腸動肽 的英文怎麼說
中文拼音 [chángdòngtài]
腸動肽
英文
proctolin-
Effects of yiqi kaimi recipe on gastrointestinal motility and neuropeptides in rats with colonic slow transit constipation
益氣開秘方對結腸慢輸型便秘大鼠腸動力和腸神經肽的影響Moreover, human ghrelin receptor exhibits a remarkable 50 % overall identity with human motilin receptor, therefore it was named as " raotilin - related peptide ". anatomical evidence showed that there are ascending and descending neuronal projections between pvn, bma and lower brain stem ( nts, dmx ), which participate in the regulation of gastric acid secretion and gastrointestinal motility. moreover, pvn is the center of appetite regulatory web
Pvn與低位腦干(延髓迷走復合體)及邊緣系統之間有密切的纖維聯系,且含有多種神經肽,參與胃酸分泌,胃腸活動等多種生理機能的調節,是影響消化道功能與攝食行為的重要中樞部分, pvn內胃動素可促進胃排空和攝食,而新發現的ghrelin /胃動素相關肽是否參與此核區對胃運動的調節機制及其可能的神經通路尚不明了。It was recognized as a brain - gut peptide since the peptide and its receptor exist in the central nervous system. previously, we demonstrated that motilin and motilides activates cells in paraventricular nuclei ( pvn ) reflected by increased gastric motility and induction of the immediate early gene c - fos in conscious rat, which suggests central motilin participates in the regulation of gastric motility. it was reported in 2001 that ghrelin is an appetite - stimu latory signal from stomach with structural resemblance to motilin
胃動素( motilin , mt )是由小腸上段粘膜內分泌細胞合成並分泌的22個氨基酸組成的腦腸肽,調節消化間期胃運動, pvn內給予胃動素和胃動內酯( motilides )可增強清醒大鼠胃運動,中樞微量注射胃動素可誘導pvn中立即早期基因c - fos的表達,提示中樞胃動素參與胃運動的調控,人ghrelin和胃動素之間有36的相似性,而且二者的受體之間有50的相似性,因而有人稱ghrelin為「胃動素相關肽」 。6 6 sjolund k, ekman r, lindgren s, rehfeld jf. disturbed motilin and cholycystokinin release in the irritable bowel syndrome. scand j gastroenterol 1996, 31 : 1110
5 5桂先勇,潘國宗,柯美雲,等.胃腸肽在應激所致結腸動力紊亂中的作用.中華醫學雜志1997 , 77 : 31And the fusion protein could been purified quickly by thiobond ? resin. this was key step to produce cmiv largely by fermentation. meanwhile, the structure of the mutation ii of cmiv showed a new way to design peptide of cecropin which have the targeting sequence to tumor cell
以上研究的意義: 1 、初步解決了抗菌肽cmiv突變體在大腸桿菌中高效可溶性表達的問題,為進一步大量生產cmiv基因突變體打下基礎; 2 、為進一步設計具有特異導向性的抗菌抗腫瘤cmiv突變體基因和表達以及以後進行動植物轉化打下基礎。分享友人