轉酮酶 的英文怎麼說
中文拼音 [zhuǎntóng]
轉酮酶
英文
transketolase-
Transketolase is the key enzyme of pentose - phophate pathway, catalyses transfer of a two - carbon fragment from a ketolase ( donor substance ) to an aldose ( acceptor substance )
摘要轉酮醇酶是磷酸戊糖途徑的關鍵酶，催化二碳單元在酮糖（供體）和醛糖（受體）間的轉移。The enzyme 5 - enolpyuvyl - 3 - phosphoshikimic acid synthase ( epsp synthase ; ec2. 5. 1. 19 ), encoded by anoa locus, is a key enzyme present in microorganisms and plants where it has a function in the biosynthesis of aromatic amino acids. glyphosate ( n - phosphonomethyl - glycine ) is an effective non - selective, broad spectrum, postemergence herbicide, which has been shown to inhibit epsp synthase activity in a competitive manner. glyphosate tolerant plants can be mediated by either overproduction of the target enzyme or by the presence of an altered enzyme
植物和微生物芳香族氨基酸生物合成過程中的一個關鍵酶? ? 5 -烯醇丙酮莽草酸- 3 -磷酸合成酶（ epspsynthase ； ec2 . 5 . 1 . 19 ）由aroa基因編碼，該酶受廣譜滅生性、內吸傳導型除草劑草甘膦的競爭性抑制，將epsp合成酶基因轉入植物中可獲得草甘膦耐受植株。In addition to avermectins, s. avermitilis produces oligomycin, a strongly toxic compound. gene deletion vector pxl05 was used to disrupt oligomycin polyketide synthase ( pks ) encoding genes ( olma ) in streptomyces avermitilis cz8 - 73, the producer of anthelmintic avermectins b and the cell growth inhibitor oligomycin. olma gene cluster in the chromosome was displaced by deletion allele on the plasmid via double crossover
本研究以產阿維菌素b和寡黴素的阿維鏈黴菌cz8 - 73為出發菌株，構建了基因缺失載體pxl05 ，並將其轉入cz8 - 73中，通過缺失載體和染色體之間的同源雙交換，對染色體上長達90kb的寡黴素聚酮合酶（ pks ）基因簇（ olma ）進行了缺失。The keti acid is converted to isoleucine by the activity of amino transferases.
酮酸被氨基轉移酶轉變為異亮氨酸。Phenylketonuria is a condition in which phenylalanine to tyrosine conversion is diminished because the enzyme phenylalanine hydroxylaze is deficient.
苯丙酮酸尿癥是一種由於苯丙氨酸羥化酶缺乏，苯丙氨酸轉變成酪氨酸的過程被削弱的病。Phenylketonuria ( pku ) is an inherited metabolic disease that results in mental retardation and other neurological problems when treatment is not started within the first few weeks of life. the disease arises from the deficiency of a single enzyme, phenylalanine hydroxylase, which converts the essential amino acid, phenylalanine, to another amino acid, tyrosine. failure of the conversion to take place results in a buildup of phenylalanine in the body that then damages the central nervous system
苯丙酮尿癥（ pku ）是一種智力發育不全的先天性疾病，患者由於肝贓內苯丙氨酸羥化酶缺乏，苯丙氨酸不能正常代謝為酪氨酸，從而導致苯丙氨酸在肌體組織內積累，引起腦損傷和累進性精神障礙，臨床表現為智力低下，頭發顏色轉黃，尿有異臭味，重者似鼠臭。The amino group becomes attached to the coenzyme to form pyridoxamine phosphate, and is then transferred to the a - keto acid, which is usually pyruvic acid, oxaloacetic acid, or - ketoglutaric acid
反應中氨基首先連接在輔酶上形成磷酸吡哆氨，然後氨基轉移到-酮酸上，這種-酮酸可以為丙酮酸、草酰乙酸或是-酮戊二酸。The 11 - hsd1 expression in the fetal brain also gradually increases with gestational age at late gestation and continues to increase in the hippocampus after birth until the 15th postnatal day, which shows a pattern very similar to th secretion. furthermore, previous data show injection of thyroxine ( t4 ) to normal newborn rats up - regulates gr expression in the hippocampus. these data suggest that the role of th in neural development may be partially ( if not all ) accomplished through regulating gc ' s activity
在海馬結構， 11 - hsd1與gr共存於同一海馬神經元內，主要呈現還原酶的特性，能使無活性的11 -脫氫皮質酮（ a ）可的松（ e ）轉化為有活性的皮質酮（ b ）皮質醇（ f ） ，從而提高組織局部的糖皮質激素濃度，這樣， 11 - hsd1的存在就為親和力較低的gr發揮作用提供了前提條件。Many legume plants may produce the beneficial isoflavones, which are vital to the formation of nitrogen - fixing root - nodules and the disease resistance response of plants. white clover ( trifolium repens ), a high quality legume forage, however, has little isoflavones. to improve the isoflavone contents of such forage, an available strategy is to introduce gene ( s ) encoding the key enzyme ( s ) in the biosynthesis pathway of insoflavones
