細胞基因重排 的英文怎麼說
中文拼音 [xìbāojīyīnzhòngbèi]
細胞基因重排
英文
t-cell gene rearrangement- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 因 : Ⅰ動詞[書面語] (沿襲) follow; carry on Ⅱ介詞1 [書面語] (憑借; 根據) on the basis of; in accord...
- 重 : 重Ⅰ名詞(重量; 分量) weight Ⅱ動詞(重視) lay [place put] stress on; place value upon; attach im...
- 排 : 排構詞成分。
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
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Methods : the rearranged gene fragment coding tcr y v region of the jurkat cell line was obtained by rt - pcr technique the pcr product was cloned into the eukaryocytic expressive vector pcdnas to construct pcdna3 / tcr y. after confirmed by sequncing. pcdnas / tcr y plasmids were amplified in bacteria extracted by alkaline lysismethod
方法:本文採用rt ? ? pcr的方法擴增jurkatt淋巴瘤細胞特異性重排的tcr可變區基因片段,克隆到真表達載體pcdna _ 3中,經序列測定無誤后,堿裂解法大量提取質粒,制備dna疫苗。In recent years, studies indicated these molecular markers mainly involved : oncogenes and tumor - suppressor genes mutate or rearrange in some thyroid neoplasms ; the exceptional increasing on the activity of telomerase ; the special proteins which are related to cell cycle regulation or adhesion express excessively ; as well as some special matter which is discovered recently
近年研究表明這些分子標志物主要涉及癌基因或抑癌基因的突變或重排;端粒酶活性的異常增高;一些與細胞周期調控或與粘附有關的特殊蛋白的表達;以及一些新發現的特異物質。Objective the origin and the nature of the hodgkin and reed - sternberg ( h / rs ) cell of hodgkin ' s lymphoma ( hl ) has been attracting a lot of medical researchers engaged in studying it, for its character by scattered large atypical cells residing in a complex admixture of inflammatory cells. great improvement has been made since a new method of isolation of single h / rs cells from a frozen section had been set up by kuppers in 1994, and many studies have approved of the b - cell derivation of h / rs cell. lt has been reported that h / r - s cells might partly be originated from b - cell in our research before, but at the same time, we also found that only 18. 8 % of h / rs cells express cd20, 31. 3 % of immunoglobulin heavy chain ( igh ) rearrangement have been revealed
目的霍奇金淋巴瘤( hodgkin ' slymphoma , hl )由於它的惡性腫瘤細胞? h rs細胞一般只佔腫瘤組織的極少部分(不到1 ) ,且散在分佈在背景細胞間,因此對于h rs細胞的來源和性質研究一直是人們探索的目標。 1994年德國科隆大學k ppers等發展了一種從冰凍組織切片上用顯微操作儀挑取單個h rs細胞的顯微切割方法進行h rs細胞基因分析后,人們對h rs細胞來源的研究有了突破性的進展,多數支持b細胞來源。我們的前期研究也支持部分h rs細胞為b細胞來源,但我們發現只有18 . 8的h rs細胞表達cd20 , 31 . 3的hl檢測到igh基因重排克隆性條帶。The rearrangements of immunoglobulin heavy chain and t cell receptor genes in patients with acute nonlymphocytic leukemia
基因重排與急性非淋巴細胞白血病的相關性No recipient of group a ( without any treatment, n = 5 ) or group b ( treated with adgfp, n = 4 ) died within three weeks after transplantation and severe acute rejection ( massive periportal infiltrate, endothelilitis, damage to biliary epithelium and severe tissue destruction ) was confirmed by pathological examination of the graft. in contrast, all recipients of group c ( treated with adhuctla4 - ig, n = 5 ) achieved lohg - term liver allograft survival ( > l50d )
35 ,屍0刀5八而灌注攜帶融合基因a個ig的重組腺病毒組組, fi ? 5 )受體鼠均能獲得長期生存( 150天) ; a組與c組間、 b組與c組間,生存期均有顯著性差異』 ( p 0刀1人a組與b組,在術后8天行移植肝活檢,病理學檢查證實:移植肝均發生嚴重的細胞性排斥。分享友人