transmembrane protein 中文意思是什麼
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For example, the signal transduction of g protein - coupled receptor is mediated by g protein and can generate intracellular messages ; there exist some transmembrane proteins in the membrane of endoplasmic reticulum, and some of them are related with the synthesis and transportation of some proteins, while others are related with substance metablism, such as glucose - 6 - phosphatase ( g6pase ). in addition, after binding with the 7 - tm receptors affiliated to frizzled protein family, wnt can activated disheveled protein in cytoplasm which is essential to embryonic development
如g蛋白偶聯受體通過g蛋白介導產生胞內信使（ camp ， cgmp ， dg ， ip _ 3 ）將胞外信號傳遞到胞內，從而引起生物學效應；內質網上也存在著一些跨膜蛋白，其中一些與蛋白質的合成及運輸有關，一些與物質代謝有關，如葡萄糖- 6 -磷酸酶。 -
The predicted secondary structure of the protein displays multiple putative transmembrane domains
1 。計算機軟體分析表明，其編碼的蛋白具有多次跨膜樣結構域。 -
The env protein deduced from env gene encodes the hydrophilic surface protein ( su ) and the hydrophobic transmembrane domain ( tm ) that determine the specific interaction between virus particles and cell surface receptors during retroviral entry. the su of retroviruses is a highly variable genetic element, containing receptor binding sites and major antigenic determinants. exjsrv - specific dna probes were derived. by using these dna probes in tissue hybridization. we successfully identified jsrv mrna expression and proviruses dna in sheep lung tissues infected with jsrv and control group has no postive signals, validating the use of exogenous virus - specific dna probes in the analysis of oncogenic proviral integration sites and identification of integrated exogenous proviral sequences
用地高辛隨機引物法標記exjsrv特異的env片段，制備探針，原位雜交檢測spa肺組織中的rna及前病毒dna ，結果表明spa患羊肺組織內有jsrvenv基因mrna的表達，同時也檢測到了前病毒dna ，而相應的陰性對照卻無陽性信號，證實外源性病毒特異的dna探針在致瘤性前病毒的整合位點和整合的外源性前病毒的檢測中具有可信度。 -
We fused the gfp into the c - terminal region as well as n - terminal region of emt - 1 protein. the result showed that the localization of the protein encoded by the full length emt - 1 cdna was in endoplastic reticulum ( er ). extracellular region, transmembrane and intracellular region showed the similar cellular localization
我們用綠色熒光蛋白融合於emt l全長及其不同截斷形式的梭基和氨基端，瞬時轉染cos 7細胞，通過熒光顯微鏡觀察，發現emt l編碼的蛋白呈現內質網定位的特點。 -
The transmembrane activity of the ptd of tat protein fused at the carboxyl - terminus of gfp in vivo
端融合在活體體內的跨膜遞送作用 -
G - protein - coupled seven - transmembrane receptor
七次跨膜g蛋白耦聯受體 -
Our previous work verified that heterotrimeric g protein was involved in regulation of pollen germination, tube growth and in the transmembrane mechanism of extracellular cam signal. in the present study, we provide further evidence that plc signaling pathway was presented in lily pollen and involved in extracellular cam signal transduction mechanism in pollen by molecular, biochemical and physiological approaches. these evidence included : the pip _ ( 2 ) - dependent plc activity was also detected in purified lily pollen protoplasts
為了給上述信號轉導過程提供進一步的證據，本文以百合花粉為材料，從plc活性的測定、 plc基因的克隆及其與花粉萌發的關系、以及plc活性被g蛋白和cam調控等方面，為肌醇磷脂系統參與花粉萌發和細胞外鈣調素的信號轉導過程進一步提供了分子生物學和生物化學的證據。 -
It is divided to extracellular and intracellular part by transmembrane domain. there are 13 n - glycosylation sites, 20 protein kinase c phosphorylation sites, 28 casein kinase ii phosphorylation sites, 4 tyrosine kinase phosphorylation sites and 15 n - myristoylation sites in the extracellular part of bt - r3 protein. an integrin recognition sequences rod lies in intracellular part of bt - r3 protein
跨膜區域（ tmd ）將它分為胞內和胞外兩個部分，它的胞外有13個潛在的糖基化位點， 20個蛋白激酶c的磷酸化位點， 28個酪蛋白激酶的磷酸化位點， 4個酪氨酸酶的磷酸化位點， 15個豆蔻（十四烷基）酰化位點；它的胞內有1個整合蛋白（ integrin ）識別位點。 -
Hydrophobicity analysis suggested that the v - h + - atpase subunit c from 5. salsa was a transmembrane protein with four transmembrane domains. earlier experiments indicated the conserve glutamyl residue in the fourth transmembrane domains might participate in the proton translocating across the membranes
鹽地堿蓬液泡膜h ~ + - atpasec亞基第四個跨膜區存在高度保守的谷氨酸殘基，先前的研究表明此谷氨酸殘基可能與h ~ +跨脂雙層運輸有關。 -
