連環蛋白 的英文怎麼說

中文拼音 [liánhuándànbái]
連環蛋白 英文
catenin
  • 連 : Ⅰ動詞1 （連接） link; join; connect 2 （連累） involve （in trouble）; implicate 3 [方言] （縫） ...
  • 環 : Ⅰ名詞1 （環子） ring; hoop 2 （環節） link 3 （姓氏） a surname Ⅱ動詞（圍繞） surround; encircle;...
  • 蛋 : 名詞1. （鳥類或龜、蛇類所產的卵） egg 2. （像蛋形的東西） an egg-shaped thing 3. （辱罵之詞）
  • 白 : Ⅰ形容詞1 （似雪的顏色） white 2 （清楚; 明白; 弄明白） clear 3 （空的; 沒加他物的） pure; clear; ...
  • 連環 : chain of rings; interlink; connecting ring連環分子 catenated molecule; 連環畫 a book with a story...
  • 蛋白 : 1. （卵中透明的膠狀物質） egg white; albumen; gary2. [生物化學] （蛋白質） protein
  1. Changes in p - catenin expression or localization were found in cancer cells and tumor tissues, it had been reported that p - catenin translocated from membrane at the normal condition into the cytosol or nucleus in cancer cells. recently, p - catenin has been referred to an oncogene

    研究發現，癌變的細胞中-連環蛋白的分佈發生了異常，由胞膜轉移到胞漿和胞核，因此，已把-連環蛋白歸為一個新的癌基因。
  2. Construction, expression and cell growth inhibition of translocating peptide granzyme b fusion protein gene

    連環蛋白基因功能區截短突變體的構建及其功能
  3. Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues, and in this situation, the ccc has been disrupted and cell adhesion function disturbed. a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc, and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription

    當-連環蛋白酪氨酸或絲氨酸殘基磷酸化后，就與ajs發生解離而游離到細胞漿中，此時細胞的粘附功能也發生障礙，游離到胞漿中的-連環蛋白，一部分被抑癌因子apc降解，一部分則轉移到細胞核內，與核內的轉錄因子tcf lef結合，啟動與細胞增殖有關的基因轉錄。
  4. There is a relationship between catenin phosphorylation, translocation and tumoregenesis, further more, in this relationship, cell signaling cascade and mitogen and their receptors are involved. base on these evidences, people are trying to disturb the key molecules in this signaling cascade for anti - tumor purpose

    表皮生長因子（ egf ）能使p120 ~ （ ctn ）酪氨酸磷酸化，磷酸化使bel - 7404細胞的粘附能力降低而遷移行為增強； p120 ~ （ ctn ）在細胞內的分佈出現明顯的核內轉位， -連環蛋白也出現相似的變化。
  5. Catenin binds to the cytoplasmic tail of a transmembrane cell adhesion molecule - epithelial cadherin ( e - cadherin ) in epithelial cells and forms an adhesion complex [ e - cadherin - p - catenin ( or y - catenin ) - cc - catenin ] ( cadherin - catenin - complex, ccc ), this complex play an important role in maintaining epithelial cell adhesion. some catenins such as -, - and p120ctn catenins are also crucial in cell signaling, they play an important role in cell proliferation and cell apoptosis

    在上皮細胞內，連環蛋白均能與跨膜細胞粘附分子?上皮鈣粘蛋白（ e - cadherin ）的胞內肽段結合而形成了由上皮鈣粘蛋白- -連環蛋白（ -連環蛋白） - -連環蛋白組成的粘附連接體（ adherensjunctions ， ajs ） ，這種復合體對維持細胞正常的粘附功能是必需的。
  6. By studying mice with fractures the researchers were able to show that - catenin - mediated gene transcription was actiated in both bone and cartilage formation during fracture repair

    通過研究骨折小鼠，研究小組發現在骨折修復過程中，硬骨和軟骨中由連環蛋白介導的基因轉錄都是激活的。
  7. By studying mice with fractures the researchers were able to show that - catenin - mediated gene transcription was activated in both bone and cartilage formation during fracture repair

