親細胞抗體 的英文怎麼說
中文拼音 [qīnxìbāokàngtǐ]
親細胞抗體
英文
cytophilic antibody- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 抗 : Ⅰ動詞1 (抵抗; 抵擋) resist; combat; fight 2 (拒絕; 抗拒) refuse; defy 3 (對等) contend with...
- 體 : 體構詞成分。
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
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It has been demonstrated that complement activating and cr2 cross - linking on b lymphocytes set up a bridge between innate and acquired immunity. the interaction of c3 and cd21 on b lymphocytes will benefit initiating immune response and regulating primary antibody response. cd21 / cd35 is important in the process of antibody avidity maturing, this is critical to b lymphocyte activation especially in the state of low antigen concentration
現己證實補體的活化以及b細胞表面crz的交聯在先天和獲得性免疫之間架起了重要的橋梁,表現為c3與b細胞cdzi的相互作用有利於啟動抗體應答反應,並對初級抗體應答反應有調節作用: cdzi cd35對于抗體的親和性成熟具有重要作用,在抗原濃度低的情況下,對于活化b細胞是至關重要的,而且mlgm (交聯有利於特異的低親和性b細胞對t細胞依賴性抗原和t細胞非依賴性抗原產生免疫應答。Purified fusion protein gst - hnadc3 was used as an immunogen to inoculate rabbits and the antibody against the gst - hnadc3 fusion protein was raised, and was purified by gst sepharose 4b affinity chromatography to remove the antibody against gst
Ptg誘導表達,超聲破碎細胞后,採用親和層析方法純化融合蛋白gst十nadc3 ,並以此為抗原免疫紐西蘭株白兔制備融合蛋白抗體。應用親和層析的方法對gst十nadc3融合蛋白抗體進行純化,以去除抗gst抗體。Anti - melatonin monoclonal antibodies of higher titer, affinity and good sensitivity were obtained by coupling mt to bovine serum albumin with formaldehyde and by immunizing mice with multifocal intra - dermal injections. we obtained 6 strains of hybridoma, all of them secreting specific antibodies to mt, we apply antibodies to determinate free mt inhuman serun with group - selective immunoassay technique. an inhibition curve for mt was obtained in the range of 50pg to30ng, and 1. 4ng of mt inhibited the value of the assay by half. we evaluate the specificity of antibodies by determination of cross - reactivity of several analogues, the moabs recognized mt but
通過將mt用甲醛作連結劑連結到牛血清白蛋白上sa採用皮下多點注射兔疫小鼠得到了高效價,高親和力,較好特異性的抗mt單克隆抗體,最後獲得了5株單克隆細胞株,都能分泌針對mt的特異性抗體,建立了選擇性基團免疫分析法,用制備的抗體測定了人血清中mt的含量,作了mt的抑制標準曲線,其抑制范圍從50pg ? 30ng ,半抑制量為1It has been demonstrated directly or indirectly - 7 - that ak auto ab is an important element in the immune network and plays a important role in maintaining physiological functions, clearing aged cells and metabolic products, regulating immune responses and protecting against infection. in some pathological states such as psoriasis and contact dermatitis, a certain serum level of the antibody could inhibit the progression of the diseases, and is beneficial to the recovery from the diseases. after a long time studies on the production and regulation mechanism of physiological and pathological auto antibodies, meanwhile, experiencing an intensive academic debating on whether naas a " horror autotoxicus " or a " gnothi seaution ( know yourself ) ", a common viewpoint has been achieved that naa is of clinical significance in the treatment of immunity diseases for it ' s function in the immune system stability, immunoglobulin y and polyclonal ak auto abs have been used in treating inflammatory dermatitis, and recombinant antibody is under investigating
抗角蛋白自身抗體( akautoab )是naa的重要組成部分,以往實驗通過雜交瘤技術、免疫親和層析技術和噬菌體抗體庫技術分別獲得單克隆akautoab 、健康人血清多克隆akautoab和基因工程人akautoab ,並對akautoab免疫學特性及在體生理和病理意義進行了廣泛的研究,直接或間接地發現akautoab是機體正常免疫調節網路的組成部分,在維護某些生理狀態的穩定、清理衰老細胞及代謝產物、調節免疫和抗感染等方面起到重要作用;在某些病理情況下(如銀屑病、接觸性皮炎等) ,體內akautoab的組分和滴度會發生變化,而正常水平的akautoab則有利於限制病情的發展,促進損傷的修復。The characteristics of quantum computing and the mechanism of immune evolution are analyzed and discussed. inspired by the mechanism in which immune cell can gradually accomplish affinity maturation during the self - evolution process, a immune evolutionary algorithm based on quantum computing ( mqea ) is proposed. the algorithm can find out optimal solution by the mechanism in which antibody can be clone selected, memory cells can be produced, similar antibodies can be suppressed and immune cell can be expressed as quantum bit ( q - bit ). it not only can maintain quite nicely the population diversity than the classical evolutionary algorithm, but also can help to accelerate the convergence speed and converge to the global optimal solution rapidly. the convergence of the mqea is proved and its superiority is shown by some simulation experiments in this paper
