結瘤蛋白 的英文怎麼說
中文拼音 [jiēliúdànbái]
結瘤蛋白
英文
nodulation protein-
In addition, axud1 has a high homologue with transforming growth facotr beta ( tgf - ) induced apoptosis protein 2 and 12 using blast exploration at genebank database. these suggest that axudl may have a tumor - suppressor function in these organs and may play an important role in tgf - - induced apoptosis
通過genkbank上blast的搜索結果表明， axud1與tgf -誘導的凋亡蛋白2 、 12 （ taip - 2 、 taip - 12有較高的同源性，提示axud1可能是一個具有腫瘤抑制功能的基因，並可能在tgf -誘導的細胞凋亡中起著重要作用。In addition, it was also found that this protein shares limited but significant homology with the sam - dependent methyltransferase of mesorhizobium sp. bnc1 ( 32 % similarity ), and the similarity of its 303 - 362 region to the 160 - 220 domains of l11 methyltransferases of e. coli ( prma ) is 41 %. it is suggested that methylation of l11 resulted in effects of noea on nodulation of 042bm
發現noea與中慢生根瘤菌（ mesorhizobiumsp . ） bnc1可能的sam -依賴性的甲基轉移酶相似性為32 ，而其303 - 362區域與大腸桿菌（ escherichiacoli ）的核糖體50s亞基的l11蛋白甲基轉移酶（ prma ）的160 - 220結構域的相似性達到41 。Almost one - third of all proteases can be classified as serine proteases, including complement subcomponent clr / cls, mannose - associated serine proteases ( masps ), ovochymase, spermadhesin, type ii transmembrane serine proteases ( ttsps ) etc. these proteins are involved in diverse biological processes, including developmental processes such as complement activation, ovulation, fertilization, tissue remodeling, cellular migration, cancer invasion and metastasis, intestinal digestion, embryogenesis, or organogenesis
絲氨酸蛋白酶（ serineprotease ）是機體最重要的酶分子之一，約占機體蛋白酶的三分之一，我們較熟知的絲氨酸蛋白酶就包括補體組分c1r c1s 、甘露糖結合絲氨酸蛋白酶、 ovochymase 、 spermadhesin和型跨膜絲氨酸蛋白酶等，它們參與了補體活化、排卵、授精、組織重建、細胞遷移、腫瘤浸潤和轉移、消化、胚胎發育、器官形成等多項生理功能。Mdr1 express product p - glycoprotein was detected by immunocytochemical method and flowcytometry. the cytotoxicity and multidrug resistance reversion effect of tea polyphenol was examined by mtt assay in mcf - 7 and mcf - 7 adr carcinoma cell lines, and compared with pgp inhibitor quinidine. the pgp expression of mcf - 7 adr was strongly positive, the positive rate was 15 % ; the pgp expression of mcf - 7 was negative, the positive rate was 1. 8 %. ic50 of tea polyphenol to mcf - 7 and mcf - 7 adr is 115. 2g ml and 207. 6g ml respectively. ic50 of quinidine to mcf - 7 and mcf - 7 adr is 129. 8mol l 42. 1g ml and 94. 1mol l 30. 5g ml respectively. tea polyphenol and quinidine changed little toxicity of adriamycin to mcf - 7, but tea polyphenol and quinidine improved the sensitivity of mcf - 7adr to adriamycin significantly. immunocytochemistry and flow cytometry can detect p - glycoprotein expression level qualitatively and quantitatively. tea polyphenol is not only an anti - tumor agent, but also a multidrug resistant modulator similar as quinidine. tea polyphenol is advantageous for its little toxicity in tumor treatment
用免疫組化法和流式細胞儀對腫瘤細胞系mcf - 7和mcf - 7 adr的p -糖蛋白表達水平進行定性定量研究。用噻唑藍比色法mtt研究茶多酚的細胞毒性及其對耐藥性的逆轉作用，並與pgp抑制劑奎尼定進行了比較。免疫組化法檢測p -糖蛋白表達水平， mcf - 7 adr呈強陽性，而mcf - 7呈陰性流式細胞儀定量檢測結果mcf - 7 adr細胞系細胞陽性率為15 % ， mcf - 7細胞系細胞陽性率為1 . 8 % 。H - caldesmon in diagnosis of smooth muscle tumors of the uterus
