核酸類藥物 的英文怎麼說
中文拼音 [hésuānlèiyàowù]
核酸類藥物
英文
nucleic acid drugs- 核 : 核構詞成分。
- 酸 : 酸構詞成分。
- 類 : Ⅰ名1 （許多相似或相同的事物的綜合; 種類） class; category; kind; type 2 （姓氏） a surname Ⅱ動詞...
- 藥 : Ⅰ名詞1 （藥物） medicine; drug; remedy 2 （某些有化學作用的物質） certain chemicals Ⅱ動詞1 [書面...
- 物 : 名詞1 （東西） thing; matter; object 2 （指自己以外的人或與己相對的環境） other people; the outsi...
- 核酸 : [生物化學] nuclein; nucleic acid核酸聚合酶 nucleic acid polymerase; 核酸酶 nuclease; 核酸內切酶 [生物化學] endonuclease
- 藥物 : medicinal; medicine; medicant; medication; drug; pharmaceuticals; medicaments
-
Research interests : organic synthesis, including synthetic methodology, divergent oriented organic synthesis, asymmetric synthesis, asymmetric synthesis of small molecules with biological significance ( alkaloids, amino acids, pheromones, nucleosides analogues, enzyme inhibitors, receptor agonists and antagonists, bioactive heterocycles etc ) and chiral drugs
研究興趣：主要從事有機合成化學及相關的化學生物學研究，包括合成方法學、多樣性導向有機合成、不對稱合成、有機小分子調節劑（生物堿，氨基酸，昆蟲信息素，酶抑制劑，受體拮抗劑，核苷類似物等）和手性藥物的不對稱合成。Pharmacogenomics combines traditional pharmaceutical sciences such as biochemistry with annotated knowledge of genes, proteins, and single nucleotide polymorphisms
藥物基因組學結合了傳統藥學理論（如生物化學）和已經定義了的基因、蛋白質和單核苷酸多態性等各類學科的研究成果。The cdna expression library that contains no intron theoretically include all expressed genes and conserve resource genes permanently. lt can be used to find out and clone some genes which can express particular protein with modern molecular biological techniques, such as immunological screening, drug - prob screening, southern et al. lt is very important to study the life nature of plasmodium falciparum in molecular level. with the developments of these studies, the drug - resistant mechanism of the plasmodium falciparum and the genes of some specific medicine binding protein can be made well - known. at the same time, the researches will do good to explain the mechanism of some specific medicines in order to design and screen new anti - malaria drugs
建立cdna表達文庫在一次永久保存基因資源的同時，可以利用功能篩選、免疫學篩選、藥物探針篩選、 southern雜交和大規模序列測定等現代分子生物學技術尋找特異性活性蛋白基因，進而克隆和表達這些基因，對從核酸及蛋白質等分子水平研究瘧原蟲的生命活動規律，對揭示其抗藥性分子機理，搞清某些特效藥物結合蛋白的基因及此類藥物的作用機制，對新型抗瘧藥物的合理設計及篩選都具有極其重要的現實意義。
分享友人