nerve transmission block 中文意思是什麼

nerve transmission block 解釋
神經傳遞阻滯
  • nerve : n 1 【解剖學】神經。2 〈詩〉筋 腱；精力 氣力。3 膽力 勇氣；沉著 果斷；大膽 膽量；〈口語〉厚臉 冒...
  • transmission : n 遞送；傳遞；傳達；傳染；移轉；【機械工程】傳動；傳遞；變速器；聯動機件；【無線電】傳送；發射；...
  • block : n 1 片，塊，大塊；粗料，毛料；木料；石料；金屬塊；【建築】塊料，砌塊；【地質學；地理學】地塊。2 ...
  1. The toxin can reversible block the neuromuscular transmission in an isolated mouse phrenic nerve - diaphragm preparation and also is a neurotoxin ( n - type ca2 + channels inhibitor ) which binds to the postsynaptic nicotinic acetylcholine receptor ( nachr )

    溶液構象研究表明，它採取自然界中其它蛋白質多肽普遍採用的一種緊湊、緻密的抑制劑胱氨酸結模體（ ick ） 。
  2. After renaturation, the biological activity of mviia is nearly 100 % of that of natural one ; the activity of hm - 1227 is less than t | iat of hwtx - i ; however, hm - xw cannot block the neuromuscul ar transmission in an isolated mouse phrenic nerve - diaphragm preparation

    復性后的mv a摘要生物學活性接近天然mvlla的100 % ;嵌合體hm一1227的活性小於hwtx一i的15 % ;而嵌合體fd以一xw不能阻斷小鼠隔神經一隔肌的接頭傳遞。
  3. The sequence of hntx - v had been determined by 491 sequencer : nh2 - eclgfgkgcnpsdqccksanlvcsrkhrwckyei - cooh, in which there were 35 amino acid residues and six cys. the toxin could block neuromuscular transmission in an isolated mouse phrenic nerve diaphragm preparation. hntx - v is a natural mutant of hntx - iv, for there is only one different residue ( ala20ser )

    Hntx -經491測序儀測得其氨基酸組成為： nh2 - eclgfgkgcnpsdqccksanlvcsrkhrwckyei - cooh ，含35個氨基酸殘基， 6個半胱氨酸全部參與了二硫鍵的形成，該毒素對小鼠膈神經-膈肌標本有阻遏作用。
  4. 46da, respectively. the sequences of the two toxins are determined and found to consist of 34 and 36 amino acid residues, respectively. both of the two sequences include six cys residues, which form three disulphide bonds. jztx - can block neuromuscular transmission in an isolated mouse phrenic nerve diaphragm

    Jztx -對電刺激誘導的小鼠膈神經-膈肌收縮產生抑制作用，濃度為1 . 0 10 ~ （ - 6 ） mol / l時的阻斷時間為15分鐘左右，對鈉通道和延遲調整型鉀通道的激活和失活沒有影響。
  5. Mass spectrometry of synthetic hw - ma and rgd - hw are in full agreement with those speculated theoretically, which proves the success of peptide synthesis and refold. on isolated mouse phrenic nerve - diaphragm preparations, hw - ma can block the neuromuscular transmission in 35 minutes or so ( l 10 - 5 g / ml ), its biological activity shows 73 % decrease comparing with biological activity of native hwtx - i. it proves t hat the protein engineering of synthetic chimera hwtx - i has gained success to some extent, although it did not achieve our expectations. thus it proved that hwtx - i can be using as natural scaffold for protein engineering. and also emphasized the importance of " local stereo circumstances " of activity site when the foreign activity site was transferred into a natural scaffold

    濃度為1 / 1059 / ml的hw一ma突變體能可逆阻斷小白鼠隔神經書高肌的接頭傳遞，阻斷時一間為35min左右，與天然hwtx一i比較，生物學活性下降3一4倍，說明合成的突變體改造獲得了一定的成功，盡管與我們預期的目標有一定的差距，從而證明hwtx一i可以作為蛋白質工程研究的天然分子骨架，同時也強調了往天然分子骨架中轉移外源活性位點時維持活性位點「局部立體環境」的重要性。
分享友人
分享到 Line

分享到臉書