tumor-specific 中文意思是什麼

tumor-specific 解釋
腫瘤特異性的
  • tumor : n. 【醫學】腫瘤，癌，疙瘩，贅疣。 a benign [malignant] tumor 良[惡]性腫瘤。adj. -ous 腫瘤的；誇張的 （tumorous growth 【農業】陡長）。
  • specific : adj 1 特殊的；特有的；特定的，專門的。2 明確的，具體的。3 【生物學】種的；【細菌】專性的。4 【醫...
  1. From the new point of view, looking for tumor - specific proteins with proteomics research strategy may help to elucidate the correlation of the change of protein expression to oncogenesis, and may play a vital role in the early detection of cancer and anticancer therapy including drug exploitation

    腫瘤蛋白質組學從新的角度研究腫瘤，尋找腫瘤標志蛋白，進而闡明其表達水平的變化與腫瘤發生、發展的相互關系，對腫瘤的早期診斷、治療、藥物研發等方面具有重要意義。
  2. Based on this consideration, we chose human colorectal cancer cell line ccl229 as the experimental object, down - regulating its grp94 expression by specific ribozyme targeting. we observed its effects on the biological characteristics of ccl229 and upr pathway, and gained further understand of the grp94, upr and tumor relationship

    基於此，我們選擇了人大腸癌細胞株ccl229作為研究對象，通過特異性核酶打靶的方式，下調細胞中grp94的表達水平，觀察其對人大腸癌細胞某些生物學特性及upr通路的影響，加深對grp94 、 upr和腫瘤這三者間關系的了解。
  3. Numbers of specific regulatory t cells ( tr ) in breast tumor biopsies offer a aluable indicator of disease prognosis and progression, researchers claim

    研究者宣稱，在乳腺腫瘤活組織檢測中大量的特異調控的t細胞對于該疾病的預后及進展提供了有價值的參考。
  4. The specific bronchoscopic picture highlights the value of bronchoscopy in the differential diagnosis of endobronchial tumor

    藉由這位病人其腫瘤在支氣管鏡下的特殊表現，彰顯了支氣管鏡對于支氣管內腫瘤的鑒別診斷之重要性。
  5. Since evidence shows anti - estrogen drugs will fail in a many patients with estrogen - receptor - positive breast cancer, says knudsen, our research suggests that physicians should examine both estrogen receptor status and rb tumor suppressor status during the initial diagnosis, in order to prescribe the most effective therapy for that specific patient ' s cancer.

    證據表明，抗雌激素藥物對雌激素受體陽性乳癌將失效，我們的研究提示，為了給那些特殊癌癥患者制定最有效的治療方法，醫生應該在開始診斷時檢測雌激素受體和rb抑癌基因狀況。
  6. Since eidence shows anti - estrogen drugs will fail in a many patients with estrogen - receptor - positie breast cancer, says knudsen, our research suggests that physicians should examine both estrogen receptor status and rb tumor suppressor status during the initial diagnosis, in order to prescribe the most effectie therapy for that specific patient ' s cancer.

    證據表明，抗雌激素* *物對雌激素受體陽性乳癌將失效，我們的研究提示，為了給那些特殊癌癥患者制定最有效的治療方法，醫生應該在開始診斷時檢測雌激素受體和rb抑癌基因狀況。
  7. Preparation of specific anti - tumor immune rna

    特異性抗腫瘤免疫核糖核酸的提取
  8. Heat shock proteins ( hsps ) are molecular chaperones with potent adjuvant capability in the induction of antigen - specific ctl, thl response and increasing immunogenicity of tumor cells

    本課題應用a20腫瘤細胞，經熱休克作用，制備熱休克腫瘤細胞來源的exosomes 。
  9. At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells

    但是，學者們發現這一療法存在著如下的缺陷：單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用，且有誘導免疫耐受的潛在危險，有時反而會促進腫瘤的生長；事先需對患者的hla單倍型進行鑒定，以確定ctl表位與hla單倍型是否匹配，目前尚缺乏能與所有hla單倍型相匹配的ctl表位，從而限制了這一療法的應用；這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞，但對腫瘤細胞的殺傷能力較弱：這種l表位抗原肽缺乏cd4汀h細胞相關的表位，因此，不能誘導有效的th細胞免疫應答。
  10. Dendritic cells ( dc ), the initiator and modulator of immune response, are the most powerful professional antigen - presenting cells ( apc ). recent studies indicated that dc have the most power to activate tumor specific ctl, therefore, dc are applied in the therapy of tumors, e

