tumor cell lines 中文意思是什麼
tumor cell lines
解釋
腫瘤細胞系-
The b lymphocyte stim lator ( blys ) also known as baff, tall - 1, thank, ztnf4, is the most recent addition to the tumor necrosis factor family ( tnf ) ligands. blys induces both in vivo and in vitro b cell proliferation, differentiation and immunoglob lin secretion. meanwhile, it also strongly suppresses the growth of tumor cell lines. the over - production of blys is associated with the development of certain autoimmune disease, such as systemic lupus erythaematosus ( sle ), rheumatoid arthritis, myasthenia gravis, sj greh ' s syndrome
人b淋巴細胞刺激因子（ hblys ）是1999年發現的腫瘤壞死因子超家族成員。最早發現其可誘導腫瘤細胞凋亡，之後發現它是一個強有力的b細胞共刺激因子，它在體外及轉基因動物體內可明顯刺激b細胞的生長，免疫球蛋白分泌，並導致動物自身免疫性改變。 -
Mdr1 express product p - glycoprotein was detected by immunocytochemical method and flowcytometry. the cytotoxicity and multidrug resistance reversion effect of tea polyphenol was examined by mtt assay in mcf - 7 and mcf - 7 adr carcinoma cell lines, and compared with pgp inhibitor quinidine. the pgp expression of mcf - 7 adr was strongly positive, the positive rate was 15 % ; the pgp expression of mcf - 7 was negative, the positive rate was 1. 8 %. ic50 of tea polyphenol to mcf - 7 and mcf - 7 adr is 115. 2g ml and 207. 6g ml respectively. ic50 of quinidine to mcf - 7 and mcf - 7 adr is 129. 8mol l 42. 1g ml and 94. 1mol l 30. 5g ml respectively. tea polyphenol and quinidine changed little toxicity of adriamycin to mcf - 7, but tea polyphenol and quinidine improved the sensitivity of mcf - 7adr to adriamycin significantly. immunocytochemistry and flow cytometry can detect p - glycoprotein expression level qualitatively and quantitatively. tea polyphenol is not only an anti - tumor agent, but also a multidrug resistant modulator similar as quinidine. tea polyphenol is advantageous for its little toxicity in tumor treatment
用免疫組化法和流式細胞儀對腫瘤細胞系mcf - 7和mcf - 7 adr的p -糖蛋白表達水平進行定性定量研究。用噻唑藍比色法mtt研究茶多酚的細胞毒性及其對耐藥性的逆轉作用，並與pgp抑制劑奎尼定進行了比較。免疫組化法檢測p -糖蛋白表達水平， mcf - 7 adr呈強陽性，而mcf - 7呈陰性流式細胞儀定量檢測結果mcf - 7 adr細胞系細胞陽性率為15 % ， mcf - 7細胞系細胞陽性率為1 . 8 % 。 -
A lectin named pclii with multi - functions was isolated from the rhizomes of polygonatum cyrtonema hua, a liliaceae plant used as traditional chinese herbal medicine. pclii can bind mannose and silia acid, it also can agglutinate rabbit erythrocytes and gastric tumor cell lines sgc and hsc strongly and inhibite the growth of some pathogens. pclii is a strong mitogen toward human t - lymphocytes and an efficient ca2 * antagonist ( ca ) or ca2 + channel blocker ( ccb )
百合科植物囊絲黃精（ polygonatumcyrtonemahua . ）是我國傳統中草藥，其根狀莖中含有一種凝集素，命名為黃精凝集素（ polygonatumcyrtonemahua . lectin ，簡稱pcl ） ，具有特異性結合甘露糖和唾液酸以及凝集兔紅細胞、促t細胞有絲分裂等活性。 -
Effects of mycobacterium phlei combined with anti - tumor drugs on human lung cancer cell lines
草分枝桿菌聯合化療藥物對人肺癌細胞生長抑制作用的研究 -
Inhibitory effects of paeonol on the proliferation of four tumor cell lines
丹皮酚在體外對4種腫瘤細胞株的增殖抑制作用 -
The originalities of this paper are : 1, development of a a flow cytometry - based assay for quantitative analysis of cellular proliferation and cytotoxicity in vitro ; 2, the soluble secretion of k. 562 cell lines reduce the number of pbmc, but promote the activity of pbmc in dose - dependent manner ; 3, soluble secretion of k562 cell lines can induce the no production by pbmc, but no only plays a part of the role of soluble secretion of k562 cell lines ; 4, establishing a in vitro model and giving some parameters for sreening and appraising anti - tumor medicine
本研究的創新點在於： l 、建立了用流式細胞術定量測定細胞增殖和細胞毒性的直接檢測技術； 2發現k562可溶性分泌物劑量依賴性地使pbmc細胞數量減少但活性增加； 3 、 k562可溶性分泌物能誘導pbmc產生no ，但是no的作用並不等同於腫瘤上清的全部作用。 4 、為抗腫瘤藥物篩選提供了一個體外模型，並明確了一些篩選指標。
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