated rats increased gradually. more s - 100 - positive glial cells with multiple long processes and hypertrophic cell bodies were also observed in these areas
在此基礎上,又做了同一照射劑量( 20gy )照射大鼠半腦后不同存活期間( id , 7d ; 14d , zld , 28d )大鼠全腦s 100動態變化的觀察,發現其規律如下:在上述時間點大鼠腦內各部位卜刁m蛋白免疫反應細胞數量進行性增加,伴有s 100免疫陽性細胞的胞體逐漸增大和交起增多,與正常對照組具有明顯的差異。分享友人