telomerase activation 中文意思是什麼

telomerase activation 解釋
端粒酶活性
  1. Comparison of telomerase activity in a few cell lines showed that application of dna sequencer in detecting telomerase enzyme activity is applicable in quantitative and qualitative determination of telomerase activity. the result of this method could be available within 4 - 5 hours with high sensitivity and less handling time. it provided a reliable means to study on regulative mechanism of telomerase activity and relationship between telomerase activation and malignancy

    Trap與dna測序相結合檢測端粒酶活性的方法,操作簡便、快速、經濟、無放射性危害,可在3 ? 4小時內得到檢測結果,大大縮短了檢測時間,為研究端粒酶活性的調節機制、端粒酶與惡性腫瘤之間的關系以及臨床上鑒別和診斷腫瘤的良惡性提供了一種檢測手段。
  2. Telomerase is a new target of oncotherapy, the growth of tumor could be repressed by restraining telomerase activation

    端粒酶已成為新的腫瘤標志物及腫瘤治療的新靶點,抑制腫瘤細胞端粒酶活性可望達到抑制腫瘤生長的目的。
  3. We summarize the dual role of telomeres in cancer, and the relationship between telomerase activation and tumours

    筆者綜述了端粒的縮短所扮演的雙重角色,以及端粒酶的激活與腫瘤之間的關系。
  4. When mms was added directly to s. cerevisiae s288c cell extracts immediately before primer addition, telomerase activity remained unchanged. thus, a direct influence of mms on trap assay does not seem to be involved in telomerase activation observed after drug treatment

    如果在加人引物之前將mms直接加在釀酒酵母5288c細胞蛋白提取物zh ,結果顯示端粒酶活性沒有變化,因此排除了mms對端粒酶的直接激活作用。
  5. Telomerase is a celler reverse transcriptase which catalyzes the synthesis and extension of telomeric dna. telomerase activation is not observed in normal tissues of somatic origin but in almost 90 % of human cancer, with the result the telomere shorten progressively with cell division and thus is a critical step for multistep carcinogenesis

    正常人體細胞(非生殖細胞)中端粒酶活性的表達很低,或用目前的方法幾乎檢測不到,而在90以上的惡性腫瘤中可檢測到端粒酶活性,相應的良性腫瘤則為陰性或僅有少數陽性。
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