dominant negative 中文意思是什麼
dominant negative
解釋
癌基因的顯性負作用-
Interestingly, inhibition of p38 mapk activation ( but not erk activation ) by its inhibitors or by expression of a dominant negative mutant of p38 mapk could effectively block the chemotactic effect of ( - arrestin2
P38mapk上游激酶ask1的顯性失活突變體也可以阻斷- arrestin2對趨化的增強作用。這說明是p38mapk而不是erk信號通路與- arrestin2對趨化的增強作用相關。 -
The lowest species diversity occurs in the community iv in which microlepia sino - strigosa ching is the dominant species, while the highest species diversity occurs in the community i. in the communities studied, the total related differences vr are from 7. 19 to 4. 95, and the test statistics w are from 229. 96 to 49. 95, which indicates a notable positive correlation among species which have consanguineous relationships each other in the communities and the communities are in a fairy stable period. from the test of the interspecific relatedness among species in the communities we know that s. tsinyunensis present negative correlations with all the concomitance species, among which there are 8 species pairs of notably negative correlation and 51 species pairs of extremely notable negative correlation
4 ）群落主要物種間聯結性檢驗中，對各個群落調查的物種和種對依次為（從群落） ： 20種44對、 11種38對、 16種42對、 13種16對、 11種26對、 14種51對、 14種20對、 17種51對，其中縉雲黃芩與群落中其主要伴生物種間全部表現為負聯結，其中有9個種對間聯結性達到顯著水平，有50個種對間聯結性達到極顯著水平。 -
3 ) foa ( fluoroorotic acid ) treatment with the dominant negative mutants showed that the dominant negative effects of mutants were caused by the presence of the gpi17 vector, not by another mutation located somewhere in the genome and in a gene involved in the natural resistance against copper
3 ） foa （ 5 -氟-乳清酸）處理突變體細胞表明，得到的顯性負性突變體不是細胞中銅抗性基因突變的產物，其確為gpi17突變引起。 -
Agrin inhibits rac activity in developing neurons and expression of dominant negative rac1 abolishes agrin - induced growth cone turning and substantially inhibits neurite extension
我們的實驗也表明， agrin抑制發育中神經元rac的活性。 dn - rac1的表達完全阻斷了agrin引起的生長錐導向，並抑制突起的生長。 -
Expression of either dominant negative or antisense musk in cultured xenopus laveis spinal neurons abolishes agrin - induced neurite outgrowth inhibition and converts chemorepulsive growth cone turning induced by a gradient of agrin into chemoattraction
Musk突變體（ dm - musk ）或反義musk （ as - musk ）的表達，解除了agrin對新生突起生長的抑制，並且把agrin誘導的排斥反應反轉為吸引反應； musk介導發育中神經元突起的生長。 -
2 ) the growth curves for different cells show that overexpression of gpil7p has no lethal effect on the yeast cells and only that of the dominant negative mutants can cause cells not grow
2 ）生長曲線的測定表明，過表達gpi17p對正常酵母細胞不致死，而只有顯性負性突變體的過表達才會導致酵母細胞不能生長。 -
Dominant negative alleles of gpil7p were produced by random pcr mutagenesis of three conserved fragments of gpi17p : 1 ) having generated the plasmid library which contains 100000 plasmids harboring gpi17 mutants then screened from 8000 clones, we got 25 strong and 3 very strong dominant negative alleles
對gpi17p可能的三個保守區進行了pcr隨機誘變，並最終獲得顯性負性等位基因： 1 ）組建了gpi17p突變體質粒庫，其所含質粒數約為100000 。 -
Twenty f1 combinations crossed among 5 varieties and strains different in fiber properties according to complete diallel crossing design were used to evaluate the heterosis and gene action of boll weight and lint percentage in high quality fiber property varieties in upland cotton in 1998 1999 for two year successively at nanjing. it was indicated that there existed small interactions with the environmental factors without maternal effects and the additive gene effect was in chief, attaining to 51. 2 % and 65. 4 % respectively for boll weight and lint percentage. the dominant effect was also in higher rate, 32. 6 % and 16. 8 % respectively. the population mean heterosis of boll weight and lint percentage over the mid - parental mean were relatively prominent 13. 3 % and 3. 5 % respectively in extreme significance. however, boll weight showed no significantly surpassing parental f1 heterosis over the better parent based on population mean ( 2. 0 % ) ; while the lint percentage expressed significant negative heterosis value ( - 2. 1 % ). the gene actions were in conformity with the heterosis expression. it was shown clearly that the f1 combinations crossed between parents with similar performances had relatively high dominant effects and significant positive f1 surpassing parental heterosis ( f1 heterosis over the better parent ) ; while no f1 combination crossed between the parents with prominent mutual difference surpassed the higher parent in yield components, which indicated that among those parents with less difference and close relationships, there still existed sufficient genetic variation or certain mechanism for creating variation and achieving greater advances in breeding. correlation analyses also indicated that there still existed severely undesirable negative correlation between yield and fiber properties as well as the difficulties for their simultaneous improvements
