細胞核受體 的英文怎麼說
中文拼音 [xìbāohéshòutǐ]
細胞核受體
英文
nuclear receptor- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 核 : 核構詞成分。
- 體 : 體構詞成分。
- 細胞核 : nucleus; caryon; cyteblast; cell nucleus
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
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Detection of fibroblast growth factor receptor 3 gene mutation at nucleotide 1138 site in congenital achondroplasia patients
先天性軟骨發育不全成纖維細胞生長因子受體3基因1138位核苷酸點突變的檢測We hope that our study will provide us with more comprehensive knowledge of the mechanisms of immune regulation and the roles that dc and complement play in innate and acquired immunity, as well as to lay a foundation for further exploration of the roles dc play in antigen - specific immune responses and immune tolerance from a new perspective. part i expression of complement receptors and complement - associated molecules on dendritic cells derived from distinct - origin at different stages of development two subsets of dendritic cells were generated from precursor cells isolated by means of magnetic cell separation system
曰補體受體及其相關分子在modc上的表達不同分化階段的單核細胞衍生性dc ( monocytes一deriveddc , modc )的誘導:將新鮮分離的單核細胞mo ,在含有gm一csf和工l一4培養體系中誘導5一7d ,即分化為未成熟modc ;對培養至sd的未成熟modc ,用tnfa刺激zd ,即分化為成熟modc ;此時再用lps刺激24h ,即為活化的modc 。At rest, the heterodimeric rel / nf - k b complex is located in the cytoplasm bound to an inhibitory factor, i k b. upon stimulation, i k b is phosphorylated and degraded, free nf - k b then translocates into the nucleus where it binds to k b site to regulate transcription
靜息時, re皿4bh聚體與抑制蛋白kbs結合,在細胞漿中保持無活性。受到刺激, ikb分子迅速磷酸化並降解,釋放nf兒b轉位入核,通過與kb位點結合調節轉錄。The process that led to dolly began with the transfer of the nucleus of an adult cell to an unfertilized egg taken from a donor animal by a process known as cell fusion
多利誕生的過程是這樣開始的:通過一個叫細胞合成的過程,把一個成體細胞核移植到一個取自供體動物的未受精的卵子上。Chemotaxis mediated by chemokine receptors, such as cxcr4, play a key role in lymphocyte homing and hematopoiesis as well as in breast cancer metastasis. we have previously demonstrated that ? - arrestin2 functions to attenuate cxcr4 - meidated g protein activation and to enhance cxcr4 internalization. here we further show that expression of ( - arrestin2 in both hela and hek293 cells significantly enhanced the chemotactic efficacy of stromal - cell derived factor 1 ( ( sdf - 1 ( ), the specific agonist of cxcr4
- arrestin2是趨化因子受體的一種重要的調節蛋白,本研究工作發現在hek - 293或hela細胞中升高- arrestin2的表達水平會顯著增強cxcr4介導的趨化作用,反之當- arrestin2的表達被它的反義核苷酸或rnai所抑制, cxcr4介導的趨化作用則被明顯抑制。Reconstruction of mouse embryos with chemically enucleated oocytes
化學去核卵母細胞為受體的小鼠體細胞核移植Translocation from endocytic compartments to the cytosol is the essential and rate - limiting step in the intoxication process of most toxins such as ricin, diphtheria toxin, shiga toxin and pseudomonas exotoxin ( pe ). a number of these toxins are transported to trans - golgi network ( tgn ), and in many cases such transport to the tgn is required for the translocation and cytotoxicity. in deed, 5 % of the ricin endocytosed by cells has been shown to reach the tgn
蓖麻毒素進入細胞的機理不甚明了,一般認為是rtb先與細胞膜受體結合,主要經過受體介導的內吞作用進入吞噬體,然後沿著內體、高爾基體、內質網等逆向分泌途徑,有序地運輸到內質網,最後從內質網轉位進入細胞漿,在胞漿內攻擊核糖體,從而抑制蛋白質的合成,導致細胞死亡。Within 2h isolation from the follicle 100 % of oocytes underwent germinal vesicle breakdown and both the nucleolus and the nuclear envelope disappeared. after culturing for 6 h, prometaphase occurred in 90 % oocytes
本研究旨在探索一種嶄新的、化學試劑誘導去核卵母細胞為核受體的、無透明帶的、手工體細胞核移植方法。Ultrastructurally, karyopyknosis and karyolysis occured in lymphocytes, and the mitochondria, rough endoplasmic reticulum of lymphocytes in the immune organs were damaged. the nucleus were deformity, the rmtochondrial and rough endoplasmic reticulum were swelling, and the ribosomes were shed in reticular cells of thymus in zinc - deficient ducklings
超微結構顯示缺鋅組淋巴細胞核固縮或溶解,線粒體、粗面內質網受損;胸腺網狀細胞核受損,粗面內質網擴張,線粒體腫脹、嵴斷裂。The isozyme patterns of spermary and heart is same to hepatopancreas, not show a specificity dominance isozyme patterns, spermary exist dominance isozyme patterns at 0. 29 of rf value, the heart exist dominance isozyme patterns at 0. 32 of rf value
