It is an important that bacteria contaminated vaccine in the biologicals production. we collected 703 samples of cell culture, virus cultivation and harvest which were contaminated by bacteria during poliovaccine production within two years. we checked these samples by bacteriological method and antibiotics sensitivity tests were done. it shows that 1 ) the main contaminated bacteria come from staphylococci, bacilli and streptococci of environment in the poliovaccine production. 2 ) it is effect that antibiotics to contaminated bacteria are doxycycline, albiotic, prescription 2, cefotaxime na salt, gentamycin, neomycin, aureomycin and erythromycin
在疫苗生產實踐中,細菌污染是影響疫苗質量和產量的關鍵性因素,筆者通過了兩年左右的時間,選取正常生產中零星細菌污染的細胞培養瓶、病毒培養瓶及收毒污染樣品等共703份,進行細菌學檢查,並對造成污染的主要細菌種類進行了各種抗菌藥物的耐藥性實驗,結果表明:我所
脊灰疫苗生產中主要的污染威脅來自環境中的葡萄球菌,潛在威脅是桿菌和鏈球菌;
強力黴素、林可黴素、配方2 、噻孢黴素鈉鹽、慶大黴素、新黴素、金黴素和紅黴素等抗生素對目前引起污染優勢細菌-葡萄球菌有明顯的抑菌效果,可作為疫苗生產后備抗菌手段參考
The complete nucleotide sequence of the mitochondrial genome of f. limnocharis was detailedly compared with those of 5 other amphibians. the nucleotide sequences of 22 trna encoded by 6 amphibians mitochondrial genomes were combined and aligned to the homologous sequences of the 11 veterbrate taxa. using teleosts as outgroup, the phylogenetic analyses results show that mp, nj and ml trees all strongly support the monophyly of living amphibians with respect to other living tetrapods and favor a sister group relationship for caecilians and salamanders
我們在測定了澤蛙線粒體全基因組序列的基礎上,與已知其它的5種兩棲類進行詳細的比較分析,同時選擇了11種高等
脊椎動物的線粒體全基因序列,以硬骨魚類做外群,用22個trna基因合併數據進行系統發生重建分析,結果表明mp 、 nj和ml樹都
強力地支持現生兩棲類動物為單系群並且蠑螈類和蚓螈類為姐妹群關系(自引導值分別為92 、 99 、 100 ) 。
The protein nucleic acid complexes were identified by autoradiography for 48 h. the psg5heo and igfbp - 6 promoter pcat vectors were transfected into cos - 7 cells with iipofectamin2000 ; these cos - 7 cells where treated with 1 jxm e2, with lonm tcdd and with both lonm tcdd and 1 jxm e2, individually ; the cat protein was examined by cat - els a. results : the congenital skeletal defects in fetal rats were induced with 10 - 15ug / kg tcdd or with 100 - 140 mg / kg ra with dosage - dependence effect. the igfbp - 6 mrna in rat calvaria tissue and mc - 3t3 - el cells were increased with tcdd and ( or ) ra, whereas the cell proliferation and igf - 2 mrna in mc - 3t3 - el cells was decreased in the status of e2
結果: tcdd在大鼠胚胎發育時期具有骨骼致畸作用,骨骼發育畸形包括:內翻足、
脊柱裂、顱面骨發育缺陷、無尾畸形等;隨著tcdd濃度的升高( 10一15林擴kg ) ,致畸率明顯上升( 14 . 7 %一24 . 6 % ) ; tcdd和ra聯合用藥可以增
強對大鼠骨骼發育的致畸效應; e :對成骨細胞內igf一2基因有正性調節作用,對igfbp一6基因有負性調節作用, tcdd可以抑制e :對細胞內xgf一2和igfbp一6的調節作用。
The distinguished scientist herr professor luitpold blumenduft tendered medical evidence to the effect that the instantaneous fracture of the cervical vertebrae and consequent scission of the spinal cord would, according to the best approved traditions of medical science, be calculated to inevitably produce in the human subject a violent ganglionic stimulus of the nerve centres, causing the pores of the cobra cavernosa to rapidly dilate in such a way as to instantaneously facilitate the flow of blood to that part of the human anatomy known as the penis or male organ resulting in the phenomenon which has been dominated by the faculty a morbid upwards and outwards philoprogenitive erection in articulo mortis per diminutionem capitis
傑出的科學家盧伊特波爾德布盧門達夫特168教授先生曾提出下述醫學根據加以闡明:按照醫學上公認的傳統學說,頸椎骨的碎折以及伴隨而來的
脊髓截斷,不可避免地會給予人身神經中樞以
強烈刺激,從而引起海綿體的彈性細孔急速膨脹,促使血液瞬時注入在人體解剖學上稱為陰莖即男性生殖器的這一部位。其結果是:在頸骨斷襲導致死亡的那一瞬間169 ,誘發出專家稱之為「生殖器病態地向前上方多產性勃起」這一現象。
Been hd, poolman rw, ubags lh, et al. clinical outcome and radiographic results after surgical treatment of post - traumatic thoracolumbar kyphosis following simple type a fractures. eur spine j, 2004 mar ; 13 ( 2 ) : 101 - 7
齊
強,陳仲
強,郭昭慶,等。
脊柱前方墊高-後方閉合截骨矯形術治療胸腰段
脊柱后凸畸形的初步報告。中華外科雜志, 2006 , 44 ( 8 ) : 551 - 555
Clinical observation on total glucosides of paeony combined with sulfasalazine in treatment of ankylosing spondylitis
白芍總甙聯合柳氮磺吡啶治療
強直性
脊柱炎臨床觀察
Effectively sparing spinal cord and parotid by imrt to npc patient
鼻咽癌適形調
強放療減少
脊髓和腮腺受量的物理劑量研究
Spondylitis ankylopoietica 35 cases treated by pubescent angelica and loranthus decoction
獨活寄生湯加減治療
強直性
脊柱炎58例
Summary of treatment with syndrom differentiation on tonic rachitis
強直性脊柱炎辨治掇要