tumor-suppressor 中文意思是什麼
tumor-suppressor
解釋
腫瘤抑制器- tumor : n. 【醫學】腫瘤，癌，疙瘩，贅疣。 a benign [malignant] tumor 良[惡]性腫瘤。adj. -ous 腫瘤的；誇張的 （tumorous growth 【農業】陡長）。
- suppressor : n. 鎮壓者；隱蔽者；禁止者；刪除者；抑制因子；【物理學】消聲器；【無線電】抑制柵極。
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In addition, axud1 has a high homologue with transforming growth facotr beta ( tgf - ) induced apoptosis protein 2 and 12 using blast exploration at genebank database. these suggest that axudl may have a tumor - suppressor function in these organs and may play an important role in tgf - - induced apoptosis
通過genkbank上blast的搜索結果表明， axud1與tgf -誘導的凋亡蛋白2 、 12 （ taip - 2 、 taip - 12有較高的同源性，提示axud1可能是一個具有腫瘤抑制功能的基因，並可能在tgf -誘導的細胞凋亡中起著重要作用。 -
In 2005, researchers at sloan - kettering reported that the gene could stop massie tumor growth in prostate cancer een when another tumor suppressor, known as p53, was turned off
早在2005年，斯隆-凱特琳中心的研究人員就曾報道了在另一種叫做p53的腫瘤抑制基因關閉時，該基因甚至仍然可以阻止前列腺癌大腫瘤生長。 -
The gene, called rassf1a, is a tumor - suppressor gene
這個基因叫rassf1a基因，是一個抑癌基因。 -
Preliminary study on transformation of tumor suppressor gene p53 into tomato
53導入番茄的初步研究 -
Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues, and in this situation, the ccc has been disrupted and cell adhesion function disturbed. a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc, and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription
當-連環蛋白酪氨酸或絲氨酸殘基磷酸化后，就與ajs發生解離而游離到細胞漿中，此時細胞的粘附功能也發生障礙，游離到胞漿中的-連環蛋白，一部分被抑癌因子apc降解，一部分則轉移到細胞核內，與核內的轉錄因子tcf lef結合，啟動與細胞增殖有關的基因轉錄。 -
Since evidence shows anti - estrogen drugs will fail in a many patients with estrogen - receptor - positive breast cancer, says knudsen, our research suggests that physicians should examine both estrogen receptor status and rb tumor suppressor status during the initial diagnosis, in order to prescribe the most effective therapy for that specific patient ' s cancer.
證據表明，抗雌激素藥物對雌激素受體陽性乳癌將失效，我們的研究提示，為了給那些特殊癌癥患者制定最有效的治療方法，醫生應該在開始診斷時檢測雌激素受體和rb抑癌基因狀況。 -
Since eidence shows anti - estrogen drugs will fail in a many patients with estrogen - receptor - positie breast cancer, says knudsen, our research suggests that physicians should examine both estrogen receptor status and rb tumor suppressor status during the initial diagnosis, in order to prescribe the most effectie therapy for that specific patient ' s cancer.
