nuclear protein 中文意思是什麼

nuclear protein 解釋
核內蛋白
  • nuclear : adj 1 核的，成核的；有核的。2 【物理學】原子核的；原子能的；原子彈的；核動力的。3 〈比喻〉核心的...
  • protein : n. 【化學】朊，蛋白（質）。
  1. Egfr protein located on cell membrane, nuclear membrane and in the cytoplasm, characterized in both syncytiotrophoblast and cytotrophoblast

    Egfr存在於妊娠各期滋養層細胞的細胞膜、核膜及胞質中，其中細胞膜表達最強。
  2. Mint ( msx2 - interacting nuclear target protein ) can interact with rbp - j and msx2 ( the murine homologue of drosophlia muscle - segment homeobox ), and represses their transcription activation activity

    進一步的研究表明mint可以與n成ch受體的胞內段競爭結合rbp j ， n而抑制rbp刁的轉錄激活作用。
  3. They are involved both in the production of mature proteins, acting as processing enzymes, and in the degradation of damaged or non - functional proteins [ 1 " 8l in plant plastids, proteases function in protein degradation seem to act to adjust the stoichiometry of subunits in supramolecular complexes, as well as to regulate the stoichiometry between different supramolecular complexes in response to environmental changes and process the nuclear - encoded preproteins in the stromal

    除了在相關蛋白質轉錄和翻譯方面的調控外，專一降解這些蛋白的蛋白酶活性以及轉錄翻譯量的上升也會加強對這些蛋白質的降解。雖然到目前為止對光系統中蛋白酶的了解尚且不如對光系統中各種多肽以及蛋白色素復合體的了解，但是對類囊體和葉綠體中蛋白酶的研究已經進展到相當深度了。
  4. The targeted disruption of mouse rbp - j revealed that homozygous null mutants die before 10. 5 days postcoitum ( dpc ) with various abnormalities, including growth retardation and defects in the central nervous system and somites. in order to assess the function of rbp - j, a yeast two - hybrid screening using rbp - j as a bait protein was performed and a nuclear matrix protein, mint was isolated

    Sdpc胚胎和人的hela細胞cdna文庫中篩選到一個可以與rbp斗相互作用的新蛋白ram7 ，后發laram7與mmt （ msxz inter肌tingnucleartargetprotein ）為同一蛋白。
  5. To search proteins that associate with the mouse mint protein and regulate notch signaling in nuclei, and to study the function and mechanism of mint - mediated transcription repression, yeast two - hybrid assay was used to screen proteins that interact with a fragment of mint ( f5, amino acids 2226 - 2959 ). from 4x106 yeast clones transformed with the bait plasmid and a cdna library of 9 dpc mouse embryo, fifty - one were positive for nutritional screening and p - galactosidase assay. restriction digestion identified 10 independent positive clones and these were analyzed by dna sequencing these clones represent 3 correctly fused cdna fragments, which are mint, alpha a - crystallin - binding protein i ( alphaa - crybpl ), and nuclear receptor co - repressor 1 ( n - corl ), respectively

    鑒于mwt基因編碼區較長，共有10799個堿基，故此我們將mint分為六段，分別命名為fi一f6 ，本研究以其中的f5 （ 222e959 ）和f6 （ 296s576 ）片段為研究對象，將h者分別插入pgb盯7載體中，結果顯示： mintfs可與核受體輔助抑制因子1階cori ） ， o晶狀體蛋白結合蛋白1hlphatcrybp入及mw加互作用，而f6可與igm的重鏈恆定區、泛素結合酶2l6和一個未知功能的新的蛋白基因進行結合。
  6. Cell microscopy studies at embl heidelberg reealed that the human nuclear transport protein, importin alpha, recognises this signal and shuttles the polymerase into the nucleus

    在海德堡歐洲細胞生物學實驗室里的細胞顯微鏡檢查法的研究顯示了人類核轉運蛋白，輸入蛋白能識別這種信號並且能夠把這種多聚酶運送進細胞核
  7. Production of transgenic embryos expressing green fluorescent protein by nuclear transfer from different types of somatic cells in pig

