核內蛋白 的英文怎麼說

中文拼音 [hénèidànbái]
核內蛋白 英文
nuclear protein
  • 核 : 核構詞成分。
  • 內 : 名詞1. （內部; 里頭; 里邊） inner; inside; within 2. （妻子或妻子的親屬） one's wife or her relatives 3. （姓氏） a surname
  • 蛋 : 名詞1. （鳥類或龜、蛇類所產的卵） egg 2. （像蛋形的東西） an egg-shaped thing 3. （辱罵之詞）
  • 白 : Ⅰ形容詞1 （似雪的顏色） white 2 （清楚; 明白; 弄明白） clear 3 （空的; 沒加他物的） pure; clear; ...
  • 蛋白 : 1. （卵中透明的膠狀物質） egg white; albumen; gary2. [生物化學] （蛋白質） protein
  1. To investigate the consequence of this interaction, aes - rfp fusion protein expression vector was constructed and co - transfected into nih 3t3 cells with tle1 - gfp fusion protein expression vector. confocal microscopy observation showed that aes could interact with tle1 at the cytomembrane region. moreover, this interaction inhibited the concentration of tle1 into nucleus

    在構建了紅色熒光蛋白aes表達載體后，將其與tle綠色熒尤蛋白載體共轉染細胞，共聚焦顯微鏡觀察發現這兩種分子在胞漿中有共存現象，而且aes的表達可抑制tlei向胞核內的聚積。
  2. Translocation from endocytic compartments to the cytosol is the essential and rate - limiting step in the intoxication process of most toxins such as ricin, diphtheria toxin, shiga toxin and pseudomonas exotoxin ( pe ). a number of these toxins are transported to trans - golgi network ( tgn ), and in many cases such transport to the tgn is required for the translocation and cytotoxicity. in deed, 5 % of the ricin endocytosed by cells has been shown to reach the tgn

    蓖麻毒素進入細胞的機理不甚明了，一般認為是rtb先與細胞膜受體結合，主要經過受體介導的內吞作用進入吞噬體，然後沿著內體、高爾基體、內質網等逆向分泌途徑，有序地運輸到內質網，最後從內質網轉位進入細胞漿，在胞漿內攻擊核糖體，從而抑制蛋白質的合成，導致細胞死亡。
  3. It has been shown that this occurs in bacteria in that antisense rna sets up base pairs with a certain messenger rna ( m - rna ) precisely where the ribosomes would start their reading

    這些蛋白質通過核糖體聚合在一起，且他們是通過沿著的閱讀和翻譯信使rna氨基酸的序列而行成，這就決定了各種蛋白質在細胞內的不同功能。
  4. Uppsala university scientists have discovered an entirely new process in which short, tiny " antisense rna " competes with the protein - producing ribosomes for starting sites for reading messenger rna

    烏普薩那大學的科學家們發現了一個全新的進程，在短期內，微小的「反義核糖核酸」具有與製造蛋白質的核糖體競爭信使rna起始位點的能力。
  5. G gene of rabies virus m, the of two main regions ( about 1000nt ), ranging from 3161nt to 4162nt and ranging from 4012nt to 4863nt of glycoprotein gene of rabies virus strain m, isolated from mouse in he nan, china were amplified by reverse transcriptase - polynerase chain reaction ( rt - pcr ) in order to complete glycoprotein gene of strain m. these regions were sequenced by the produce of pcr directly. comparison and analysis of nucleotide sequence and amino acid sequence deduced with that of other strains published was performed by computer with dnasisv 2. 5demo software

    本研究對我國河南某地野鼠體內分離的狂犬病野毒株mrv基因的3161位? 4162位（ 1001個堿基）和4012位? 4863位（ 851個堿基）片段進行了反轉錄pcr擴增和序列測定，得到mrv的糖蛋白基因全序列，用dnasisv2 . 5demo分析軟體，與已發表的代表性毒株g基因全序列進行核苷酸和氨基酸序列的比較分析，結果表明在同一基因型中， mrv和國際標準攻毒株cvs的同源性最高（ 96 . 5 ） ，和中國減毒株ctn的同源性最低（ 79 . 8 ） 。
  6. Any of the proteinaceous cylindrical hollow structures that are distributed throughout the cytoplasm of eukaryotic cells, providing structural support and assisting in cellular locomotion and transport

    蛋白質圓柱形空心結構，廣泛存在於真核細胞的細胞質中，為細胞內的移位和傳輸提供結構支持和協助。
  7. The ribosomes, made up of rna and protein, are found either lining the endoplasmic reticulum or free within the cell.

