嵌合抗體基因 的英文怎麼說
中文拼音 [qiàngěkàngtǐjīyīn]
嵌合抗體基因
英文
chimeric antibody gene-
The characteristics of tm - 22 expression presented in transgenic tobacco : 1 ). virus specificity in either homozygote or heterozygote ; 2 ) tm - 22 gene integrated in tobacco genomic dna with single copy and in inheritance and segregation to progenies on the mendel role ; 3 ). transgenic line with tm - 22 promoter ( ptm47 ) showed infected symptoms with cell death distinguished to one with 35s promoter ( ptm49 ) after inoculation with tomv - 2a
其次,通過氨基酸序列和結構的比較,確定tm - 2 ~ 2基因的編碼蛋白與tomv病毒在抗病反應中相互識別的特異氨基酸及其功能;然後,應用重組dna技術,互換tm - 2 ~ 2基因和tm - 2基因的對應結構域,構建嵌合基因,獲得嵌合蛋白表達的轉化體,驗證tm - 2 ~ 2編碼蛋白中變異氨基酸的作用。Objectives to improve the effect of a single mtb8. 4 dna vaccine, we constructed a chimeric mtb8. 4 / hil - 12 eukaryotic plasmid by linkage of mycobacterium tuberculosis mtb8. 4 gene to human il12 gene with a simple linker ( gly4 - ser ) 3. we analyzed the immunogenicity of chimeric dna vaccine and investigated the immune responses elicited when mtb8. 4 / hil12 was presented as endogenous ag
目的:以il - 12作為分子佐劑,與結核桿菌新抗原mtb8 . 4基因連接形成嵌合分子,將其克隆到真核表達質粒中,構建成嵌合dna疫苗,研究其在小鼠體內誘導細胞免疫應答的效果及對c57bl 6n小鼠的免疫保護作用,為尋求安全、有效、廉價的結核病新疫苗打下基礎。Because expressed in escherichia coli, ricin a chain is not degraded easily for its non - glycosylation. our experiments lay a foundation for the researches that rta conjugates a monoclonal antibody to synthesize immunotoxins and the immunotoxins are used for cancer - targeted therapy
蓖麻毒素a鏈在大腸桿菌中表達,因無糖基化修飾,克服了進入體內后被迅速降解的缺點,為進一步與單鏈抗體基因嵌合表達形成單鏈免疫毒素,對腫瘤細胞進行導向治療研究奠定基礎。2. an anther specific chimaeric male sterile gene expression box with a enhanced promoter ( ta29 ) driving coda gene was constructed and the expression box was inserted into binary vector p3301 that contains a l - phosphinothricin ( ppt ) - resistant selective marker gene and - glucuronidase ( gus ) reporter gene in t - dna region
以增強的ta29啟動子驅動克隆的coda基因,構建成花藥特異性嵌合基因表達盒;將此表達盒插入雙元載體p3301 ,構建成以ppt抗性基因為選擇標記,以gus為報告基因的植物表達載體。分享友人