    不同類型的轉基因細胞為核供體生產豬的轉綠色熒光蛋白基因克隆胚胎
  8. Epigenetic modification of the genome ensures proper gene activation during development and involves : genome methylation changes ; the assembly of histon and histone variants into nucleosomes and remodeling of other chromatin - associated proteins such as linker histones, polycomb group, nuclear scaffold protein, and transcription factors

    這些染色質的再程序化包括dna的甲基化和核小體組蛋白的乙酰化等。組蛋白乙酰化在染色質結構調節、 dna復制、基因轉錄、細胞分化及癌細胞發育都有研究，但在克隆動物中卻是一個有待深入探索的領域。
  9. The protein product of meq gene was highly expressed in the nuclei of recombinant baculovirus infected sf9 cells when using an anti - meq monoclonal antibody ( mcab ) 23b46 to run the immunofluorescence assay ( fa ) ; the expression quantity and if staining patterns differed with different times post - infection ( pi ). the results of western blotting and immunoprecipitation test showed there were two specific bands around 60 kd. the results of the study demonstrated that the baculovirus / insect cell system is effective to be used to express nuclear protein of virus

    結果發現:本表達系統產生的meq蛋白可被重組痘病毒表達的meq制備的單抗23b46所識別;在感染細胞中， meq蛋白僅局限於細胞核內，而且隨著感染后（ pi ）時間的增加，具有從核質向核仁和核膜轉移的趨向; w已stemblot和免疫沉澱試驗均證實重組桿狀病毒感染細胞裂解物中出現有兩條大小約為60kd的特異帶。
  10. Obtaining structure and function of proteins is one of the main purposes of research in biology, but determining three - dimensional structure of protein by means of x - rays crystallography and nuclear magnetic resonance spectroscopy, and research in protein structure by the way of biochemistry, already can ’ t adapt the need of the rapid increase of protein sequence

    獲取蛋白質的結構和功能是生物學研究的重要目的之一，但是使用x光晶體衍射和核磁共振技術等實驗手段測定蛋白質的三維結構，以及使用生物化學方法研究蛋白質的功能時效率不高，已經無法適應蛋白質序列飛速增長的需要。
  11. The cells were then stimulated with various concentrations and incubation times of oligochitosan to study dose - dependent and time - dependent manners. the effect of oligochitosan on the production of no released by raw264. 7 cells was evaluated by griess method, which was also used to evaluate the effect of nf - kb inhibitor on no production induced by oligochitosan. western blot was performed to detect the protein content of nf - k b in the nuclear extract

    本課題以小鼠單核/巨噬}炎魏細胞raw264 . 7為研究對象，觀察殼寡糖單獨作用於巨噬細胞對其產生no的影響，並初步探討了核轉錄因子一kappab （ nf一kb ）在這過程中的作用，旨在部分解釋殼寡糖對免疫系統調節作用的機理，為其在醫學上的應用提供理論依據。
  12. Tissue sections from every animal were double - labeled with the antibodies of map - 2, cox - 2, gdnf, caspase - 3 and either the neuron - specific antibody neuronal nuclear protein ( neun ) or the astroglial - specific marker glial fibrillary acidic protein ( gfap ). we carried out a series of research to explore the effects and mechanism of map - 2, cox - 2, gdnf, caspase - 3 during tbi and trie d to provide some useful theory basis for both the treatment of tbi in the practice and forensic medicine

    並通過上述指標分別與神經元特異性標志物神經元核蛋白（ neuronalnuclearprotein ， neun ）和星形膠質細胞特異標志物膠質纖維酸性蛋白（ glialfibrillaryacidicprotein ， gfap ）進行免疫組織化學雙染色，探討腦損傷后神經元及神經膠質細胞反應性變化情況及其分子生物學機制，以期為腦損傷研究提供有益的數據材料，也為以上指標在法醫學實際檢案的應用提供必需理論依據。
  13. Fghrl and zfghrl : we failed to find out the 5 " ends nuclear acids due to a incomplete genome sequences. the fghrl consists of 1755bp and encodes a 584 amino acid protein