結果表明:銅、鎘聯合作用10d后各細胞器均表現出受損現象,其中細胞核與線粒體均表現出形態上的改變,肌纖維則受損相對較輕。The organelles with membranous structure in myocardial cells and germ cells were easily damaged, such as mitochondria, nucleus, golgi body ( gb ) and lysosome
細胞內容易受到損傷的主要結構是具膜的細胞器,如線粒體、細胞核、高爾基體及溶酶體等。Some transgenic plants harboring the gfp tnos vector also exhibited inhibited expression of gfp, and northern blots also revealed that most gfp mrnas transcribed from tnos accumulated in the nucleus and was not transported into the cytoplasm
獲得了含有gfp - tnos表達載體的轉基因本生煙,在部分轉基因株系中gfp基因的表達受到抑制。 northern分析顯示: gfp - tnos載體所表達的gfp基因產物多數滯留在細胞核內部,不能被運送到細胞質中。The following research areas will be involved in the project : ( 1 ) mechanism of hereditic factors and its function in chinese type 2 diabetes ; ( 2 ) metabolomics on the cell stress and its nutrition intervention in the type 2 diabetes ; ( 3 ) mechanisms of metabolic nuclear receptors in the process of insulin resistance and type 2 diabetes onset ; ( 4 ) roles of signal transduction molecules, lipid metabolic disorder to insulin resistance ; ( 5 ) type 2 diabetes development and role of pathological changes of blood vessels ; ( 6 ) abnormal insulin secretion, apoptosis and type 2 diabetes ; ( 7 ) function of molecular network of type 2 diabetes progression
本項目擬開展以下研究工作: ( 1 )中國人2型糖尿病發生過程中遺傳因素的發現及其作用機制; ( 2 )細胞應激在中國人2型糖尿病發生過程中的作用機制及其營養干預的代謝組學; ( 3 )代謝性核受體在胰島素抵抗和2型糖尿病發病中的作用機制; ( 4 )細胞信號轉導分子、脂代謝紊亂與胰島素抵抗的關系; ( 5 ) 2型糖尿病發展過程與血管病變; ( 6 )胰島素分泌異常、細胞凋亡與2型糖尿病; ( 7 ) 2型糖尿病發生過程中的分子網路與作用機制。C - kit is a receptor tyrosine protein kinase on the cellular membrane, while c - myc is a transcription regulatory factor in the nucleus
Kit是位於細胞膜上的受體酪氨酸蛋白激酶, myc是位於細胞核內的轉錄調節因子。Maturation rates of 9 types of reconstructed gv oocytes were not differed with maternal age. after maturation of reconstructed gv oocytes, the percentages of pronuclear - stage embryos and 2 - cell embryos developed from 9 types of reconstructed oocytes by ivf or artificial activation were not influenced by cytoplasmic or nuclear changes resulting from oocytes of different age groups of mice
不同年齡段小鼠進行gv互換所形成的9種重組卵母細胞,在經人工活化或體外受精后,形成原核期胚和2 -細胞期胚的比率並不因不同年齡小鼠卵母細胞所帶來的細胞質或細胞核的改變而受到影響。Most ones were these disorganized partly, mainly, till all, mitochondria fused by itself, circled, mitochondria membrane broke and disintegrated
處理20d后,細胞核與線粒體受損情況加重,主要表現在,細胞核膜間距加大,異染色質疑聚,常染色質電子密度降低。This study were designed to investigate development potency of the reconstructed embryos of black bear - cat inter - species nuclear transfer in vitro / vivo, to develop the principle and technology of somatic nuclear transplantation in inter - species of mammalian and to study the mechanism of coordination between cell nuclear and cytoplasm. somatic nuclear transplantation technology has been used to establish stem cell from different animals, which can provide materials to treat various diseases
本研究運用體細胞核移植的原理和技術,以六月齡雌性黑熊的成纖維細胞為供核體,去核未受精家貓成熟卵母細胞為受體,構建種間核移植重組胚胎,研究種問體細胞核移植胚胎的構建方法和重組胚胎的體內外發育潛能及其影響因素。This study were designed to investigate development potency of the reconstructed embryos of rat - mouse and rat - bovine inter - species nuclear transfer in vitro / vivo, to develop the principle and technology of somatic nuclear transplantation in inter - species of mammalian and to study the mechanism of coordination between cell nuclear and cytoplasm. somatic nuclear transplantation technology has been used to establish stem cell from different animals, which can provide material to treat various diseases
本研究運用體細胞核移植的原理和技術,以成年大鼠的成纖維細胞為供體,去核小鼠和牛成熟卵母細胞為受體,構建種間核移植重組胚胎,研究種間體細胞核移植胚胎的構建方法和重組胚胎的體內外發育潛能及其影響因素。This means changing the genome of either a gamete ( sperm or egg ) or a zygote ( a single cell formed either by fertilisation or by somatic cell nuclear transfer, a. k. a. cloning ) so that people are born with a designed genetic alteration
這意味著改變配子(精子或卵子)或合子(由受精或體細胞核移植形成的一個細胞,核移植也稱克隆) ,以至於人是由一種設計了的遺傳變化而出生。On november 14th nature, one of the world ' s leading scientific journals, published a paper about the creation of embryonic stem cells using a technique called somatic - cell nuclear transfer ( basically, taking the nucleus from a body cell and putting it in an unfertilised egg )
世界前沿科學期刊《自然》于其11月14日的雜志上刊登了一篇關于如何通過體細胞核移植製造胚胎幹細胞的論文(簡單的說,體細胞核移植就是從體細胞提取細胞核後放入未受精卵中的過程) 。分享友人