cellular localization 中文意思是什麼

cellular localization 解釋
細胞定位
  • cellular : adj. 1. 【生物學】細胞的，細胞質[狀]的。2. 【建築】區劃[分格]式的；小室的。3. 多孔的；有窩的。4. ＝cellular phone.
  • localization : n. 1. 定位，定域。2. 局限。3. 地方化。
  1. We fused the gfp into the c - terminal region as well as n - terminal region of emt - 1 protein. the result showed that the localization of the protein encoded by the full length emt - 1 cdna was in endoplastic reticulum ( er ). extracellular region, transmembrane and intracellular region showed the similar cellular localization

    我們用綠色熒光蛋白融合於emt l全長及其不同截斷形式的梭基和氨基端，瞬時轉染cos 7細胞，通過熒光顯微鏡觀察，發現emt l編碼的蛋白呈現內質網定位的特點。
  2. Wireless localization and tracking is a hot research topic, several theorestic and applied results have been in recent years. this paper addressed two problems : 1. how to mitigate position error caused by non - line - of - sight ( nlos ) propogation when we use range - based tracking algorithm in cellular networks

    本文探討了其中的兩個問題: 1 .在跟蹤蜂窩移動通信網路中移動終端的運動軌跡時，如何利用粒子濾波器減弱非直達波傳播對濾波跟蹤演算法精度的顯著影響
  3. The cellular localization of hse was done by using in situ hybridization, the results showed that primary spermtatocytes and spermatids in seminiferous tubular have positive signals. the subcellular localizations of hsei and hseii were identified by gfp fusion protein. hsei - gfp fusion protein was evenly distributing in cytoplasm, while hseii - gfp was not evenly distributing in cytoplasm and there were many bright spots in cytosol

    用gfp高合蛋白的技術確定hsei和hsell在細胞中勺定位，結果顯示hsei gfp均勻地分佈於細胞漿中，而hsell0fp則分佈不均勻，在胞漿有聚集成許多熒光信號很強的點。
  4. In this study, we showed that the pdk inhibitor ly294002 regulated the cellular localization of materials 1. kunming mice were supplied from the department of laboratory animals, china medical university 2. pregnant mare serum gonadotropin ( pmsg ) and human chorionic gona - dotropin ( hcg ) were obtained from tianjin huafu biological products research institute and shanghai products research insititute, respectively

    為了研究在小鼠受精卵中pkc 、 pkb是否也通過p21蛋白參與調控g2 m轉換，本實驗應用了pma和ly294002作為pkc 、 pkb的抑制劑，研究它們對小鼠受精卵中p21蛋白表達和定位，進一步探討可能的調控機制。
  5. The cellular localization of kvl. 2 and the co - localization of kvl. 2 and vegf receptors in the rat brain in rat cerebral cortex, triple - fluorescence labeling for kvl. 2, nse, and gfap showed that kvl. 2 immunopositive labeling was predominantly seen on the membrane of the cells co - stained with nse, a specific neuronal marker. only few kvl. 2 positive labeling cells were co - stained with gfap, an astrocyte glial cell marker

    大鼠腦內kv1 . 2蛋白的細胞定位及其與vegf受體間的共存關系大鼠大腦皮層kv1 . 2 、 nse 、 gfap免疫熒光三標結果： kv1 . 2蛋白分佈在細胞膜上，大部分kv1 . 2免疫陽性細胞表達有nse ，只有在少量kv1 . 2陽性細胞上表達有gfap 。
  6. To make clear the hypothesis, a middle cerebral artery occlusion ( mcao ) and hypoxia and glucose - deprivation ( hgd ) ischemic models were used in in vivo and in vitro study, respectively. we first studied the cellular localization of kvl. 2 and the co - localization of kvl. 2 protein and vegf receptors flk - 1 and flt - 1, observed the effect of mcao on kvl. 2 expression and phosphrylation in the rat brain in vivo, then investigated the effect of vegf on ischemia / hypoxia cell damage and tyrosine phosphorylation of kvl. 2 in sh - sy5y cells. finally, in order to further elucidate the relationship between vegf ' s neuroprotection and its regulation on kvl. 2 phosphorylation, we used a specific antisense oligodeoxynucleotide ( odn ) to knockdown the expression of endogenous vegf to observe its role in ischemia / hypoxia cell damage and regulation of kvl. 2 phosphorylation

    為了驗證上述假設，本文分別在整體和離體水平，採用大腦中動脈缺血（ middlecerebralarteryocclusion ， mcao ）和體外氧?糖剝奪（ hypoxiaandglucose - deprivation ， hgd ）缺血模型，首先了解了kv1 . 2蛋白的細胞定位及與vegf受體flk - 1和flt - 1的共存情況，觀察了整體mcao后缺血再灌不同時間大鼠腦內kv1 . 2蛋白的磷酸化水平變化，然後通過外源性給予vegf蛋白，在sh - sy5y細胞株上觀察其對缺血細胞存活率及kv1 . 2蛋白磷酸化水平的影響，最後利用vegf反義脫氧寡核苷酸（ oligodeoxynucleotide ， odn ）特異阻斷內源性vegf蛋白的表達，觀察內源性vegf蛋白在缺血細胞損傷及調節kv1 . 2蛋白磷酸化中的作用，以進一步明確vegf缺血保護效應與其調節kv1 . 2蛋白磷酸化之間的關系。
  7. This article mainly discusses the challenges, research approaches and recent developed tools in the field of protein function prediction and the ways by which these issues change the process of drug discovery, including homology - based annotation transfer, sequence motifs and patterns, information on 3d structure, sub - cellular localization, posttranslational modifications, binding sites and functional residues, protein - protein interactions

    摘要簡述了在蛋白質功能預測領域中的研究方法和最新研發工具所面臨的挑戰，並討論蛋白質功能預測是如何改變藥物開發進展的，具體包括：基於序列同源性分析的注釋轉移、序列基元和模式增加了注釋轉移的說服力、 3d結構信息可以精煉注釋轉移、亞細胞定位、翻譯后修飾、結合位點和功能殘基、蛋白質之間的相互作用。
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