許多豆科植物中都含有異黃酮類化合物，異黃酮對植物根瘤的形成和植物的防禦反應至關重要，但是在牧草白三葉中缺乏這種有益的化合物，因此通過轉基因實驗將異黃酮合成酶基因導入白三葉中，提高其異黃酮的含量，增加白三葉的營養價值。That shows there are some difference in the steroid regulation between the anuras and the urodeles. among three of the steroid, one can convert to the other, and some enzyme activity is concerned with the conversion
三種類固醇激素存在相互轉化的關系，睪酮可能在雌二醇和孕酮的轉化中起著底物的作用，這種轉化與某種芳香化酶的活性有關。This inactive product is cleaved by a converting enzyme, mainly in the lung but also in the kidney and brain, to an octapeptide, angiotensin ii, which is a potent vasoconstrictor that also stimulates release of aldosterone
這一非活性產物經轉換酶裂解，主要是在肺部但也在腎和腦部，成為八肽，即血管緊張素，這是和中強烈的血管收縮素，可刺激醛固酮的釋放。The a - transglucosidase was selectively modified by pcmb, me, edc, clac, acetyl acetone and nbs, and changes in the activities of the enzyme have been detected. the reaction of a - transglucosidase with pcmb, me, edc and clac resulted in a strong inhibition of the enzyme activities which decreased with the increase of modifier concentration. the acetyl acetone and nbs were found without inhibition effect
酚丙酮、小涅代唬拍酷亞胺剛b引等化學修飾劑對a葡萄糖轉苦酶的幾種氨基酸殘基進行選擇修飾，並測定其酶活力變化，結果表明： pcmb 、 me 、 edc 、 ciac能顯著抑制酶的活性，活力的下降與修飾劑的濃度有關，乙酚丙酮、 nbs白巾飾對酶的奪製作用不明顯。Ppsa and tkta are the key genes in central metabolism of aromatic amino acids biosynthesis. ppsa encoding phosphoenolpyrucate synthetase a ( ppsa ) which catalyzes pyruvate into pep ; tkta encoding transketolase a which plays a major role in erythrose - 4 - phosphate ( e4p ) production of pentose pathway
Ppsa基因編碼磷酸烯醇式丙酮酸合成酶a （ ppsa ） ，該酶催化丙酮酸合成磷酸烯醇式丙酮酸； tkta基因編碼轉酮酶a ，該酶在磷酸戊糖途徑中生成4 -磷酸赤蘚糖起主要作用。An expression vector carrying a fragment encoding the amino - terminal part of an fr - 008 type i pks module, containing a keto - synthase ( ks ) and part of an acetyl - transferase ( at ) domain was constructed for trial expression of the extremely high g + c content ( 76 % ) pks gene in plant
為探索在植物中表達極高g + c含量的pks基因的可能性，構建了攜帶有編碼fr - 008型pks模塊氨基端部分的基因的表達質粒，包括一個酮基合酶（ ks ）和部分酰基轉移酶（ at ）活性結構域。Which may provide the molecular basis for the inberine regulation of ll p - hsdl expression by glucocorticoids. secondiy, the regulation of l l 9 - hsdl expression and redutase activity by glucocorticoids was investigated in the primny cultured human chorionic trophoblast
整個妊娠過程中胎盤11 - hsd活性以氧化酶為主，使母體gc在進入胎兒循環前大部分被轉化為無活性的17 -羥- 11 -脫氫皮質酮，保證胎兒正常發育所需的激素濃度。The rat 20a - hydroxysteroid dehydrogenase ( 20ahsd ) belongs to a family member of aldo - ketoreductases used nadph as a cofactor and principally converts progesterone to 20a - hydroxyprogesterone as a lower or non - active hormone. thus 20ohsd acts as a molecular switch and makes the potent progesterone hormone into an inactive potent metabolite
大鼠20 -羥類固醇脫氫酶（ 20 - hydroxysteroiddehydrogenase ， 20 hsd ）屬于醛酮氧化還原酶系成員，在大鼠卵巢中以nadph為輔酶將孕酮轉變為低或無活性的20 -羥孕酮。In order to establish the genetic transformation system of saussurea medusa maxism by agrobacterium rhizogenes, some work were done. the main results were following : 1 establishment of regeneration systems two systems of regeneration from saussurea medusa maxim were established without cold treatment. the somatic embryos were induced from callus cultured in mise for 35 days. the shoots were induced from cotyledon after cultured in misc 20 days, and from leave which were cultured in misl. the experiment showed that the carbon and glycine in the medium could help to increase the regeneration rate to 95 %
為篩選水母雪蓮代謝突變體和轉基因研究奠定了一定的基礎，陳亞瓊： m質粒介導水母雪蓮的遺傳轉化及毛狀根中決刪合成的調節p義摘要也為研究類黃酮代謝途徑的關鍵酶基因的轉化、高效表達及作用機理提供了理想的實驗體系。主要的實驗結果如下： 1水母雪蓮高頻再生體系的建立通過體細胞胚胎發生途徑和器官發生途徑，水母雪蓮（ squssureamedusamaxim ）可以在常溫下獲得再生植株。It presented a natural target because aromatase converts testosterone into estradiol, a potent form of estrogen also used in hormone replacement therapy
由於芳香酶能把睪酮轉化為雌二醇，而雌二醇也是一種能用於激素替代療法的雌激素，它就提供了一個天然的靶點。Finasteride, an inhibitor of 5alpha - reductase, inhibits the conversion of testosterone to dihydrotestosterone, the primary androgen in the prostate, and may reduce the risk of prostate cancer
作為一種5 -還原酶的抑制劑，非那斯提可以阻止睪酮轉化為雙氫睪酮（前列腺內最主要的雄激素） ，所以可能會降低前列腺癌的發病率。分享友人