gene modification 中文意思是什麼

gene modification 解釋
基因修飾
  • gene : n. 【生物學】基因。 dominant gene顯性基因。
  • modification : n. 變更，更改，修正；改良，改進；緩和；修改；減輕；限制；【生物學】誘發變異，變態，變體，變型；【語法】修飾；（用變音符號的）母音改變。
  1. The principles, operation and applications of site - directed mutagenesis, gene fusion technology, and post - translational modification methods were introduced emphatically

    著重闡述了基因定點突變技術、基因融合技術和翻譯修飾技術等新興定點固定化技術的原理、特點和操作。
  2. Epigenetic modification of the genome ensures proper gene activation during development and involves : genome methylation changes ; the assembly of histon and histone variants into nucleosomes and remodeling of other chromatin - associated proteins such as linker histones, polycomb group, nuclear scaffold protein, and transcription factors

    這些染色質的再程序化包括dna的甲基化和核小體組蛋白的乙酰化等。組蛋白乙酰化在染色質結構調節、 dna復制、基因轉錄、細胞分化及癌細胞發育都有研究，但在克隆動物中卻是一個有待深入探索的領域。
  3. This novel and efficient vaccine, with the non - cellular structure and no exogenous gene modification, is potential to be not toxic to the recipients. together with characters that it is easy to prepare, this non - cellular vaccine is promising in clinic

    的確，由於exosomes具有非細胞結構、未經基因修飾和外源基因導入、對機體潛在危害作用小、制備簡單易行等優點受到大家的重視，成為研究新型腫瘤生物治療制劑和腫瘤疫苗的新方向。
  4. Part one the studies of piezoelectric biosensors and detection of staphylococcal enterotoxins chapter one the progresses in piezoelectric biosensors and detection of staphylococcal enterotoxins section one the progresses in piezoelectric biosensors in this section, a review is reported with 69 references about the piezoelectric biosensors, including the principle and constitutes of pebs, the classification of pebs, surface modification technique in pebs and the application of pebs in immunoassay, detection of the gene and microorganism, coupling with other techniques, moreover, the development of pebs was involved

    引用參考文獻69篇。第二節金黃色葡萄球菌及其毒素檢測研究進展該部分內容主要介紹了在葡萄球菌分類與分型、金黃色葡萄球菌毒素學研究以及金黃色葡萄球菌及其毒素檢測等方面的研究進展，重點對金黃色葡萄球菌及其毒素檢測方法：生物學檢測方法、免疫血清學方法、聚合酶鏈反應技術、核酸雜交技術、生物傳感器技術和超抗原技術在近幾年的研究進展做了評述，引用文獻69篇。火nxia即。
  5. It was indicated that regulation of 20ahsd activity was not due to post - translational modification by either phosphorylation cycle or glycosylation, but rather at the transcription level of 20ahsd gene expression in previous research papers

    以往研究表明20 hsd活性的調節不是通過糖基化、磷酸化或去磷酸化等翻譯后修飾實現的，而是以轉錄水平的調節為主。
  6. In this study, the suitable parameters for the introduction of plasmids phz1358 and pset152 into s. nanchangensis ns3226 from e. coli were tested for developing an conjugation system for s. nanchangensis ns3226. a dnd gene cluster, which encodes an unknown modification system for 5 hvidans 1326 and renders its dna susceptible to site - specific double - strand dna cleavage during electrophoresis was conjugated from e. coli into s. nanchangensis ns3226

    將克隆在整合型載體pset152上的變鉛青鏈黴菌1326的dnd基因簇通過接合轉移導入野生型南昌鏈黴菌ns3226中進行異源表達，觀察到接合轉移子的dna獲得了在含fe ~ （ 2 + ）的電泳緩沖液中電泳時降解的表型。
  7. According to the cdna of hwtx - v, hwtx - v and mhwtx - v might be come from the same gene. the difference of two toxins may be result from post - translation modification