    核糖體由蛋白質和RNA組成，有的排列在內質網上，有的則在細胞中呈游離狀態。
  8. This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected

    本研究以蛋白質分子設計的理論和方法研究避孕疫苗，將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合，獲得新抗原- 35肽序列；並在合成、純化後分別與弗氏佐劑、免疫刺激復合物（ iscoms ）混合后免疫不同遺傳背景的雌性小鼠，觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變：以及在ivf下，新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。
  9. Oxygen - evolving psil core complexes treated with hydrophilic crosslinker edc showed a little change in the microenvironments of tyr and trp residues. however, oxygen - evolving psil core complexes treated with hydrophobic crosslinkers such as dcc, hmdi, egs, and dtsp showed a distinctly change in both the microenv

    Egs 、 dtsp對psll放氧核心復合物蛋白質中tyr 、 trp微環境和682urn處葉綠素熒光影響大，可能它們參與了psll放氧核心復合物內部的蛋白疏水區域交聯。
  10. Methods : hyperosmotic pressure animal model was established by administering 3 % sodium chloride as drinking water to rats or increasing osmotic pressure of the culture medium. osmoregulation positions in the brain, reciprocal projection pathways between the medullary visceral zone ( mvz ) and supraoptic nucleus ( son ) or hypothalamic paraventricular nucleus ( pvn ), oscillation of intracellular calcium in cultured neurons and astrocytes were studied by means of anti - fos, glial fibrillary acidic protein ( gfap ), tyrosine hydroxylase ( th ) or vasopressin ( vp ) multiple imrnunohistochemical staining, immuno - electronic microscope, wga - hrp retrogradely tracing and cell culture methods. results : ( 1 ) fos positive neurons within the mvz, parabrachial nuclei, locus ceruleus, pvn, son, subfomical organ increased markedly

    方法：通過給予大鼠飲用3氯化鈉或提高培養基滲透壓濃度的方法復制高滲刺激模型，主要採用抗fos 、膠質原纖維酸性蛋白（ gfap ）和酪氨酸羥化酶（ th ） （或加壓素? vp ）免疫組織化學多重染色、免疫電鏡、 wga - hrp束路追蹤結合免疫組織化學多重染色、細胞培養等實驗方法，系統觀察了中樞參與滲透壓反射的調控部位、下丘腦視上核（ son ）神經元? ast超微結構的變化、延髓內臟帶（ mvz ）和son及下丘腦室旁核（ pvn ）之間往返投射通路和神經元的性質及其與ast的關系、培養神經元和ast內鈣波的變化。
  11. It still remains a question whether the rearrangements of igh come from h / rs cell or the background lymphocytes. in this study, we have detected the igh clonal correlation between the h / rs cells and the background cells, from a new aspect to study the clonality of h / rs cell and its relation with the background cells. the expression of b - cell - specific activator protein ( bsap ) was detected in hl. igh gene rearrangements were analysed by the methods including gene analysis in neoplasms tissue and micropicked cells from paraffin - embedded sections, sequencing to test the pcr product, and in situ pcr

    本研究將在以往研究的基礎上，在國內率先把b細胞核反式作用因子? b細胞特異性激活蛋白（ b - cell - specificactivatorprotein ， bsap ）應用於hl的研究，檢測hl的bsap表達，並採用石蠟刮片組織和微切割單細胞的基因分析、測序分析和間接原位pcr等方法，同步觀察分析h rs和背景淋巴細胞的igh基因克隆相關性，從又一個新視角探究chl的腫瘤性h rs細胞克隆性及與背景淋巴細胞的關系。
  12. Many glycoproteins of lower and higher eucaryotes are attached to the plasma membrane by means of a glycosylphosphatidylinositol ( gpi ). gpi - anchored proteins are synthesized on membrane - bound ribosomes. upon translocation of the pro - protein across the endoplasmic reticulum membrane, gpi : protein transamidase ( gp1t ) recognize and removes the carboxy terminal gpi signal sequence and attaches a gpi molecule to the newly exposed carboxy terminal amino acid