    東方?和斑馬魚ghr1 ：由於東方?基因組測序工作沒有完成的原因，本研究沒有分離出fghr1cdna5 』末端的部分。
  14. According to the amino acid sequence resulted from our previous research about tb22kda protein and the related literatures about gene sequence of allergenic protein in common buckwheat, we designed primers and got the structure gene successfully. by 3 ' - race method combined with nested pcr, the 3 ' - end nuclear acid sequence was also obtained ; in additon, for the 5 ' - end sequence, we selected a specific conserved nuclear acid sequence as the 5 ' primer and part of structure gene sequence as the 3 " primer, and till now, partial 5 ' - end sequence has been amplified as well

    本研究根據先前分離純化所得天然tb22kda蛋白經maldi - tof - ms （質譜法）測得的氨基酸序列和文獻報道的過敏蛋白核苷酸序列設計引物，擴增克隆了該過敏蛋白結構基因的編碼序列；根據測得的序列設計特異性引物，並利用3 』 - race方法結合巢式pcr擴增得到基因的3 』末端；依據同源性比較的結果選用一段保守序列為5 』引物，並根據結構基因內部序列設計3 』特異性引物，進一步獲得了該基因5 』端的部分序列。
  15. As cyclin b is the mark protein representing the process of prophase, we infered that cytochalasin b destroyed the polymerization of the nuclear actin and directly affected the process of prophase. nuclear actin played an important role in the process of the chromosome construction

    因為cyclinb是有絲分裂前期進程的標志性蛋白，所以我們認為細胞鬆弛素b破壞細胞核內肌動蛋白聚合后，直接影響了有絲分裂前期的進程，進而悅明核內肌動蛋白在有絲分裂前期染色體構建過程中起著重要作用。
  16. The activity of the antiserum was tested by dot enzyme immunization assay ( diba ) with purified antigen. western blot of hela nuclear protein extract, which contained natural hbaf53, showed that the antiserum is also a specific antiserum to natural hbaf53. therefore the highly specific and sensitive antiserum can be applied to various studies

    用純化的抗原蛋白，經斑點印跡試驗測得baf53抗血清的效價，又用提取的hela細胞核蛋白（含有天然baf53蛋白）進行免疫印跡分析（ westernblotting ） ，證明天然baf53蛋白也是該抗血清的抗原，說明獲得的多抗血清具有高特異性和敏感性，可用於多方面的研究。
  17. Identified as encoding protein that bind msx2, mint, human gene termed as sharp ( smrt / hdac1 associated represser protein ), is a large nascent polypeptide of 3576 amino acids and has three n - terminal rna recognition motifs ( rrms ) and four nuclear localization signals

    Mint屬於一個新的spen （ splitends ）蛋白家族成員。 spen是果蠅中一個分子量為600kda的巨大核蛋白，參與果蠅發育過程中神經元蟬的決定和神經元突起延伸的調節。
  18. By nuclear transferee transfered the nih 3t3 cell to enucleated gv and mii oocyte. the immunofluorescence results showed that jak. 2 was not transfered to somatoblast nuclear whether the recombined oocyte occured gvbd or not. when transfered somatoblast nuclear to enucleated and integrated m ii oocyte, the immunofluorescence results showed that jak2 only existed in the nuclear of integrated m ii oocyte but not the somatoblast nuclear. the nuclear transfer implied that the mature and immature oocyte cytoplasm could not transfer the jak. 2 protein to donor nuclear

    通過核移植，將nih3t3體細胞核移入去核gv期和m期的卵母細胞中。熒光檢測發現，體細胞核與去核gv期卵母細胞質構成的重組卵無論是否發生gvbd ，核內均沒有jak2的出現。在去核和未去核的m期卵母細胞中移入體細胞核， jak2僅存在於未去核m期卵母細胞的核內，並不轉移到體細胞核內。
  19. The axudl gene consists of five exons and encodes a nuclear protein with 63kd molecular weight. it was frequently down - regulated in lung, kidney, liver and colon cancers compared with their corresponding normal tissues

    該基因含有五個外顯子，其編碼產物為分子量63kd的細胞核內蛋白，該基因在肺癌、腎癌、肝癌和結腸癌中的表達較相應的正常組織均明顯降低。
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