鈣調蛋白結合蛋白在子宮平滑肌腫瘤診斷中的意義To investigate the mechanism of trefoil factor 3 on the gastric intestine epithelial restitution, the recombinant human trefoil factor 3 was added to human colonic tumor cell and the proliferation effect was examined by mtt assay. the recombinant protein didn t promote the proliferation of the hct cells at low density of 0. 010. 05 g l and only has weakly proliferation effect at density of 0. 10. 2 g l. 1 g l of the recombinant protein could significantly promote the cell migration of hct cells when added to the monolayers cells
將重組人三葉因子3 trefoil factor 3 ， tff3作用於人結腸腫瘤細胞，研究重組蛋白對細胞增殖的影響，結果發現該蛋白在較低的濃度1050 mg l下對細胞的增殖基本沒有影響，在100200 mg l濃度下該蛋白對細胞僅有微弱的刺激作用，提高濃度對細胞增殖作用沒有改變。同時研究了tff3對損傷的單層結腸腫瘤細胞遷移的影響，發現tff3對細胞有明顯的促進遷移作用。Conclusion : folate - bsanp could be delivered into tumor cells via folate receptor - mediated endocytosis and significantly targeted to tumor cells with rich folate receptors
結論葉酸偶聯白蛋白納米粒能通過細胞膜上的葉酸受體介導內吞入胞，可顯著靶向于葉酸受體豐富的腫瘤細胞。The symbiosis between mesorhizobium huakuii and astragalus sinicus is a chinese - characteristic symbiotic nitrogen fixation system, while molecular genetic study on its early symbiotic interaction is still at primary stage
本文對新型報告基因?綠色熒光蛋白基因在華癸中生根瘤菌-紫雲英共生固氮體系早期結瘤階段分子遺傳學中的應用進行了探索性研究。Researches showed that purified lta27 had the same antitumor activity with lt but far more low toxicity in vivo
初步動物實驗結果表明，純化的lt 27在體內的抗腫瘤作用與淋巴毒素完整蛋白相當，但毒副作用卻小得多。The sds - page electropheresis of whole - cell proteins was applied in classification of 71 strains isolated from astragalus spp. it was showed that the technique is a simple and rapid method in classification of rhizobia. the similarity of strains in the same group is 78 %, and dna homology is above 70 %
採用sds page技術對71株黃芪根瘤菌進行了全細胞蛋白的聚類分析.結果表明，這是進行根瘤菌分類時一種簡便快速的分群方法，分群的菌株相似性水平為78 ，群內菌株的dna同源性70The recombinant fasl - ecd was purified and its biological activity was analyzed on several cell lines and the most sensitive cell lines are selected. ( 2 ) using a computer program, a single short peptide is derived from antisense homology box of fas ligand and is chemically synthesized. ( 3 ) examine the apoptosis - inducing effect of the recombinant fasl - ecd and the ten - peptide on the most sensitive cell lines, and the relationship between them was analysed
純化重組蛋白fasl - ecd ，並分析其生物學活性，篩選出對之最敏感的腫瘤細胞株； （ 2 ）根據生物信息學軟體分析結果，選取fasl胞外區256 - 265的十肽（ n ） - hlyvnvsels - （ c ）作為目標分子，委託生物公司合成該十肽； （ 3 ）分析fasl - ecd和十肽對最敏感腫瘤細胞的毒性作用，分析重組fasl一ecd及十膚作用的相關性。In order to further investigate the role of axudl in human tumor carcinogenesis and the potential association between the axudl gene expression status and the stimulation of transforming growth factor beta in human cancers, the present study was performed in three aspects as follows : ( 1 ) cloning full length enconding region cdna of axudl and construction of eukaryotic vector that expression the fusion protein of axud1 and influenza virus hemagglutin ha epitope tag ; ( 2 ) exploring the time and dose effects of