carcinogenesis 中文意思是什麼

From different points of view of the epidemiology, cytogenetics, molecular biology, experimental pathology and preventive medicine, this study revealed and proved that the genotoxicity and carcinogenesis existed in the drinking pond water in the high incidence area of live cancer in guangxi, indicated the feasible preventive and interruptive methods, too

從分析流行病學，細胞遺傳毒理學、分子生物學、實驗病理學和預防醫學的不同角度，揭示和論證了廣西某肝癌高發區居民飲用塘水的基因毒性和致癌性，提出了切實可行的預防和阻斷措施。

Monofunctional alkylating agent n - methyl - n ' - nitro - n - nitrosoguanidine ( mnng ) is a widely spread environmental mutagen and carcinogen that targets dna and proteins to generate adducts. among the adducts, o6 - alkyl guanine is the predominant mutagenic lesion because of its mispairing properties, which can eventually lead to chromosomal aberrations, point mutations, and cell death. this lesion also appears to be involved in tumor initiation, particularly in gastric carcinogenesis

單功能烷化劑n -甲基- n -硝基- n -亞硝基胍（ mnng ）是一種在環境中廣泛存在的化學誘變劑和致癌劑，它能和dna及蛋白質等生物大分子形成加合物（ adduct ） ，其引起的與突變有關的主要dna損傷類型是o ~ 6 -甲基鳥嘌呤，這種損傷與腫瘤尤其是胃癌的發生密切相關。

Screening of the carcinogenesis associated gene in gastric mucosa by gene chip

用基因晶元篩選胃黏膜癌變相關基因

Advancement of studying the biological characteristics of nasopharyngeal carcinogenesis

鼻咽癌變過程生物學特性研究的進展

Chromosomal instability is associated with a primary event or a subsequent event during cancer development. therefore, to understand how arsenic induces chromosome instability may be of fundamental importance to further characterize mechanisms of carcinogenesis

由於染色體不穩定性與癌癥發生的早期事件和晚期變異均有密切的關連，因此探討砷化物誘引染色體不穩定性的機制，將可應用於了解癌癥發生的機制。

Animal experiments showed that the concentrates of whey proteins also exhibit anti - carcinogenesis and anticancer activity

動物實驗的結果顯示：怡妙康還具有抗致癌作用和抗腫瘤的活性。

Background regular use of aspirin reduces the risk of a colorectal neoplasm, but the mechanism by which aspirin affects carcinogenesis in the colon is not well understood

研究背景：定期服用阿斯匹林降低結直腸癌的風險，但是阿斯匹林影響腸道致癌作用的機制並不是很清楚。

Chemical carcinogenesis in culture has proved to be a much more difficult field of investigation than viral carcinogenesis.

在培養內化學致癌已證明是一個比致癌困難得多的研究領域。

Multistep nature of carcinogenesis proven

證明癌形成是多階段的特點

Effects of boschniakia rossica extract on the serum antioxidative activities and tumor necrosis factor in initial stage of rat chemical hepato - carcinogenesis in rats

草蓯蓉提取物對大鼠肝癌前病變模型血清抗氧化酶活性及腫瘤壞死因子的影響

It is a new strategy to explore the mechanism of tumor carcinogenesis, and to regulate the network, key molecules, and drug target by combined biology effects

用綜合生物學效應來闡明疾病發生發展機制、相關調控網路、關鍵靶分子和藥物靶點，為腫瘤的診斷、分型、藥物研製提供新思路。

Among the biological effects, radiation carcinogenesis is the most worrying problem

摘要在游離輻射的生物效應中，最為大眾所疑慮的當屬輻射的致癌效應。

In order to further investigate the role of axudl in human tumor carcinogenesis and the potential association between the axudl gene expression status and the stimulation of transforming growth factor beta in human cancers, the present study was performed in three aspects as follows : ( 1 ) cloning full length enconding region cdna of axudl and construction of eukaryotic vector that expression the fusion protein of axud1 and influenza virus hemagglutin ha epitope tag ; ( 2 ) exploring the time and dose effects of tgf - 1 on the expression - of axudl gene in hepg2 hepatoma cells and spc - a1 lung carcinomas cells, and studying the effects of overexpression of axud1 on the expression of cell cycle and apoptosis related protein in hepg2 hepatoma cells ; ( 3 ) construction and expression of human axudl in e. coli m15. the following main results and conclusions can be obtained from the present study : 1. the full length ecnoding region of human axudl cdna from human peripheral blood lymphocytes was successfully cloned using one step rt - pcr method, and constructed into a eukaryotic expression vector which can be expressed a ha - axud1 fusion protein with axud1 and influenza virus hemagglutin ha epitope tag. the recombinant plasmid was identified by polymerase chain reaction, restriction endonuclease maping and sequencing, this expression vector might be instrumental to further study the function of axud1 protein in tumor cells

為了進一步研究axud1在人類腫瘤發生中的作用及axud1基因的表達狀況與tgf -介導的信號通路的關系，本實驗研究分為三個部分： （ 1 ） axud1基因cdna全長編碼區的克隆和ha表位標記的axud1基因表達載體的構建； （ 2 ）探討肝癌細胞hepg2和肺腺癌spc - a1細胞中tgf - 1誘導的axud1基因表達的時間、劑量效應以及誘導表達的可能機理，並研究axud1的過表達對細胞周期和細胞凋亡相關蛋白表達的影響； （ 3 ） axud1原核表達載體的構建及其在大腸桿菌中的表達。本實驗的主要結果和結論如下： 1利用一步法rt - pcr成功地從人類外周血淋巴細胞中克隆出axud1基因編碼區cdna ，並將其構建入真核表達載體中，編碼的ha - axud1融合蛋白帶有流感病毒凝血素ha的表位標記肽段。

Objective ： to detect the telomerase activity in human esophageal carcinoma and tumor ? adjacent tissues and investigate the possible molecular mechanism of esophageal carcinogenesis

目的：檢測食管癌及周圍非癌食管粘膜組織中端粒酶活性，了解食管癌發生可能的分子生物學基礎。

Study on the biomarkers in dmba - induced oral carcinogenesis in hamster

誘發的地鼠口腔癌模型中生物標志物研究

Telomerase is a celler reverse transcriptase which catalyzes the synthesis and extension of telomeric dna. telomerase activation is not observed in normal tissues of somatic origin but in almost 90 % of human cancer, with the result the telomere shorten progressively with cell division and thus is a critical step for multistep carcinogenesis

正常人體細胞（非生殖細胞）中端粒酶活性的表達很低，或用目前的方法幾乎檢測不到，而在90以上的惡性腫瘤中可檢測到端粒酶活性，相應的良性腫瘤則為陰性或僅有少數陽性。

An extension of these ideas is embodied in the theory of allison concerning carcinogenesis.

在阿利森的癌癥發生學說中，這些概念得到發揮。

The expression and significance of interleukin 6 and interleukin 6 receptor in human gastric carcinogenesis

在胃癌發生發展中的表達及意義

The research progress on the relationship between helicobacter pylori infection and gastric mucosa carcinogenesis

幽門螺桿菌感染與胃粘膜癌變關系的研究進展

Chemical carcinogens can cause modifications or damages on dna directly. if these damages are not repaired properly, they result in mutagenesis and carcinogenesis

化學致癌物能直接在dna上造成修飾和損傷：如果沒有被正確修復，這些損傷將導致突變的形成。