    根據hwtx -的cdna分析，我們認為這兩個毒素來自於同一個基因，是經過翻譯后加工形成的天然突變體。
  8. Because there are many copies of chloroplast dna and the chloroplast has a strong tolerance to accumulation of the products expressed by the introduced foreign gene, a high level of expression is often happened in chloroplast transformation. in addition, because of prokaryotic property of the chloroplast, the prokaryotic gene can be expressed in chloroplast without any modification and multigene can be simultaneously transferred in " polycistron ", which is impossible in nucleic transformation

    另外，由於葉綠體基因組的原核性質，對來自原核生物的外源基因無需改造就可以在葉綠體內高效表達，而且可以將多個外源基因採取「多順反子」的原核表達形式同時引入，並由共同的啟動子控制，既方便操作又可避免由於存在多個相同啟動子所帶來的「共沉默」 。
  9. Unfortunately, tumor cells can secrete immunosuppressor factors ( such as il - 10, tgf - p, vegf ) to interfere with dc maturation and function. to overcome tumor - mediated inhibition of dc maturation and function in vivo, immunopotentiating cytokines ( such as il - 7, il - 12 ) were used for gene - modification of dc, which has proven to be an efficient way to treat cancer in animal models

    雖然有直接瘤內注射dc誘導抗腫瘤免疫效應的報道，但腫瘤局部往往是一個處于高度免疫抑制狀態的微環境，腫瘤細胞分泌的可溶性介質（如ill 、 tgf卜vegf等）能抑制dc的分化成熟，下調dc表面共刺激分子的表達和iliz的分泌，從而抑制dc的抗原提呈功能，亦對t細胞功能有顯著的抑制作用。
  10. Whereas their parent mutant axr1 - 3 was male fertile, showed moderate insensitivity to ja - inhibitory root growth and mild reduction of ja - inducible gene expression ; parent mutant coi1 - 2 - was a leaky mutant allele of coi !, it exhibited reduced ja insensitivity and partial fertility. - taken together, all these results suggested that scfcoil complex was required for the ja response and that the axr1 - dependent rubl modification of atcull subunit of scfcol " was important for ja signaling in arabidopsis

    試驗結果發現， coil 2 axrl 3雙突變體在根的生長、茉莉素誘導基因的表達和雄性育性方面對茉莉素都表現為完全抗性；而親本coil 2和axrl三突變體對茉莉素均表現部分不敏感性，表明axr基因和coil基因的同時突變協同增強擬南芥對萊莉素的不敏感性， axr基因與coi基因相互作用調控茉莉素的信號傳導途徑。
  11. Gene modification and high prokaryotic expression of porcine interferon alpha

    干擾素的基因改造與高效原核表達
  12. Though the technique of nuclejc transformation in plants has been developed and used widely, some problems in genetic information have not been resolved. for example, because the nucleic genome is so big and complicated that the integration sites and copies of foreign gene can not be controlled accurately, the expression of transferred genes is inefficient as a result of gene silencing or position effect. in nucleic transformation, furthermore, the transfer of multigene is difficult, and only after the prokaryotic genes undergo modification are they expressed in high plants

    植物的細胞核轉化技術已發展成熟並得到廣泛應用，但核基因組的遺傳轉化仍存在一系列至今尚未解決的問題：例如由於核基因組大，背景復雜，外源基因的整合位點和整合的拷貝數難以人為控制，造成鄭州大學2003年博士學位論文杜氏鹽藻（ dunaliellasalina ）葉綠體轉化研究外源基因表達效率低，容易出現基因失活、基因沉默、位置效應等現象;同時轉入多個基因時操作步驟過于復雜，所表達的原核基因必須經過修飾改造，環境安全難以保證等。
  13. With the modification of the method, the technique of differential display ( dd ) has become a very useful method for elucidating changes in gene expression in response to temporal de - velopment, disease and mitogenic stimulants

    在過去幾年裡，出現了許多技術方面的改進，主要集中在增加對於差異表達基因鑒定的效率和降低對于基因鑒定的工作量兩個方面。
  14. " so naturally divergent cats were found and then bred so there is really no modification of the gene.