證據表明，抗雌激素* *物對雌激素受體陽性乳癌將失效，我們的研究提示，為了給那些特殊癌癥患者制定最有效的治療方法，醫生應該在開始診斷時檢測雌激素受體和rb抑癌基因狀況。 -
In recent years, studies indicated these molecular markers mainly involved : oncogenes and tumor - suppressor genes mutate or rearrange in some thyroid neoplasms ; the exceptional increasing on the activity of telomerase ; the special proteins which are related to cell cycle regulation or adhesion express excessively ; as well as some special matter which is discovered recently
近年研究表明這些分子標志物主要涉及癌基因或抑癌基因的突變或重排；端粒酶活性的異常增高；一些與細胞周期調控或與粘附有關的特殊蛋白的表達；以及一些新發現的特異物質。 -
Tumor suppressor gene
腫瘤抑制基因 -
Neoplasia, or uncontrolled cellular proliferation, can result either from mutations that " turn on " the oncogenes that stimulate growth, or from mutations that result in loss of tumor suppressor genes and their products that inhibit growth
腫瘤或失去控制的細胞增生是由於突變使癌基因啟動從而促使增生，或者由於腫瘤抑制基因和腫瘤抑制基因產物的缺失。 -
For example, as a direct toxic effect, periodontal iruses and bacteria and their products ( endotoxins or enzymes, for example ) are toxic to surrounding cells and may directly induce mutations in tumor suppressor genes and proto - oncogenes or alter signaling pathways that affect cell proliferation or surial of epithelial cells
例如，作為直接毒性作用，牙周病毒和細菌及在細胞周圍其產生的毒性物質（例如，類毒素或酶類）可直接誘導腫瘤抑制基因和原癌基因突變或者改變細胞信號傳導通路從而影響上皮細胞增殖或存活。 -
For example, as a direct toxic effect, periodontal viruses and bacteria and their products ( endotoxins or enzymes, for example ) are toxic to surrounding cells and may directly induce mutations in tumor suppressor genes and proto - oncogenes or alter signaling pathways that affect cell proliferation or survival of epithelial cells
例如，作為直接毒性作用，牙周病毒和細菌及在細胞周圍其產生的毒性物質（例如，類毒素或酶類）可直接誘導腫瘤抑制基因和原癌基因突變或者改變細胞信號傳導通路從而影響上皮細胞增殖或存活。 -
Endogenous angiogenesis inhibitors act as tumor suppressor proteins
內源性血管生成抑制劑可作為一種抑癌蛋白。 -
Moreover, some oncogenes and tumor suppressor genes are also important in cell cycle regulation ; those include myc, ras, p53, p21 and p16
另外，癌基因和抑癌基因也在細胞周期調控中起到關鍵作用，癌基因如： myc ， ras等；抑癌基因如： p53 ， p21 ， p16等等。 -
8p22 of human chromosome is an region rich in disease - related genes and is also the susceptible loci of oncogenes and tumor suppressor genes
人染色體8p22區是一個富含疾病基因的區域，是癌基因和抑癌基因的研究熱點。 -
This silencing also affects the function of many tumor suppressor genes, which, in their unmethylated state, put the brakes on uncontrolled cell growth
這種沉默也影響許多抑癌基因的功能，這些基因在非甲基化狀態下可以阻止不受控制的細胞生長。 -
Tumor - suppressor genes normally protect cells from becoming cancerous, but the gradual silencing of these genes by abnormal methylation is thought to be an early change in cancer deelopment
抑癌基因通常是阻止細胞腫瘤化，隨著這些基因不正常的甲基化，他們就開始沉默，這被視為腫瘤的早期改變。 -
Doc - 1r gene is an candidate tumor suppressor gene which was discovered by zhangxue. it can interact with cdk2 specifically and restrain cdk2 transportation into the nucleus, which will block the formation of cdk2 and cyclin complex and hinder the process of cell cycle
Doc - 1r基因是張學等發現的一個候選抑癌基因，它可與cdk2特異性結合，抑制cdk2的入核轉運，使cdk2不能與cyclin形成復合物，從而阻抑細胞周期的進程。 -
The spatial and temporal gene expression patterns, and the gene loss - of - function and gain - of - function can be easily tested in the zebrafish embryo system. recently, we identify a zebrafish novel tumor suppressor gene
利用斑馬魚胚胎系統可以很容易的了解基因表現的位置和時間，以及利用基因功能減損或增加的技術，可以簡易的推測人類新穎基因的功能。 -
Basal cell neus syndrome is caused by a tumor suppressor gene, called ptch, located on chromosome 9. mutations in this gene may increase the risk of oarian cancer
謝謝樓主給大家發這么典型的片子，基底細胞痣綜合癥的臨床資料比較缺乏，這對大家講學和經驗積累很有幫助.多謝，新年快樂
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