The single peptide of bt - r3 protein is a a helix which orients from inside to outside, and the transmembrane domain is also a helix which orients from outside to inside
Bt - r3受體蛋白最前端的信號肽是一個由內向外a螺旋，跨膜區域（ tmd ）是一個由外向內的a螺旋。 -
Cystic fibrosis is caused by mutations in the gene encoding an ion - transport protein, the cystic - fibrosis transmembrane conductance regulator ( cftr ). defective secretion of anions is the primary cause of many of the clinical manifestations of cystic fibrosis, including pancreatic insufficiency
囊性纖維化是由作為陰離子通道的跨膜電導調節器（ cftr ）的基因突變所致，而陰離子分泌缺損是囊性纖維化的多種臨床表現（包括胰腺功能缺陷）的主要原因。 -
Professor hsiao - chang chan is a leading authority in epithelial cell - related multidisciplinary research and has contributed significantly to a number of important discoveries, including a cell shrinkage - activated cation channel, a novel defensin molecule in the epididymis for sperm maturation and the role of a cell membrane protein, the cystic fibrosis transmembrane conductance regulator cftr, in fertility and infertility
陳小章教授是上皮細胞相關的跨學科研究權威學者，曾作出過多項突破性科學發現，包括細胞收縮激活的陽離子通道的發現、從附睪頭部分泌的一個新防禦及其對精子成熟的影響以及囊性纖維化跨膜電導調節器在生殖及不育中的角色。 -
One of them was identified as the beth gene of halobacillus sp. d8. a hydrophobicity plot of beth revealed an alteration of hydrophobic and hydrophilic segments that was characteristic for integral membrane protein, suggesting the presence of 12 transmembrane - spanning segments and belonged to bcct family
將重組質粒測序，插入片段大小為4kb左右，通過blast比較，結果顯示含有三個orf框，其中一個為甘氨酸甜菜堿轉運蛋白，對其氨基酸組成進行疏水性分析，推測為含有12個跨膜域的跨膜蛋白，屬于bcct家族。 -
Genetic association between polymorphism of claudin 5 transmembrane protein gene and schizophrenia
膜轉運蛋白基因單核苷酸多態性與精神分裂癥 -
Haake da, champion ci, martinich c, et al. molecular cloning and sequence analysis of the gene encoding ompl1, a transmembrane outer membrane protein of pathogenic leptospira spp [ j ]. j bacteriol, 1993, 175 ( 13 ) : 4225
晏菊芳，鮑朗，伍衛華，等.中國鉤端螺旋體強毒株017膜蛋白基因的質粒載體構建及表達[ j ] .中華微生物學和免疫學雜志， 1999 ， 99 （ 2 ） : 117 -
In this pathway, irel, an er transmembrane protein kinase / endoribonuclease, is essential for viability during er stress. in contrast to yeast, the mammalian genome contains two homologues of ire1, irelctand ire1b, to sense the unfolded protein level
該基因的開放讀碼框（ openreadingfiame ， orf ）為1383bp ，編碼蛋白的大小為50kd ，大腸桿菌ibeb基因編碼的50kd前體蛋白經分子內剪切加工形成大小為34kd的成熟表達產物，定位於細胞外膜。 -
Hydrophobicity and transmembrane domain analysis show that the protein encoded by orf1 contains five hydrophobic domains and four transmembrane domains. it maybe a transmembrane protein
經疏水性和跨膜區分析， orf1編碼的蛋白含有5個疏水區、 4個跨膜區，應為跨膜蛋白。 -
Hydrophobicity analysis of the noeb showed that it is a transmembrane protein and includes four transmembrane regions at n - terminal., consisting of three primary helixs and one secondary helix
疏水性分析發現， noeb是一個跨膜蛋白，在n末端有4個跨膜區，其中包含3個初級螺旋和1個次級螺旋。 -
Notch proteins are a family of evolutionarily conserved transmembrane receptors which are involved in cell fate determination of many cell lineages. notch ligand delta is also transmembrane protein with characteristic cysteine - rich n - terminal domain responsible for notch binding
Notch基因廣泛表達于胚胎發育過程中的各種組織和各種成熟組織中具有增殖能力的細胞層，該基因編碼一個由2753個氨基酸殘基的型跨膜蛋白分子受體，其配體也是細胞膜蛋白，稱為delta 。 -
Hydrophobicity analysis predicted a 36 - residue hydrophobic signal peptide for secretion in the n - terminus, and no transmembrane region was present, suggesting it might be a type of secretory protein. some generic and atipical n - glycosylation sites were present in clsp, suggesting that the protein might represent a glycoprotein. the clsp protein contained one cub ( clr / cls, an embryonic sea urchin protein uegf, and bone morphogenetic protein i ) domain from 39th to 164th ammo acids, which is known to be involved in protein - protein or protein - substrate interaction, and a trypsin - like serine protease domain positioned from 244th to 483rd amino acids
Clsp分子具有補體樣絲氨酸蛋白酶的多種結構特徵，包括36個氨基酸組成的疏水信號膚，一個cub （ clr / cls ， anembryonicseaurehinproteinuegf ， andbonemorphogeneticproteinl ）結構域和一個胰酶樣絲氨酸蛋白酶結構域（ t汀psin一likeserineproteasedomain ）和幾個保守的糖基化位點等，沒有發現有跨膜區的存在。
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