    通過研究骨折小鼠，研究小組發現在骨折修復過程中，硬骨和軟骨中由連環蛋白介導的基因轉錄都是激活的。
  8. Cell adhesion to surface of the substrate is essential to development of the anchorage - dependent cells. only after adhering to surface followed by spreading can cells develop and proliferate. most synthetic polymers used as orthopaedic matrix substitute present hydrophobicity, which may correlates to the low degree of cell attachment. modification with cell adhesion protein / peptides can be benificial to the cell adhesion on polymers and then affect the cell proliferation and differentiation. cell attachment to substrate is primarily mediated by integrins, a widely expressed family of heterodimeric surface receptors. most extrcellular matrix proteins such as fibronectin, osteopontin, collagen type i, bone sialoprotein and vitronectin contain an arg - gly - asp ( rgd ) sequence which is specific to the fixation of cell membrane receptors like integrin. the main aim of this research is to measure, assess adhesion, proliferation of rabbit marrow stromal cells ( mscs ) on the polymers coated by fibronectin, collagen type i or biotie gen, which includes : ( 1 ) biologic characteristics of rabbit mscs were observed by two types of separating method in primary culture. ( 2 ) adhesion, proliferation and differentiation of mscs cultured on polymers coated with biotiegen were assessed. ( 3 ) also, adhesion, proliferation and differentiation of mscs were assessed on plga film or porous plga substrates coated with fibronectin, or collagen type i respectively. ( 4 ) bone formation was observed on the porous plga substrates coated with collagen type i in vivo. this research aims to give new way to make novel synthetic bone with cell adhesion and high bone induction capabilities

    因此將這些蛋白包被、固定到材料表面，觀察骨組織工程種子細胞mscs細胞的粘附、生長特性是本研究的中心環節，並從以下方面進行探討： （ 1 ）採用不同原代細胞分離方法，研究其對mscs細胞的生物學特性影響。 （ 2 ）檢測基因勝肽膠對mscs細胞粘附、增殖及分化的影響。 （ 3 ）分別採用型膠原及纖維粘連蛋白（ fibronectin ， fn ）包被聚乙醇酸-乳酸共聚物（ poly （ 1actide - co - glycolide ） ， plga ）膜及多孔塊型plga材料，觀察細胞在單層或三維培養狀態下，型膠原及fn對mscs細胞粘附、增殖及向成骨細胞分化效應及能力。
  9. The effect of - catenin on the mechanism of intestinal stem cell proliferation and differentiation

    連環蛋白與腸幹細胞增殖分化機制
  10. In mice that lacked - catenin fracture healing was inhibited, whereas in mice expressing an actiated form of - catenin bone healing was accelerated

    缺乏連環蛋白的小鼠其骨折愈合是遲緩的，而連環蛋白表達活躍的小鼠的骨折愈合是加快的。
  11. In mice that lacked - catenin fracture healing was inhibited, whereas in mice expressing an activated form of - catenin bone healing was accelerated

    缺乏連環蛋白的小鼠其骨折愈合是遲緩的，而連環蛋白表達活躍的小鼠的骨折愈合是加快的。
  12. P120ctn is a more newly found catenin, studies revealed that it is also an important molecule in e - cadherin mediated cell - cell adhesion, and phosphorylated tyrosine in p120ctn were evidenced. translocation of p120ctn occurred in cancer cells and tissues. evidences showed that there were a key relationship between p120ctn translocation and tumoregenesis

    P120 ~ （ ctn ）是發現得較晚的一種連環蛋白，研究發現它也參與上皮鈣粘蛋白介導的細胞粘附過程並且不可缺少，同時p120 ~ （ ctn ）也和-連環蛋白一樣易於酪氨酸殘基磷酸化，磷酸化后的p120 ~ （ ctn ）也發生轉位，並與腫瘤的發生發展有密切關系。
  13. His research work mainly concerns microcirculation, shock, fibronectin, tumor necrosis factor, dysfunction of microvascular endothelial cells and mechanism of weight - reducing. more than 200 scientific papers were published in domestic or abroad journals

    近年來主要從事微循環、休克、纖維連接蛋白、腫瘤壞死因子、血管內皮細胞功能障礙及減肥機制等方面的研究，在國內外雜志上發表論文200餘篇。
  14. 1. the relationship between protein kinase c and remember behavior alteration of mice exposed to lead. introduction lead has high affinity to nerve and it can be accumulated in nerve tissues, which can cause long - period damage to nervous system, especially to memory and learning function

    一、慢性鉛暴露小鼠腦組織蛋白激酶c活性變化及其與記憶行為改變的關系前言學習記憶是腦的高級功能，其物質基礎是中樞神經系統高度的可塑性，包括神經網路、神經環路及突觸連接等不同水平的可塑性。
  15. Also we found that p120ctn expressed mainly at cell membrane at cell - cell contact region in lo2 imortal human liver cells, while the molecule expressed mainly in cytoplasm and in nucleus in bel - 7404 human liver cancer cells, membrane expression reduced or disappeared in these cells. the molecule expressed at membrane, no immunoreaction was detected in cytoplasm or in nucleus in normal liver tissues

    而p一連環蛋白則變為胞核表達減少，胞漿和胞膜表達增加的有趣現象，提示p120cin在細胞粘附過程中是必需的，而且在信號轉導過程中它與p一連環蛋白可能存在某種競爭現象或其他聯系，有待進一步研究。
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