    「所以我們找出這些有自然差異的貓，再用他們繁殖後代。這不是人為地轉變基因。 」
  15. He said this isa natural genedivergence 13 within the cat dna - one out of50, 000 cats will havethis divergence. so naturally divergent catswere found and thenbred so there is really no modification 14 ofthe gene. in the usalone 38 million households own a cat, andaround the world anestimated one in three humans suffer fromallergies. 1. allergic

    防過敏4 . excrete分泌5 . saliva唾液6 . gland腺7 . urine尿編輯：趙露每日郵報-對于喜歡動物但又對它們過敏的人來說，他們的祈禱應驗了。
  16. Adipokines, the bioactive factors derived mainly from adipocytes, regulate pancreatic - cell function including insulin secretion, gene expression and apoptosis. in this review, we propose that adipokines influence - cell function through three interdependent pathways. the first is through regulating lipid and glucose metabolism in - cells. the second implicates the change of ion channel opening and closing in - cells. the third pathway is via the modification of insulin sensitivity of - cells. the endocrine function of adipocytes is dynamic, and the secretion of various adipokines changes under different metabolic conditions. during the progression from the normal state to obesity and to type 2 diabetes, adipokines contribute to the occurrence and development of - cell dysfunction in type 2 diabetes

    脂肪因子包括脂肪細胞分泌的多種活性因子，它們通過內分泌方式調節胰島細胞的胰島素分泌、基因表達以及細胞凋亡等多方面的功能.本文提出脂肪因子影響胰島細胞功能主要通過三條相互聯系的途徑而實現.第一是調節細胞內葡萄糖和脂肪的代謝;第二是影響細胞離子通道的活性;第三是改變細胞本身的胰島素敏感性.脂肪細胞的內分泌功能是一個動態過程，在不同的代謝狀態下，各脂肪因子的分泌發生不同變化.從正常代謝狀態發展到肥胖以及2型糖尿病的過程中，脂肪因子參與了胰島細胞功能障礙的發生與發展
  17. Abstract : adipokines, the bioactive factors derived mainly from adipocytes, regulate pancreatic - cell function including insulin secretion, gene expression and apoptosis. in this review, we propose that adipokines influence - cell function through three interdependent pathways. the first is through regulating lipid and glucose metabolism in - cells. the second implicates the change of ion channel opening and closing in - cells. the third pathway is via the modification of insulin sensitivity of - cells. the endocrine function of adipocytes is dynamic, and the secretion of various adipokines changes under different metabolic conditions. during the progression from the normal state to obesity and to type 2 diabetes, adipokines contribute to the occurrence and development of - cell dysfunction in type 2 diabetes

    文摘:脂肪因子包括脂肪細胞分泌的多種活性因子，它們通過內分泌方式調節胰島細胞的胰島素分泌、基因表達以及細胞凋亡等多方面的功能.本文提出脂肪因子影響胰島細胞功能主要通過三條相互聯系的途徑而實現.第一是調節細胞內葡萄糖和脂肪的代謝;第二是影響細胞離子通道的活性;第三是改變細胞本身的胰島素敏感性.脂肪細胞的內分泌功能是一個動態過程，在不同的代謝狀態下，各脂肪因子的分泌發生不同變化.從正常代謝狀態發展到肥胖以及2型糖尿病的過程中，脂肪因子參與了胰島細胞功能障礙的發生與發展
  18. The pattern of gene expression that makes this transformation possible relies heavily on two phenomena : modification of chromatin and alternative splicing

    造成這種轉變的基因表現模式，可能大量仰賴了兩種作用：染色質修飾和選擇性剪接。
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