骨骼缺陷 的英文怎麼說
中文拼音 [gǔgéquēxiàn]
骨骼缺陷
英文
skeletal defect- 骨 : 骨名詞1 (骨頭) bone2 (物體內部的支架) framework; skeleton 3 (品質; 氣概) character; spirit ...
- 缺 : Ⅰ動詞1 (缺乏; 短少) be short of; lack 2 (殘缺) be missing; be incomplete 3 (該到而未到) be ...
- 陷 : Ⅰ名詞1 (陷阱) pitfall; trap2 (缺點) defect; deficiency Ⅱ動詞1 (掉進) get stuck or bogged do...
- 骨骼 : skeleton; ossature
- 缺陷 : defect; fault; faultiness; vitium; lesion; flaw; disorder; imperfection; drawback; blemish
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The protein nucleic acid complexes were identified by autoradiography for 48 h. the psg5heo and igfbp - 6 promoter pcat vectors were transfected into cos - 7 cells with iipofectamin2000 ; these cos - 7 cells where treated with 1 jxm e2, with lonm tcdd and with both lonm tcdd and 1 jxm e2, individually ; the cat protein was examined by cat - els a. results : the congenital skeletal defects in fetal rats were induced with 10 - 15ug / kg tcdd or with 100 - 140 mg / kg ra with dosage - dependence effect. the igfbp - 6 mrna in rat calvaria tissue and mc - 3t3 - el cells were increased with tcdd and ( or ) ra, whereas the cell proliferation and igf - 2 mrna in mc - 3t3 - el cells was decreased in the status of e2
結果: tcdd在大鼠胚胎發育時期具有骨骼致畸作用,骨骼發育畸形包括:內翻足、脊柱裂、顱面骨發育缺陷、無尾畸形等;隨著tcdd濃度的升高( 10一15林擴kg ) ,致畸率明顯上升( 14 . 7 %一24 . 6 % ) ; tcdd和ra聯合用藥可以增強對大鼠骨骼發育的致畸效應; e :對成骨細胞內igf一2基因有正性調節作用,對igfbp一6基因有負性調節作用, tcdd可以抑制e :對細胞內xgf一2和igfbp一6的調節作用。All grades of disorders occur, ranging from defective skeletal coverings to absence of the brain.
所有發生紊亂的程度,從有缺陷的骨骼外殼到缺腦不等。
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