分析和探討了量子計算的特點及免疫進化機制,並結合免疫系統的動力學模型和免疫細胞在自我進化中的親和度成熟機理,提出了一種基於量子計算的免疫進化演算法.該演算法使用量子比特表達染色體,通過免疫克隆、記憶細胞產生和抗體相似性抑制等進化機制可最終找出最優解,它比傳統的量子進化演算法具有更好的種群多樣性、更快的收斂速度和全局尋優能力.在此不僅從理論上證明了該演算法的收斂,而且通過模擬實驗表明了該演算法的優越性Abstract : the characteristics of quantum computing and the mechanism of immune evolution are analyzed and discussed. inspired by the mechanism in which immune cell can gradually accomplish affinity maturation during the self - evolution process, a immune evolutionary algorithm based on quantum computing ( mqea ) is proposed. the algorithm can find out optimal solution by the mechanism in which antibody can be clone selected, memory cells can be produced, similar antibodies can be suppressed and immune cell can be expressed as quantum bit ( q - bit ). it not only can maintain quite nicely the population diversity than the classical evolutionary algorithm, but also can help to accelerate the convergence speed and converge to the global optimal solution rapidly. the convergence of the mqea is proved and its superiority is shown by some simulation experiments in this paper
文摘:分析和探討了量子計算的特點及免疫進化機制,並結合免疫系統的動力學模型和免疫細胞在自我進化中的親和度成熟機理,提出了一種基於量子計算的免疫進化演算法.該演算法使用量子比特表達染色體,通過免疫克隆、記憶細胞產生和抗體相似性抑制等進化機制可最終找出最優解,它比傳統的量子進化演算法具有更好的種群多樣性、更快的收斂速度和全局尋優能力.在此不僅從理論上證明了該演算法的收斂,而且通過模擬實驗表明了該演算法的優越性2 ) basis of upon studies, we have also designed and sythesized the mutation ii of the cmiv that been greatly changed in the 3 " of the gene comparing with nature cmiv : the ht gf3 ( the third loop region of htgf2 specifically binding to egfr receptor ) was fused to 3 " of gene of cmiv through a flexible linker. the gene of the mutation ii of cmiv was sequenced and clonged to the vector of ptxfus to fuse to the 3 " of gene of thioredoxin
二、在以上研究的基礎上,對cmiv抗菌肽的c端進行較大的改造,即將與腫瘤細胞過度表達的表皮生長因子受體( egfr )具有高親和性的因子多肽tgf _ 3通過疏水柔性接頭連接在抗菌肽cmiv的c端,設計完整的基因,並在大腸桿菌中利用ptxfus表達載體與硫氧還蛋白進行可溶性融合蛋白表達。H chain cdr3 region is thought to be the antigenic epitope of antibody of monoclonal antibody np30. therefore, anti - id antibody vaccine and antigenic epitope vaccine are important strategy in developing schistosomajaponicum vaccine
Fv基因,且其表達產物保留了抗體的親和性和特異性,有可能替代雜交瘤細胞分泌的單克隆抗體np30作為免疫檢測試劑。The ascites fluid antibody purified by 33 % ammonium sulfate is further purified by chromatography. the p24 affinity chromato - graphic column done to purify the bispecific antibody is in the brcn activated sepharose 4b. after washing the unspecific proteins, change the washing buffer and the anti - p24 / anti - human rbc type a bispecific antibody and the anti - p24 monospecific antibody are gained respectively
方法是先用硫酸綏鹽析,再過親和層析柱,即33飽和硫酸按沉澱后,透祈過夜,上p24抗原做配體的濱化氰活化的sepharose4b柱,流洗掉雜蛋白和抗人紅細胞單特異性抗體后,再洗脫並收集雙特異性抗體。During pregnancy mothers may become sensitized to platelet membrane antigens present on fetal platelets
在懷孕期內母親也許會對胎兒的血小板細胞膜上表達的抗體過敏。In the first part, we observed the changes of expressions of type i receptor of il - 1 in the rat and mouse brain after intraperitoneally administration of different kinds and doses antigens respectively. in the second part including two experiments we cloned rat il - 6r ' s genes by pcr, expressed them in e. coli dh5 a and cos - 7 cell, and produced il - 6r ' s polyclonal antibody which is proved having more high liter, affinity and specificity 1
第一部分採用不同種類和劑量的抗原刺激,分兩個實驗,觀察了大、小鼠腦內il - 1的i型受體表達的變化,探討了腦內參與免疫調控的核團和細胞類型;第二部分分兩個實驗,運用pcr技術克隆了大鼠il - 6r的基因並進行了原核和真核表達,制備了特異性高、親和力強和較高效價的抗il - 6r多克隆抗體,為進一步進行il - 6r的研究奠定了基礎。Study of the relationship of insulin receptor with insulin resistance in nondiabetic first - degree relatives of type 2 diabetes mellitus
2型糖尿病患者正常糖耐量一級親屬紅細胞膜胰島素受體變化及與胰島素抵抗的相關性分享友人