tgf - 1 on the expression - of axudl gene in hepg2 hepatoma cells and spc - a1 lung carcinomas cells, and studying the effects of overexpression of axud1 on the expression of cell cycle and apoptosis related protein in hepg2 hepatoma cells ; ( 3 ) construction and expression of human axudl in e. coli m15. the following main results and conclusions can be obtained from the present study : 1. the full length ecnoding region of human axudl cdna from human peripheral blood lymphocytes was successfully cloned using one step rt - pcr method, and constructed into a eukaryotic expression vector which can be expressed a ha - axud1 fusion protein with axud1 and influenza virus hemagglutin ha epitope tag. the recombinant plasmid was identified by polymerase chain reaction, restriction endonuclease maping and sequencing, this expression vector might be instrumental to further study the function of axud1 protein in tumor cells
為了進一步研究axud1在人類腫瘤發生中的作用及axud1基因的表達狀況與tgf -介導的信號通路的關系，本實驗研究分為三個部分： （ 1 ） axud1基因cdna全長編碼區的克隆和ha表位標記的axud1基因表達載體的構建； （ 2 ）探討肝癌細胞hepg2和肺腺癌spc - a1細胞中tgf - 1誘導的axud1基因表達的時間、劑量效應以及誘導表達的可能機理，並研究axud1的過表達對細胞周期和細胞凋亡相關蛋白表達的影響； （ 3 ） axud1原核表達載體的構建及其在大腸桿菌中的表達。本實驗的主要結果和結論如下： 1利用一步法rt - pcr成功地從人類外周血淋巴細胞中克隆出axud1基因編碼區cdna ，並將其構建入真核表達載體中，編碼的ha - axud1融合蛋白帶有流感病毒凝血素ha的表位標記肽段。8kb cdna with 1362bp orf and codes 454 amino acids with only a sh2 domain. the gene was named as sh2a at chromosome 8p22. we study its structure by blast homologous analysis and its expression by rt - pcr and northern blot
本文將通過蛋白質分析軟體研究其結構和同源性，利用rt - pcr和northern印跡雜交技術研究該基因的表達情況及該基因與腫瘤的關系。Proteome techniques have widely been applied to the fields of plant genetics, plant development, and plant physiology and ecology to investigate plant genetic diversity, plant development such as seed maturation and germination processes, differentiation of plant tissue and organ, separation and functional identification of novel component of various organells, mechanisms of plant adapted to abiotic or biotic stresses including high temperature, low temperature, high salt, drought, and pathogens and insects, and interaction of plant with microbe
摘要蛋白質組技術已廣泛應用於植物遺傳、發育和生理生態等諸多生物學領域，主要研究植物的遺傳多樣性、植物發育（如種子成熟與發芽過程） 、組織器官的分化過程、不同亞細胞結構的新蛋白組分的發現及其功能鑒定、植物對非生物逆境（包括高溫、低溫、高鹽和乾旱等）和生物逆境（病蟲害）的適應機制和植物與微生物（根瘤共生體）相互作用機制。Advances in antibody engineering make it possible to produce various recombinant proteins that exploit the specificity of the antibody - combining site to manipulate tumour - related signalling, and to stimulate anti - tumour immune responses
抗體工程的進展使得製造不同的重組蛋白成為可能，而這些重組蛋白可以利用抗體結合位點的特異性來操縱腫瘤相關信號及刺激抗腫瘤免疫反應。7 when the murine model were immunized by the 5 kinds of elicited hcv - specific ctls as a role of t - cell vaccine, significant inhibition to hcv transplanting tumor were observed in groups of pl p3
以此細胞系建立了皮下移植瘤hcv小鼠模型，經免疫組化葉大， spz 0 hcv細胞及其移植瘤組織內均有hcv結構蛋白的表達。Pp24 protein is suspected to bind with pp38 protein, another kind of specific protein and both of these two protems play an important part in ocongenesis
該蛋白在天然狀況下可能與mdv的另一個特異性蛋白- pp38以異二聚體的形式結合在一起，共同在mdv的致腫瘤中發揮作用。分享友人