肽能受體 的英文怎麼說

中文拼音 [tàinéngshòutǐ]
肽能受體 英文
peptidergic receptor
  • 肽 : 名詞[化學] （有機化合物） peptide
  • 能 : 能名詞（姓氏） a surname
  • 體 : 體構詞成分。
  1. [ conclusion ] taken together, these data suggested that two peptides gwyydal and vasavfysalve were effective mimickers of vegf and these peptides maybe potent inhibitors of kdr and offer a hope for the construction of tumor vaccine

    而且該模擬抗原表位可能與huvec上表達的vegf受體結合，從而抑制了vegf的促huvec生長作用。這為進一步定位vegf抗原表位，研究vegf受體結合抑制肽，設計腫瘤疫苗提供了有力的基礎。
  2. At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells

    但是，學者們發現這一療法存在著如下的缺陷：單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用，且有誘導免疫耐受的潛在危險，有時反而會促進腫瘤的生長；事先需對患者的hla單倍型進行鑒定，以確定ctl表位與hla單倍型是否匹配，目前尚缺乏能與所有hla單倍型相匹配的ctl表位，從而限制了這一療法的應用；這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞，但對腫瘤細胞的殺傷能力較弱：這種l表位抗原肽缺乏cd4汀h細胞相關的表位，因此，不能誘導有效的th細胞免疫應答。
  3. Bradykinin powerfully stimulates nociceptors, and an antagonist that blocks its receptors would certainly prevent those receptors from activating nociceptors

    那麼，能阻斷緩激肽受體的拮抗劑，必定可以防止這些受體造成的痛覺受器活化。
  4. Animal growth hormone ( gh ) is a very important protein hormone which is secreted by the anterior pituitary cells and plays many important roles on animals, such as regulating somatic growth and stimulating appetite, affecting various metabolic activities and improving the food transformation rate, etc. although gh has so many functions, it is limited in the application and functional researches because the natural growth hormone content is very low and difficult to purify

    動物生長激素（ growthhormone ， gh ）是由腦垂體間葉細胞分泌的一種多肽激素，具有調節生長發育，參與體內代謝調節，增進食慾，提高食物轉化率等作用，然而垂體中生長激素含量極低，分離純化比較困難，使得生長激素生理功能的進一步研究和應用受到限制。
  5. Rabbits in the immunized group ( n = 7 ) were immunized monthly for one year with synthetic peptide correspo nding to the second extracellular loop of the 1 - adrenoreceptor and adjuvant

    用1腎上腺素能受體細胞外二環肽段和佐劑對免疫組動物進行每月一次免疫，總時程為一年。
  6. However, there i s no direct evidence about the influences of vnp on the proliferation of other vascular smooth muscle cells. three receptors subtypes for natriuretic peptides have been identified, the natriuretic peptide receptor ( npr ) - a, npr - b and npr - c. the npr - a and npr - b are membrane - bound guanylate cyclase coupled to production of 3 ", 5 ' - cyclic guanosine - 7 - monophophate ( cgmp )

    鈉尿肽受體（ natriureticpeptidereceptors ， nprs ）有a 、 b 、 c三個亞型，其中a 、 b （ npr - a 、 b ）受體是鳥苷酸環化酶（ gc ）耦聯受體，與配體結合后引起細胞內cgmp水平升高，而c受體不與gc耦聯，主要通過結合和內化（ internalize ）鈉尿肽而發揮清除受體的功能。
  7. Part ii screening of tnfa mimotopes from phage display peptide library : based on the results of screening tnfa binding - peptides, we have tried to use neutral tnfa mcab j1d9 as target to screen tnfa mimotopes from c7c phage display peptide library, which may be another form of antagonist for tnfa, and the mimotopes were identified by sandwich elisa. after 3 rounds of screening, we got 9 phage clones identified as positive clones which can bind with mcab j1d9. we also identified the binding between mimotopes and tnf receptor by competitive elisa, and the results showed strongly binding. the amino acid sequence results shown three different sequences : c - rrpaqsg - c - nkhnrki - c and c - rgmsrki - c

    在對噬菌體環七肽庫進行三輪親和性篩選后，隨機挑選20個噬菌體克隆， elisa鑒定出9個陽性克隆，經dna測序推出三種氨基酸序列： c - rrpaqsg - c 、 c - nkhnrki - c和c - rgmsrki - c ，其中優勢克隆序列為c - rrpaqsg - c ；鑒定結果顯示陽性克隆能夠與tnf受體結合，並且能夠阻斷tnf與受體的結合，提示篩選得到的環七肽克隆展示肽具有tnf的抗原性及與tnf受體結第一軍醫大學顧士學位論文合的特性，為tnfa表位模擬肽。
  8. N - acetylcysteine is the acetylation of l - cysteine as the donor of sulfhydrylgruppe ( - sh ), not only has the great antioxidation, but also supplies the reduced glutathione in the body efficiently, and pretects the cell not to be injuried. the preventive effective of n - acetylcysteine against acute lung injury has been supported by the animal experiment and clinic research

    N -乙酰半胱氨酸是l -半胱氨酸的乙酰化物，作為巰基的供體，不僅具有強大的抗氧化作用，還能有效補充機體內降低的還原型谷胱苷肽，保護細胞免受損傷，其對急性肺損傷的防治作用已獲得動物實驗和臨床研究結果的支持。
  9. Mekler idlis ( m - i ) pair theory suggests that each codon - directed amino acid residue in a sense peptide may make a specific pair - wise interaction with the corresponding complementary codon - directed residue in the complementary peptide. ahbs theory suggests also the parts between / in the proteins that are capable of interacting specifically. the interaction between receptor and ligand is the recognition and interaction between proteins. if the receptor is the sens e peptide, the ligand, which can specifically bind to it, must have one or several antisense peptides. these antisense peptides muat be located at the key place which has relationship with the function of the ligand

    Ahbs （反義同源盒）理論和分子識別理論描述了蛋白分子內和蛋白分子間可以特異結合的區域結構具有正義與反義的關系。受體與配體的相互作用實質上是蛋白質分子間的識別、結合和相互作用的過程。將受體看作是有義肽，那麼可與之特異結合的配體分子中可能存在一段或多段反義肽，而且其存在的部位是配體功能的關鍵位置。
  10. Seven - span transmembrane ( 7 - tm ) molecules constitute superfamilies of cell - surface proteins. they are receptors for small molecules. peptides, hormones and ions. they also act as ligands for mediating a variety of external signals to the cytoplasm

    它們主要作為一些小分子物質如肽類，激素，細胞因子和多種離子的受體，主要功能是介導細胞外信號傳遞和調節細胞的生物學功能。
  11. [ objective ] tumor angiogensis is a critical step for the growth and metastasis of solid tumors. vascular endothelial growth factor ( vegf ) is a specific and potent angiogenic factor that mediates vascularization by binding to the kinase domain receptor ( kdr )

    [目的]本實驗試圖通過能中和vegf生物活性的單抗從噬菌體隨機7肽、 12肽文庫中篩選一種能抑制vegf與血管內皮細胞表面受體kdr （ kinasedomainreceptor ）結合的vegf模擬短肽。
  12. It is one kind is passed with distinctive, the cellular film that mixes high in person accepts put oneself in another ' s position union, adjust the polypeptide that the cell grows to wait for much effect with other cell function kind material

    是一類通過與特異的、高親和的細胞膜受體結合、調節細胞生長與其他細胞功能等多效應的多肽類物質。
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