catenin 中文意思是什麼

catenin 解釋
連環蛋白
  1. Changes in p - catenin expression or localization were found in cancer cells and tumor tissues, it had been reported that p - catenin translocated from membrane at the normal condition into the cytosol or nucleus in cancer cells. recently, p - catenin has been referred to an oncogene

    研究發現，癌變的細胞中-連環蛋白的分佈發生了異常，由胞膜轉移到胞漿和胞核，因此，已把-連環蛋白歸為一個新的癌基因。
  2. P120ctn weakly expressed or disappeared at membrane in hepatocellular carcinoma tissues, immunoreaction were detected in cytosol and nucleus, it suggested that the molecule had translocated and cells lost adhesion abilities had malfunction in signaling, also p - catenin had similar changes as p120ctn

    20林mol . l一，的芒果貳能幹擾bel一7404細胞周期，使細胞阻止於q一m ，同時有誘導細胞凋亡的作用，其作用於48小時時就很明顯。
  3. Clinical significance of e - cadherin and - catenin expression in colorectal cancer

    鈣黏素表達及其臨床意義
  4. Expression of - catenin and e - cadherin and their significance in colorectal carcinoma

    連環素和上皮鈣粘附素的表達及意義
  5. Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues, and in this situation, the ccc has been disrupted and cell adhesion function disturbed. a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc, and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription

    當-連環蛋白酪氨酸或絲氨酸殘基磷酸化后，就與ajs發生解離而游離到細胞漿中，此時細胞的粘附功能也發生障礙，游離到胞漿中的-連環蛋白，一部分被抑癌因子apc降解，一部分則轉移到細胞核內，與核內的轉錄因子tcf lef結合，啟動與細胞增殖有關的基因轉錄。
  6. There is a relationship between catenin phosphorylation, translocation and tumoregenesis, further more, in this relationship, cell signaling cascade and mitogen and their receptors are involved. base on these evidences, people are trying to disturb the key molecules in this signaling cascade for anti - tumor purpose

    表皮生長因子（ egf ）能使p120 ~ （ ctn ）酪氨酸磷酸化，磷酸化使bel - 7404細胞的粘附能力降低而遷移行為增強； p120 ~ （ ctn ）在細胞內的分佈出現明顯的核內轉位， -連環蛋白也出現相似的變化。
  7. Catenin binds to the cytoplasmic tail of a transmembrane cell adhesion molecule - epithelial cadherin ( e - cadherin ) in epithelial cells and forms an adhesion complex [ e - cadherin - p - catenin ( or y - catenin ) - cc - catenin ] ( cadherin - catenin - complex, ccc ), this complex play an important role in maintaining epithelial cell adhesion. some catenins such as -, - and p120ctn catenins are also crucial in cell signaling, they play an important role in cell proliferation and cell apoptosis

    在上皮細胞內，連環蛋白均能與跨膜細胞粘附分子?上皮鈣粘蛋白（ e - cadherin ）的胞內肽段結合而形成了由上皮鈣粘蛋白- -連環蛋白（ -連環蛋白） - -連環蛋白組成的粘附連接體（ adherensjunctions ， ajs ） ，這種復合體對維持細胞正常的粘附功能是必需的。
  8. By studying mice with fractures the researchers were able to show that - catenin - mediated gene transcription was actiated in both bone and cartilage formation during fracture repair

    通過研究骨折小鼠，研究小組發現在骨折修復過程中，硬骨和軟骨中由連環蛋白介導的基因轉錄都是激活的。
  9. By studying mice with fractures the researchers were able to show that - catenin - mediated gene transcription was activated in both bone and cartilage formation during fracture repair

    通過研究骨折小鼠，研究小組發現在骨折修復過程中，硬骨和軟骨中由連環蛋白介導的基因轉錄都是激活的。
  10. The effect of - catenin on the mechanism of intestinal stem cell proliferation and differentiation

    連環蛋白與腸幹細胞增殖分化機制
  11. In mice that lacked - catenin fracture healing was inhibited, whereas in mice expressing an actiated form of - catenin bone healing was accelerated

    缺乏連環蛋白的小鼠其骨折愈合是遲緩的，而連環蛋白表達活躍的小鼠的骨折愈合是加快的。
  12. In mice that lacked - catenin fracture healing was inhibited, whereas in mice expressing an activated form of - catenin bone healing was accelerated

    缺乏連環蛋白的小鼠其骨折愈合是遲緩的，而連環蛋白表達活躍的小鼠的骨折愈合是加快的。
  13. Detection of urinary mcp - 1, - catenin and ck19 molecules in patients with renal diseases and their correlations with crescents in glomeruli

    腎臟病患者尿液中三種分子的檢測及其與腎小球新月體病變的關系
  14. P120ctn is a more newly found catenin, studies revealed that it is also an important molecule in e - cadherin mediated cell - cell adhesion, and phosphorylated tyrosine in p120ctn were evidenced. translocation of p120ctn occurred in cancer cells and tissues. evidences showed that there were a key relationship between p120ctn translocation and tumoregenesis

    P120 ~ （ ctn ）是發現得較晚的一種連環蛋白，研究發現它也參與上皮鈣粘蛋白介導的細胞粘附過程並且不可缺少，同時p120 ~ （ ctn ）也和-連環蛋白一樣易於酪氨酸殘基磷酸化，磷酸化后的p120 ~ （ ctn ）也發生轉位，並與腫瘤的發生發展有密切關系。
  15. Aes contains a glutamine - rich ( q ) domain in its n - terminal, which sharing high homology with the amino terminal region of groucho / tle ( transducin like enhancer of split ). the function of aes is not clear yet, while groucho / tle were found to be a family of transcription co - repressor and play impo rtant roles in notch signaling, wnt - 0 catenin signaling and other transcription regulation events

    Aes的n -末端約130個氨基酸中富含谷氨酰眩（ q ）殘基，形成一個q結構域，與轉錄協同抑制分子tle （ transducinlikeenhancerofsplit ）的氨基端高度同源。
  16. Construction and functional study of truncated catenin genes

    7細胞中的表達
  17. Relationship between the expression of - catenin and the invasion and metastasis of colorectal carcinoma

    在結直腸癌中的表達及其意義
分享友人
分享到 Line

分享到臉書