    Gpi化前體蛋白在依附於膜的核糖體上合成，當其易位穿過內質網（ er ）膜后，被gpi ：蛋白質轉酰胺基酶（ gpit ）識別， gpit在移走其羧基端gpi信號序列的同時將gpi分子連接至新生成的氨基酸位點上。
  13. Human bone morphogenetic protein 3 is a member of tgf - b superfamily. lt can induce the differentiation of cartilage and bone tissue in mesenchymal cell. and is important to bone self - repairment and bone development during embryo morphogenesis. in addition, some other biological activities of hbmp - 3 have also been found. such as inducing development of embryo and stimulating differentiation of neural and blood cells. therefore, there is a great prospect in the use of hbmp - 3. there is trace content of hbmp - 3 in human body. it has been expressed in the expression system of eukaryotes and prokaryotes respectively, but its application is restricted because of defects in the process and modification after translation in prokaryotic cells and higher costs and lower yields existed in eukaryotic expression system

    人骨形成蛋白3 （ hbmp - 3 ）屬于tgf -超家族的一員，可以誘導間充質細胞分化為軟骨和骨，在胚胎時期骨骼發育和骨再生修復中起著重要的作用，而且對胚胎發育過程中中胚層的誘導和分化、造血組織的發育以及神經系統的發育和修復等都起著重要作用，因而hbmp - 3有廣闊的市場前景。它在人體內含量極微，盡管研究人員已經在原核細胞和真核細胞表達系統中分別進行了表達，但是由於原核表達系統缺乏翻譯后的加工修飾，真核表達系統存在成本高、產量低等特點，限制了其在臨床上的應用。
  14. Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues, and in this situation, the ccc has been disrupted and cell adhesion function disturbed. a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc, and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription

    當-連環蛋白酪氨酸或絲氨酸殘基磷酸化后，就與ajs發生解離而游離到細胞漿中，此時細胞的粘附功能也發生障礙，游離到胞漿中的-連環蛋白，一部分被抑癌因子apc降解，一部分則轉移到細胞核內，與核內的轉錄因子tcf lef結合，啟動與細胞增殖有關的基因轉錄。
  15. The new synthesized protein was led to endoplastic reticulum cavity by eukaryotic secretory signal peptide sequence and then anchored to innerwall of endoplastic reticulum by kdel sequence, which interdicted the process of protein entering golgi body and cytoplasm, and then avoided heterogeneous glycosylation modification of foreign protein and prolonged the disappearance of half life of protein in organism. 2

    真核分泌信號肽序列可以引導新合成的蛋白質進入內質網腔， kdel序列將進入內質網腔的蛋白質錨定在內質網內壁上，從而阻斷了蛋白質進入高爾基體和細胞質的過程，進而避免了外源蛋白質的異源糖基化修飾，延長了蛋白質在生物體內的半衰期。
  16. It is toxic for most mammalian cells since ricin a chain ( rta ) is an rna specific n - glycosidase that removes a specific adenine residue in a highly conservative region from among over 4000 nucloside residues present in 28s rrna, and causes protein synthesis inhibition and cell death

    Rta具有n -糖苷酶活性，可催化28srrna在4234位脫去腺嘌呤，使核糖體60s亞基失活，從而抑制蛋白質合成，導致細胞死亡。 b鏈（ rtb ）是結合鏈，能和細胞表面半乳糖受體結合，協助a鏈進入細胞內。
  17. With the base of related research on nucleic acid immunization, the technology was used to develop th e research and application of cpti transgenic plant. a new antibody preparation method by nucleic acid immunization to assay the expression of the transgenic gene was explored and compared with the traditional one which immune animal by protein

    在國內外大量核酸免疫的研究基礎上，本研究首次將核酸免疫技術應用於轉基因植物檢測研究中，探討一種核酸免疫法制備抗cpti抗體來檢測基因表達的方法，並與傳統的蛋白免疫方式制備抗體進行比較。
  18. Protein and nucleic acid in yeast cells were degraded, then the product was refined into nutritional seasoning, which was in step with current tide of nutrition and nature

    摘要酵母抽提物亦稱酵母味素，是將酵母細胞內蛋白質、核酸等進行生物降解，經加工而成的營養型天然調味料，符合目前「天然、營養、回歸自然」之潮流。
  19. High metabolic rates thus lead to increased injury to cells and the nucleic acids, proteins and fats within them

    因此高代謝速率會增加細胞以及其內的核酸、蛋白質與脂肪所受到的傷害。
  20. The axudl gene consists of five exons and encodes a nuclear protein with 63kd molecular weight. it was frequently down - regulated in lung, kidney, liver and colon cancers compared with their corresponding normal tissues

    該基因含有五個外顯子，其編碼產物為分子量63kd的細胞核內蛋白，該基因在肺癌、腎癌、肝癌和結腸癌中的表達較相應的正常組織均明顯降低。
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