    機體的抗腫瘤免疫主要為t淋巴細胞所介導， t細胞的致敏、激活、擴增和對腫瘤細胞的殺傷作用均有賴于抗原遞呈細胞腫瘤遞呈相應的抗原肽及相關因子的參與。
  11. The specific niches within it may provide a sanctuary for subpopulations tumor cells that affords a survival advantage following initial drug exposure and may promote acquired drug resistance

    腫瘤微環境中特殊的生態位可能為腫瘤細胞亞群提供了一個「避難所」 ，即在最初暴露于化療藥物之後提供了一種生存優勢，它促進了腫瘤獲得性耐藥的發生。
  12. Tumor antigens of hepatocellular carcinoma and its specific cellular immunity

    肝癌的腫瘤抗原與特異性細胞免疫
  13. It has been reported by candido et al ( 2001 ) that intratumoral delivery of dc could efficiently induce specific antitumor immunity, resulting in tumor growth inhibition in established breast cancer

    若能通過直接瘤內注射的方法，讓dc在腫瘤局部獲得相應的腫瘤抗原以誘導機體產生抗腫瘤免疫，無疑是最經濟、最簡便、具有臨床應用前景的方法。
  14. It delivers the false ? folding peptides for presentation to proteasomes in normal cells, while in tumor cells it acts as main tumor - resistant antigen, inducing specific immune response. recent research found that grp94 also relates with cell cycles, differentiation and apoptosis

    此外發現它還具有抗原提呈作用，在正常細胞中參與折疊錯誤蛋白到蛋白酶體的提呈；在腫瘤細胞中作為主要的腫瘤排斥抗原，引發針對該腫瘤細胞的特異性免疫反應。
  15. Conclusion : apoptotic - tumor - cell - loaded dc induced maturation by cd40mab could efficiently induce the activation and proliferation of tumor specific ctl, and the combination of il - 2, il - 15, cd28mab was a very powerful method to expand antigen specific ctl in vitro

    結論： cd40mab激發的凋亡腫瘤細胞負載dc在cd28mab 、 ilj和il上的聯合作用下可有效激活和擴增腫瘤特異性cth 。
  16. Ascribed to the discoveries of many tumor specific / associated antigens ( tsas / taas ) and the unique / excellent properties of antibody, the antibody - mediated targeting therapy of tumor persistently attracts worldwide attentions

    由於許多腫瘤特異性抗原或相關抗原被發現以及抗體具有獨特而優越的性能，抗體介導的腫瘤靶向治療一直受到廣泛關注。
  17. Filamentous bacteriophage displayed tumor - specific antigen epitope mage - a1 induced cellular immune in mice

    展示腫瘤特異性抗原表位的噬菌體在小鼠體內引起的細胞免疫變化
  18. Kurane s, kranss jc, watari e, et al. targeted gene transfer for adenocarcinoma using a combination of tumor - specific antibody and tissue - specific promoter [ j ]. jpn j cancer res, 1998, 89 ( 11 ) : 1212

    李芳，伍新堯，郭語彬，等.陽離子脂質體介導肺癌細胞基因轉移效率的比較研究[ j ] .中山醫科大學學報， 2000 ， 21 （ 6 ） : 484
  19. Biomicroarray is mainly composed of gene microarray, protein microarray and tissue microarray, which may function in identifying tumor - specific markers for gastric cancer

    基因晶元、蛋白晶元與組織晶元構成了生物晶元的主體，該技術有望在胃癌特異性標志物發現上發揮作用。
  20. The trial ' s preliminary results indicate the vaccine was associated with tumor - specific immune response in patients with recurrent, high - grade glioma

    研究結果初步顯示疫苗可使復發的惡性膠質瘤患者產生腫瘤特異性免疫反應。
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