利用5個具有不同纖維品質性狀的品種（系）配製完全雙列雜交組合20個，通過親本和f1的2年隨機區組試驗發現產量性狀的鈴重和衣分與環境的互作效應小，不存在母體效應，並以加性遺傳效應為主，分別占表型方差的51 . 2 %和65 . 4 % ;顯性遺傳效應所佔的比率也較高，分別為32 . 6 %和16 . 8 % .鈴重和衣分的群體平均優勢較大，分別為13 . 3 %和3 . 5 % ，達到了極顯著;鈴重的超親優勢為2 . 0 % ，不顯著;衣分為顯著的負值（ - 2 . 1 % ） .遺傳分析與雜種優勢結果一致.具體表現在產量性狀上，親本相當配製的組合雜合顯性較高，其超親優勢正向顯著，而極值親本（差異較大）所配組合沒有超過高親的.這表明親本差異小、親源關系較近的親本中仍然存在足夠的遺傳變異或某種機制以創造變異使育種取得更大的進展.相關分析表明了仍然存在嚴重的品質與產量的負相關，遺傳改良的難度較大 -
There are certain relations between circulation pattern index ' s decadal variance characteristic and decadal variation tendency of the precipitation of china : in the 1960s and the 1970s, in which the negative index are relatively more, the precipitation are abundant, and in 1980s in which positive index dominant the precipitation over north china are obvious deficient ; the situation of the yangtse river and huaihe river basin is opposite
流型指數的年代際變化特徵與我國降水的年代際變化趨勢有一定的關系，負指數偏多的60 、 70年代華北降水偏多，而正指數占優勢的80年代華北降水則明顯偏少；江淮流域的情況則相反。 -
3. overexpression of wide - type smads resulted in up - regulation of axudl mrna expression in hepg2 cells, whereas axudl mrna expression was compromised by dominant - negative smad3 ( d407e )
3 .野生型的smad3的過表達能上調h即g2細胞中axudl基因mrna的表達，而smad3蛋白的顯性失活突變子smad3 （ d4o7e ）卻下調其表達。 -
Based on the existing spectral independent component analysis ( spectral ica ) and non - negative constrained decomposition, a moving time window is introduced, and multiple dominant spectral components are extracted within the short - time window
結合已有的頻域獨立成分分析方法以及帶約束的非負分解處理，引入時間滑動窗口，在短時窗內動態提取多重主導功率頻譜。 -
Finally, when the decomposition is proceeding to a symmetric positive definite matrix, the pivot may be very small or even negative. there provided several methods to overcome this shortcoming. ( 2 ) for the block strictly diagonally dominant matrices, there proved the existence and uniqueness of the block lu decomposition and the existence of the incomplete version
（ 2 ）證明了嚴格塊對角占優矩陣塊lu分解的存在唯一性與塊不完全lu分解的存在性，以及嚴格塊對角占優矩陣與不可約塊對角占優矩陣的塊jacobi 、塊gs ，塊sor 、塊ssor等基本迭代法的收斂性。 -
Results : female students rated valence and dominant of the positive pictures higher than male students ; female rated valence and dominant of the negative pictures lower than male students ; meanwhile, female students rated arousal of the negative pictures higher than male students
結果：女性對正性圖片的愉悅度、優勢度評分均顯著高於男性；女性對負性圖片的愉悅度、優勢度評分均顯著低於男性，而喚醒度的評分則顯著高於男性；在中性圖片三個維度的的評分上，均不存在明顯的性別差異。 -
The reasons for such cases include : the conflict between the plural value orientations ; the negative effect of the market economy ; the infiltration of the cultural tradition of " power standard " ; the influnce of the defects of social adjustment mechanism ; the backwardness of moral construction, etc. the optimization of moral quality of the leadership is not only a dominant project in socialist morality construction, but also a systematic one which involves various interacting factors
出現這種狀況的社會原因主要有：多元價值目標的沖突和碰撞；市場經濟的負面效應； 「權力本位」文化傳統的滲透；社會調控機制不全的影響；領導幹部道德建設的滯后等。領導于部道德素質的優化不僅是社會主義道德建設的主導工程，而且是一項諸多因素綜合作用的系統工程。 -
3 using dominant - negative g proteins to study signaling cross - talks
Ignaling蛋白在卵巢內對于 -
My dissertation is divided into four chapters : in chapter one, the historical reasons of the irregular stock structure given by the state - owned shares in absolute dominant position and without circulation as well as the negative impact of it are first talked about. then the background of the task, its roles and difficulties are discussed. finally, a conclusion that the state - owned shares are the fundamental causes for the irregular operations of the capital market is made
本文共分四章：第一章重點討論了國有股一股獨大且處于不流通狀態所造成的股權結構不合理形成的歷史原因，以及其造成的危害；論述了國有股減持的背景、作用及減持所面臨的難點，指出國有股問題是我國股票市場運作不規范的根本性原因。
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